perivascular adipose tissue
Obesity related perivascular adipose tissue damage is reversed by sustained weight loss in the rat
... 5. Greenstein AS, Khavandi K, Withers SB, Sonoyama K, Clancy O, Jeziorska M, Laing I, Yates AP, Pemberton PW, Malik RA, Heagerty AM. Local inflammation and hypoxia abolish the protective anticontractile properties of ...
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The influence of perivascular adipose tissue on vascular homeostasis
... Abstract: The perivascular adipose tissue (PVAT) is now recognized as an active contributor to vascular function. Adipocytes and stromal cells contained within PVAT are a source of an ever-growing ...
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Effect of Peroxynitrite (ONOO ) on the Function of Murine Perivascular Adipose Tissue
... DOI: 10.4236/pp.2019.104017 204 Pharmacology & Pharmacy [9] da Costa, R.M., Fais, R.S., Dechandt, C.R.P., Louzada-Junior, P., Alberici, L.C., Lo- bato, N.S. and Tostes, R.C. (2017) Increased Mitochondrial ROS ...
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Early alterations in vascular contractility associated to changes in fatty acid composition and oxidative stress markers in perivascular adipose tissue
... We have recently shown that rats fed a FRD present marked changes in plasma lipid and hormone profile, oxidative damage to lipoprotein fractions and their fatty acids (FAs), fat content in the liver, and fatty acyl com- ...
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Endoplasmic reticulum stress in perivascular adipose tissue promotes destabilization of atherosclerotic plaque by regulating GM CSF paracrine
... in perivascular adipose tissue (PVAT) which not only serves a structural support for most arteries but also secretes series of mol- ecules to actively modulate vascular function ...coronary ...
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Sex differences in the regulation of porcine coronary artery tone by perivascular adipose tissue: a role of adiponectin?
... perivascular adipose tissue PVAT - mediated regulation of the porcine coronary artery.. Experimental Approach- Isometric tension recording system was used to record changes in.[r] ...
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Sex differences in the role of phospholipase A2 dependent arachidonic acid pathway in the perivascular adipose tissue function in pigs
... These sex differences in the role of these prostanoids in the PVAT-induced contraction can be explained by a greater release of thromboxane from PVAT from female animals and greater sens[r] ...
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Luseogliflozin attenuates neointimal hyperplasia after wire injury in high-fat diet-fed mice via inhibition of perivascular adipose tissue remodeling
... Sodium-glucose cotransporter-2 (SGLT2) is an api- cal membrane-bound transporter, which is selectively expressed at S1 segment of renal proximal tubular epi- thelial cells, being involved in urinary glucose reabsorp- ...
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Characterisation and comparison of adipose tissue macrophages from human subcutaneous, visceral and perivascular adipose tissue
... Others have also studied CD16 marker positivity in human subcutaneous adipose tissues. Kovacikova [18] found a slightly higher proportion of CD16 positive mac- rophages (approximately 60 %) compared to our data ...
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Coronary artery hypoxic vasorelaxation is augmented by perivascular adipose tissue through a mechanism involving hydrogen sulfide and cystathionine β synthase
... the tissue was assessed using 60 mM ...the tissue had returned to baseline tension, the thromboxane A 2 analogue U46619 (11α,9α-epoxymethano-PGH 2 ) was ...
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Eosinophils are key regulators of perivascular adipose tissue and vascular functionality
... Adipose tissue digest. For isolation of the adipose stromal vascular fraction (SVF), white mesenteric adi- pose tissue was finely minced and incubated in medium containing 1 mg/mL type I ...
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Regulation of vascular tone by adipocytes
... in perivascular adipose tissue ...of perivascular adipose tissue in rat aorta and mouse mesenteric arteries ...cular adipose tissue of stenotic aortas (but not in ...
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... On the other hand, the physiology and morphology of PVAT are influenced by inflammatory cytokines, the sym- pathetic nervous system, and vasoactive peptides [20,22-24]. Despite a growing evidence of the vital role of ...
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Original Article Expression of visfatin influences the development of coronary artery disease
... The experimental tissues were removed the endogenous catalase after dewaxing. After washing with PBS, they were added dropwise 5% BSA and anti-secondary antibody into a 37°C incubator. After drying PBS surrounding ...
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CONCEPT OF DYSLIPIDEMIA IN AYURVEDA & ITS MANAGEMENT – A CONCEPTUAL STUDY .......
... and tissue that store lipid ...and adipose tissue store the greatest amount of body lipids, including triglycerides and free ...and adipose tissue are active from an endocrine and ...
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An inhibitor of 11-β hydroxysteroid dehydrogenase type 1 (PF915275) alleviates nonylphenol-induced hyperadrenalism and adiposity in rat and human cells
... Fatty acid synthase (FASN) is a key enzyme in lipogenesis. Sprague-Dawley rat pups fed with a high-carbohydrate diet exhibited obesity later in life and overexpressed FASN in the liver and adipose tissue ...
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Regulation of adipocyte autophagy — The potential anti-obesity mechanism of high density lipoprotein and ApolipoproteinA-I
... Autophagy, defined as a highly regulated process involv- ing the bulk degradation of cytoplasmic macromolecules and organelles in mammalian cells via the lysosomal sys- tem, plays a housekeeping role in removing ...
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The role of adipose triglyceride lipase in lipid and glucose homeostasis: lessons from transgenic mice
... in adipose tissue TG content ...Interestingly, adipose-specific deletion of ATGL resulted in reduced hepatic leucocyte infiltration and activation, specifically showing resistance to high-fat diet ...
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Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques
... by adipose tissue CD4 T cells compared to peripheral blood CD4 T cells in ART-treated HIV patients ...in adipose tissue, as well as in other extravascular tissues, are predominantly memory CD4 ...
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Deciphering the cellular interplays underlying obesity induced adipose tissue fibrosis
... the adipose mass is mediated by adipo- cyte hypertrophy (enlarged adipocytes) or hyperplasia (increased cell ...of adipose tissue ...of tissue homeostasis and can promote or at least maintain ...
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