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Perinatal Asphyxia

Randomized Controlled Trial between Levetiracetam and Phenobarbital in the Treatment of Neonatal Seizure due to Perinatal Asphyxia

Randomized Controlled Trial between Levetiracetam and Phenobarbital in the Treatment of Neonatal Seizure due to Perinatal Asphyxia

... for hypoxia induced neonatal seizure. No such sutdy was done comparing safety and efficacy of levetiracetam with phenobarbitone in seizure due to perinatal asphyxia. So this study is intended to evaluate ...

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A Study of Nucleated RBC in Cord Blood as a Prognostic
Marker of Perinatal Asphyxia

A Study of Nucleated RBC in Cord Blood as a Prognostic Marker of Perinatal Asphyxia

... of asphyxia by comparing levels of NRBC/100 white blood cells (WBC) and absolute NRBC counts in cord blood between 50 asphyxiated (case group) and 50 normal neonates (control ...

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Patterns and implications of MR contrast enhancement in perinatal asphyxia: a preliminary report

Patterns and implications of MR contrast enhancement in perinatal asphyxia: a preliminary report

... PURPOSE: To determine the presence and location of MR contrast enhancement in infants with perinatal asphyxia and to evaluate the utility of enhancement in assessing extent of brain damage. METHODS: ...

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Urinary uric acid or urinary creatinine ratio as a non-invasive marker for perinatal asphyxia

Urinary uric acid or urinary creatinine ratio as a non-invasive marker for perinatal asphyxia

... Perinatal asphyxia is the common cause of neonatal morbidity and mortality in developing ...diagnose perinatal asphyxia such as magnetic resonance tomography, cranial tomography, and ...

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Clinico laboratory determinants of outcome among babies with perinatal asphyxia in Osogbo, Southwestern Nigeria

Clinico laboratory determinants of outcome among babies with perinatal asphyxia in Osogbo, Southwestern Nigeria

... of perinatal complications like convulsions, apnoea, feeds intolerance, necrotizing enterocolitis (NEC) among the asphyxiated ...15 Perinatal asphyxia has multisystemic or multiorgan adverse effects ...

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Effect of perinatal asphyxia and carbamazepine treatment on cortical dopamine and DOPAC levels

Effect of perinatal asphyxia and carbamazepine treatment on cortical dopamine and DOPAC levels

... Perinatal asphyxia (PA) is a principal cause of long-term neurological disability [1], and its severity appears to de- pend on the intensity of the initial asphyxial event (within the moderate to severe in ...

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Serum Hsp70 antigen: Early diagnosis marker in perinatal asphyxia

Serum Hsp70 antigen: Early diagnosis marker in perinatal asphyxia

... Perinatal asphyxia was defined based on the presence of at least two of the following clinical findings: 1) Fetal dis- tress signs (heart rate of less than 100 beats/minute, late decelerations, or an ...

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Use of Prophylactic Phenobarbitone for Prevention of Morbidity and Mortality in Term Neonates Following Perinatal Asphyxia

Use of Prophylactic Phenobarbitone for Prevention of Morbidity and Mortality in Term Neonates Following Perinatal Asphyxia

... study, prophylactic phenobarbitone was given as 20 mg/kg intravenously slowly over 20 minutes in the case group before the occurrence of seizures while standard treatment of perinatal asphyxia was given to ...

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Effect of perinatal asphyxia on level of thyroid hormones in term neonates

Effect of perinatal asphyxia on level of thyroid hormones in term neonates

... with perinatal asphyxia requiring bag and mask ventilation for ≥1 minute or APGAR at 1 and 5 minute ≤7 or required intubation for resuscitation as cases and control -60 normal term newborn with APGAR ≥7 at ...

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Gold nanorods/siRNA complex administration for knockdown of PARP-1: a potential treatment for perinatal asphyxia

Gold nanorods/siRNA complex administration for knockdown of PARP-1: a potential treatment for perinatal asphyxia

... Background: Perinatal asphyxia interferes with neonatal development, resulting in long-term deficits associated with systemic and neurological ...in asphyxia-exposed animals worsens the ATP-dependent ...

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Incidence of multiorgan dysfunction in perinatal asphyxia

Incidence of multiorgan dysfunction in perinatal asphyxia

... of perinatal asphyxia which occurs due to diving reflex wherein there is redistribution of blood flow to vital organs like brain, heart and ...continued asphyxia there is hypotension, loss of ...

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Umbilical cord blood nucleated red cell count as a marker of perinatal asphyxia

Umbilical cord blood nucleated red cell count as a marker of perinatal asphyxia

... Overall the present study showed that, the cord blood nRBCs has a potential of being used as a simple marker for determining the severity and predicting the in-hospital pre-discharge outcome of fetal asphyxia. The ...

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Comparative Trial of Phenobarbitone vs Phenytoin in Moderate and Severe Perinatal Asphyxia in Term Neonates

Comparative Trial of Phenobarbitone vs Phenytoin in Moderate and Severe Perinatal Asphyxia in Term Neonates

... A prospective, hospital-based open-label randomised trial was conducted with primary aim to compare the clinical seizure control after administration of either drug, Phenobarbitone or Phenytoin in term neonates with ...

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Early neonatal Glutaric aciduria type I hidden by perinatal asphyxia: a case report

Early neonatal Glutaric aciduria type I hidden by perinatal asphyxia: a case report

... Perinatal asphyxia (PA) occurs in about 2 to 10 per 1000 live full-term births, due to oxygen deprivation during labour of sufficient duration to cause injury, mostly to the ...neonatal asphyxia may ...

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Selective Head Cooling in Newborn Infants After Perinatal Asphyxia: A Safety Study

Selective Head Cooling in Newborn Infants After Perinatal Asphyxia: A Safety Study

... after perinatal asphyxia is a practical method of quickly reducing cerebral temperature, with an increased gradient between the surface of the scalp and core ...

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Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia

Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia

... The highest copeptin cord blood concentrations were found in neonates with perinatal asphyxia. This finding was confirmed by multivariate analysis adjusted for gestational age, birth weight, mode of ...

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Neurodevelopmental Outcome of Infants Treated With Head Cooling and Mild Hypothermia After Perinatal Asphyxia

Neurodevelopmental Outcome of Infants Treated With Head Cooling and Mild Hypothermia After Perinatal Asphyxia

... with perinatal asphyxia and the presence of all of the following entry criteria: 1) gestational age ⬎ 37 weeks; 2) 5-minute Apgar score ⱕ6 or cord/first arterial pH ...

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Whole Body Cooling (WBC) for newborn infants with perinatal asphyxia: A feasibility trial

Whole Body Cooling (WBC) for newborn infants with perinatal asphyxia: A feasibility trial

... This is to certify that the dissertation entitled “Whole Body Cooling (WBC) For Newborn Infants With Perinatal Asphyxia: A Feasibility Trial” is a bonafide, original work done by Dr. Koshy C. George, during ...

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Beneficial effect of intravenous magnesium sulphate in term neonates with perinatal asphyxia

Beneficial effect of intravenous magnesium sulphate in term neonates with perinatal asphyxia

... Perinatal asphyxia is a major cause of early neonatal ...fetus. Perinatal asphyxia is determined by a complex interaction of various maternal, placental, uterine and fetal factors from ...

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Magnesium Sulfate in Severe Perinatal Asphyxia: A Randomized, Placebo-Controlled Trial

Magnesium Sulfate in Severe Perinatal Asphyxia: A Randomized, Placebo-Controlled Trial

... severe perinatal asphyxia, as manifested by 3 of the following 4 criteria: (1) history of fetal distress (late deceleration, loss of beat-to-beat variability, fetal bradycardia, or meconi- um-stained ...

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