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Personalized Medicine (Genomics)

From big data analysis to personalized medicine for all: challenges and opportunities

From big data analysis to personalized medicine for all: challenges and opportunities

... Major investments need to be made in bioinformatics, biomathematics, and biostatistics by the scientific commu- nity to accelerate the transition to personalized medicine. Classic research laboratories do ...

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Genomics in Personalized Medicine

Genomics in Personalized Medicine

... Generally speaking, the knowledge gained from the individual’s genetic make- up is very crucial in determining patients who will benefit from certain drugs or individuals who will not benefit or individuals who will be ...

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Personalized medicine in psychiatry: problems and promises

Personalized medicine in psychiatry: problems and promises

... A rapidly advancing area likely to have a major influence on personalized medicine in psychiatry is neuroimaging, and more specifically, neuroimaging genomics. Briefly, imaging genetics uses imaging ...

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Personalized Medicine, Genomics and Enhancement: Monuments to Neoliberalism

Personalized Medicine, Genomics and Enhancement: Monuments to Neoliberalism

... genomic medicine, ...genomic medicine as a component of ...“Personalized medicine is a broad and rapidly advancing field of health care that is informed by each person’s unique clinical, ...

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Mitochondrial and nuclear genomics and the emergence of personalized medicine

Mitochondrial and nuclear genomics and the emergence of personalized medicine

... where personalized medicine or health care and treatments tailored to individual genomic profiles would become the ...modern medicine has become a long process and has necessitated additional ...

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The significance of microbiome in personalized medicine

The significance of microbiome in personalized medicine

... Modern personalized therapeutic is integrated with each individual genetic structure and disease history before the disease begins, and this is unlike the traditional per- sonalized ...in personalized ...

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Drug repositioning for personalized medicine

Drug repositioning for personalized medicine

... a personalized level has become an attainable ...data. Personalized medicine and repositioning both aim to improve the productivity of current drug discovery pipelines, which expend enormous time and ...

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Implementing personalized medicine with asymmetric information on prevalence rates

Implementing personalized medicine with asymmetric information on prevalence rates

... The application of personalized medicine requires to have instruments (tests) to stratify patients as well as personalized treatments [6]. The selection of the optimal therapy depends on the patient ...

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Personalized medicine in rheumatology: the paradigm of serum autoantibodies

Personalized medicine in rheumatology: the paradigm of serum autoantibodies

... of personalized medicine and discuss the predictive, prognostic and preventive role of antinu- clear antibodies (ANA), anti-citrullinated peptide antibod- ies (ACPA), rare autoantibodies and anti-drug ...

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Personalized Medicine: Emerging as a Silver
Lining in Dentistry

Personalized Medicine: Emerging as a Silver Lining in Dentistry

... Personalized medicine is a revolution in the medical or dental field as it allows prevention and treatment of diseases based on genomic technologies. Information about a patient’s proteinaceous, genetic, ...

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Genetic basis for personalized medicine in asthma

Genetic basis for personalized medicine in asthma

... towards personalized medicine in asthma, with associated benefits including avoidance of adverse side effects and the adequate control of the patients’ asthma, avoiding exacerbation and hospitalization due ...

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A Parallel Software Pipeline for Personalized Medicine

A Parallel Software Pipeline for Personalized Medicine

... Abstract: Personalized medicine is an aspect of the P4 medicine (predictive, preventive, personalized and participatory) based precisely on the customization of all medical characters of each ...

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Personalized medicine and stroke prevention: where are we?

Personalized medicine and stroke prevention: where are we?

... Personalized medicine is a growing field in which a range of diagnostic tests, such as genetic screening and other risk stratification tools, will enable clinicians to develop evidence-based and ...

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Pharmacogenomics in cardiovascular disorders: Steps in approaching personalized medicine in cardiovascular medicine

Pharmacogenomics in cardiovascular disorders: Steps in approaching personalized medicine in cardiovascular medicine

... Abstract: Some of the most commonly prescribed medications are those for cardiovascular maladies. The beneficial effects of these medications have been well documented. However, there can be substantial variation in ...

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The pharmacogenomics of pain management: prospects for personalized medicine

The pharmacogenomics of pain management: prospects for personalized medicine

... of Medicine database PubMed, using search terms “pharmacogenomics”, “genetic poly- morphisms”, or “single nucleotide variants”, and combin- ing with “pain management”, “analgesia”, “single gene pain disorder”, ...

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The role of epigenetics in personalized medicine: challenges and opportunities

The role of epigenetics in personalized medicine: challenges and opportunities

... Hence, crizotinib (Xalkori ® ), an anti-cancer drug that inhibits ROS1 (c-ros oncogene 1) and ALK, is used for the 5% of patients that will respond to this drug because they have a chromosomal rearrangement that produces ...

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Personalized medicine in Europe: not yet personal enough?

Personalized medicine in Europe: not yet personal enough?

... into personalized medicine, each time you look at a smaller subgroup of an extra factor in terms of the evidence of benefit then you get more uncertainty” ...increasing medicine complexity could lead ...

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Implementation and utilization of genetic testing in personalized medicine

Implementation and utilization of genetic testing in personalized medicine

... Although personalized medicine has only recently been acknowledged in medical practice, physicians and researchers have observed interindividual differences in clinical traits and therapy responses for ...

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Perspectives on achieving institutional trust in personalized medicine

Perspectives on achieving institutional trust in personalized medicine

... We use this response to bring to the fore wider scholarship and activities that have already explored issues of institutional trust in detail. We set the scene by highlighting previous scholarship that has problematized ...

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Personalized medicine and treatment approaches in hypertension: current perspectives

Personalized medicine and treatment approaches in hypertension: current perspectives

... highly personalized to the pathophysiol- ogy of individual ...understand personalized medicine must focus on specific, testable ...for personalized hypertension care, influential ...

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