Periodontal ligament stem cell
Original Article MiR-218 promotes osteogenic differentiation of periodontal ligament stem cell through activation of Wnt signaling by targeting SFRP2
... adipose-derived stem cells and embryonic stem ...in periodontal ligament stem cell (PDLSCs) differentiation remains poorly ...
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Nrf2 Inhibits Periodontal Ligament Stem Cell Apoptosis under Excessive Oxidative Stress
... It is well known that the nuclear factor-erythroid 2-related factor 2 (Nrf2) signaling pathway has an antioxidant effect and is involved in the cellular antioxidant defense system [14, 15]. Under normal conditions, ...
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Bone repair by periodontal ligament stem cell-seeded nanohydroxyapatite-chitosan scaffold
... the osteogenic differentiation of stem cells. Biomimetic mineralization approaches of assembling a nanostructured apatite layer throughout a three-dimensional porous bone tissue engineering scaffold, ie, ...
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Effect of cryopreservation on proliferation and differentiation of periodontal ligament stem cell sheets
... the cell sheets were disrupted and the resultant cells were detached by being treated with a final concentration of ...resulting cell suspension was incu- bated for 30 min at 37 ...
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Influence of nanotopography on periodontal ligament stem cell functions and cell sheet based periodontal regeneration
... (99.9%) (Northwest Institute for Nonferrous Metal Research, Xi’an, People’s Republic of China) were used for cellular and animal studies, respectively. After polishing with SiC sandpaper, from 400 to 1,500 grit, and ...
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Cell transfer technology for tissue engineering
... novel cell transplantation method “ cell transfer technology ” utilizing ...for cell-based therapy using several disease ...endothelial cell-transferred amnion enhanced the reperfusion in ...
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Original Article Insulin-like growth factor-1 promotes proliferation, migration and osteoblasts differentiation of periodontal ligament stem cells via activating PI3K/AKT signal pathway
... Figure 3. Insulin like growth factor-1 (IGF-1) promoted osteogenic differentiation of periodontal ligament stem cell (PDLSC). PDLSCs cultured in the medium supplement with 100 ng/ml IGF-1, ...
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Stem cells : All to optimize periodontal health outcomes
... of Periodontal Ligament Stem Cells In the past, cloning of periodontal ligament fibroblast has met with little ...proliferating periodontal ligament stem cells are ...
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From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells
... mesenchymal stem cells (MSCs) and epithelial stem cells play essential roles in tissue repair and ...epithelial stem cells can be isolated from adult human oral tissues, for example, teeth, ...
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Low-intensity pulsed ultrasound upregulates osteogenesis under inflammatory conditions in periodontal ligament stem cells through unfolded protein response
... years, cell tissue engineering (CTE) technol- ogy has become a promising tissue repair strategy [5], in which stem cells are one of the three basic elements ...In periodontal tissue engineering, ...
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Enhancement of periodontal tissue regeneration by transplantation of osteoprotegerin-engineered periodontal ligament stem cells
... important cell resources for periodontal tis- sue engineering; among them, PDLSCs are a candidate cell source for periodontal regeneration and have proven to be the ideal seeding cells for ...
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Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial
... for cell colony-forming ability and osteogenic/adipogenic differentiation ...for cell isolation and characterization are pre- sented in Additional file 2 (Appendix ...PDL cell sheets obtained from ...
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LncRNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) regulates the proliferation of human periodontal ligament stem cells and toll-like receptor 4 (TLR4) expression to improve periodontitis
... PTCSC3 is a tumor suppressor in both thyroid carcin- oma and glioma [20, 21], and overexpression of PTCSC3 inhibits tumor progression by inhibiting cancer cell pro- liferation. Consistently, our study also showed ...
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The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells
... in cell-cell contact culture or Transwell cultures, whereas the immunosuppressive effect of PDLSCs from adult individ- uals was weaker than that of PDLSCs from young ...
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Original Article MicroRNA-18b mediates the inhibitory effects of nicotine on periodontal ligament-derived stem cell
... relative cell viability value was lower in nicoti- ne-treated cells, compared with untreated con- trol (Figure 3A, ...higher cell viability than all- star transfected cells at all detection point ...3B). ...
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Comparison of Periodontal Ligament Stem Cells Isolated from the Periodontium of Healthy Teeth and Periodontitis-Affected Teeth
... of cell proliferation in healthy and periodontitis-affected groups was ...The cell population doubling time was calculated using the formula below [26]: ...
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Adenovirus-mediated transfer of hepatocyte growth factor gene to human dental pulp stem cells under good manufacturing practice improves their potential for periodontal regeneration in swine
... including periodontal intrabony defects, without damaging soft tissues or creating an ...and periodontal ligament, but at the same time it can preserve soft tissue attachments, which may be ...
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Lapine periodontal ligament stem cells for musculoskeletal research in preclinical animal trials
... Periodontitis, a bacterial-induced inflammatory disorder of the periodontium characterised by the destruction of PDL, cementum and alveolar bone, is one of the major reasons for tooth loss worldwide [1]. The aim of ...
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The role of the Wnt/β-catenin signaling pathway in the proliferation of gold nanoparticle-treated human periodontal ligament stem cells
... with cell proliferation. Many related signaling pathways of stem cell proliferation have an intrusive cross-talk with Wnt ...promoting cell prolifera- tion [11, ...
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Evaluating the oxysterol combination of 22(S)-hydroxycholesterol and 20(S)-hydroxycholesterol in periodontal regeneration using periodontal ligament stem cells and alveolar bone healing models
... their target gene ABCA1 in PDLSCs during osteogenic differentiation. Conversely, the knockdown of both LXRα and LXRβ significantly inhibited the oxysterol- induced osteogenic differentiation of PDLSCs. Previous studies ...
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