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Peripheral Nerve Injury

Heat shock protein 27: Developmental regulation and expression after peripheral nerve injury

Heat shock protein 27: Developmental regulation and expression after peripheral nerve injury

... Peripheral nerve injury alters gene expression in primary sensory ...its peripheral target, such as the downregulation of neurofilament expression (Wong and Oblinger, ...neurons, ...

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Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury

Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury

... [47]. Nerve injury induced upregulation of MeCP2 and a decrease in miR-126 in mice after ...that nerve injury induces the enriched binding of MeCP2 to miR-126 locus, resulting in miR-126 ...in ...

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Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury

Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury

... how peripheral nerve injury (PNI) may have caused World War ...after injury. Nevertheless, peripheral nervous system (PNS) axon regrowth is hampered by nerve gaps created by ...

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Temporal and Qualitative Differences in the Development of Allodynic Behaviors between Mice and Rats in a Peripheral Nerve Injury Model

Temporal and Qualitative Differences in the Development of Allodynic Behaviors between Mice and Rats in a Peripheral Nerve Injury Model

... spared nerve injury (SNI) model of neuropathic pain was first developed by Decosterd and Woolf in 2000 in Sprague Dawley rats to enhance reproducibility of injury and behavioral res- ponses resulting ...

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Peripheral nerve injury-induced alterations in VTA neuron firing properties

Peripheral nerve injury-induced alterations in VTA neuron firing properties

... We performed recordings in slices from the lateral and med- ial VTA to ascertain putative plasticity in DA neurons as a result of peripheral nerve injury (leading to neuropathic pain). Prior to ...

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Enhanced neuroinflammation and pain hypersensitivity after peripheral nerve injury in rats expressing mutated superoxide dismutase 1

Enhanced neuroinflammation and pain hypersensitivity after peripheral nerve injury in rats expressing mutated superoxide dismutase 1

... Even though increased processing of experimental noci- ceptive stimuli was recently evidenced in ALS patient [66], the study of pain in the context of ALS was out of the scope of the present research which essentially ...

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Peripheral nerve injury with Nexplanon removal: case report and review of the literature

Peripheral nerve injury with Nexplanon removal: case report and review of the literature

... contraception. Peripheral nerve injury from any cause often carries a poor prognosis and causes significant disability for pa- ...after nerve reconstruction is unfortunately not uncommon: the ...

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Systemic functional enrichment and ceRNA network identification following peripheral nerve injury

Systemic functional enrichment and ceRNA network identification following peripheral nerve injury

... Peripheral nerve injury is a worldwide clinical issue that impacts patients ’ quality of life and causes huge society and economic ...Injured peripheral nerves are able to regenerate by ...

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Roles of nitric oxide and ethyl pyruvate after peripheral nerve injury

Roles of nitric oxide and ethyl pyruvate after peripheral nerve injury

... the injury site forms peroxynitrite with NO, which is a powerful antioxidant that helps in the initiation of lipid peroxidation ...this, peripheral nerve injury is also cor- related with ...

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Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes

... of peripheral nerve ...after injury while Nlrp6 showed a sharper expression peak ...upon injury, while NOD1 and IPAF did not increase in expression level ...the nerve, we sorted Schwann ...

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Original Article Deceased expression of prostatic acid phosphatase in primary sensory neurons after peripheral nerve injury

Original Article Deceased expression of prostatic acid phosphatase in primary sensory neurons after peripheral nerve injury

... of peripheral nerve injury on the expression of PAP has not been reported until ...after peripheral nerve injury and reaches the bottom at the ...

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Tor1a+/- mice develop dystonia-like movements via a striatal dopaminergic dysregulation triggered by peripheral nerve injury

Tor1a+/- mice develop dystonia-like movements via a striatal dopaminergic dysregulation triggered by peripheral nerve injury

... In principle, the role of striatal dopaminergic neurotrans- mission as an important modifier for the manifestation of dystonia in a multistep pathophysiological pathway is widely accepted already because inherited ...

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Application of topical pharmacological agents at the site of peripheral nerve injury and methods used for evaluating the success of the regenerative process

Application of topical pharmacological agents at the site of peripheral nerve injury and methods used for evaluating the success of the regenerative process

... the nerve tissue, suggesting its neuroprotective, free radicals scavenging, antioxidative, and analgesic effects in degenerative dis- eases of peripheral ...to peripheral nerves ...ing ...

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Temporal changes in macrophage phenotype after peripheral nerve injury

Temporal changes in macrophage phenotype after peripheral nerve injury

... tissue injury and repair [64, 65, 68, 69], are essential for the initiation of angiogenesis and attrac- tion and proliferation of precursor cells required for repair ...in peripheral nerve ...

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Whole limb kinematics are preferentially conserved over individual joint kinematics after peripheral nerve injury

Whole limb kinematics are preferentially conserved over individual joint kinematics after peripheral nerve injury

... A peripheral nerve injury was generated in each animal through a previously described surgical procedure (Cope et ...tibial nerve with a longitudinal incision in the popliteal fossa of the ...

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A Clinical Study on the Treatment of Peripheral Nerve Injury Growth Factor of Mecobalamin Combined with Nerve

A Clinical Study on the Treatment of Peripheral Nerve Injury Growth Factor of Mecobalamin Combined with Nerve

... treatment peripheral nerve injury growth factor of Mecobalamin combined with ...with peripheral nerve injury treated in the hospital in July were selected from 2011 to ...injured ...

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Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice

Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice

... Although peripheral nerves can regenerate after injury, proximal nerve injury in humans results in minimal restoration of motor ...that injury-induced axonal growth is too ...after ...

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Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat

Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat

... and nerve injury, in which microglia and astrocytes produced proinflammatory cytokines by activat- ing TLRs ...alleviate peripheral nerve injury-induced neuropathic ...

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Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury

Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury

... Next, we examined whether peripheral administration of TC-2559 and another nAChR ligand, sazetidine A, affect neuropathic pain following PSL. On the ipsilateral side, mechanical allodynia defined by the reduction ...

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SPLINTING THE HAND WITH A PERIPHERAL-NERVE INJURY

SPLINTING THE HAND WITH A PERIPHERAL-NERVE INJURY

... Unlike patients with median or ulnar nerve palsy, in whom sensory and intrinsic muscle loss impedes hand function, the patient with radial palsy has the potential for[r] ...

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