PHA-767491 inhibits Rb phosphorylation and cyclin A expression
Cyclin D1 and Rb protein expression and their correlation with prognosis in patients with colon cancer
... with cyclin D1 or pRb ...with cyclin D1 posi- tive tumors was significantly ...that cyclin D1 expression may be a predic- tor of patients presenting in advanced stage and of patients at young ...
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DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells
... upregulated cyclin D; In contrast, DACH1 acted as an antagonist of cyclin D1 in breast ...mRNA expression from 20 pairs of normal and cancerous tissues showed that higher DACH1 expression is ...
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Alterations of Cyclin dependent kinase 5 expression and phosphorylation in Amyloid precursor protein (APP)-transfected PC12 cells
... of Cyclin dependent kinase 5 (Cdk5) expression and phosphorylation in PC12 cells overexpressing Amyloid precursor protein ...decreased phosphorylation of Cdk5 at Tyr15 was observed in APPsw ...
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Dysregulation of Cyclin E Gene Expression in Human Cytomegalovirus-Infected Cells Requires Viral Early Gene Expression and Is Associated with Changes in the Rb-Related Protein p130
... endogenous cyclin E promoter during the course of ...the cyclin E promoter revealed several regions of protection and hypersensitivity that were unique to infected ...virus-induced cyclin E ...
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Cyclin D1 Expression in Laryngeal Cancer.
... and Cyclin D1 co-expression in laryngeal squamous cell carcinoma: possible target for novel therapeutic strategies 165 ...as Cyclin D1, and tumor suppressor genes such as ...their expression ...
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Expression of Cyclin A in Rectal Mucosa and Rectal Carcinoma.
... vegetables, inhibits the growth of several human colon adenocarcinoma cell lines (COLO 320 HSR, LS-174, HT-29 and WiDr) by inducing cell cycle arrest in G(2)/M phase and ...the expression of cyclin ...
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Expression of Cyclin D1 in normal and hyperplastic endometrium
... express Cyclin D1. Studies in the past have observed the over expression of Cyclin D1 in endometrial hyperplasia and ...of cyclin D1 expression in normal and hyperplastic ...
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Immunohistochemical analysis of cyclin A expression in Wilms tumor
... study, cyclin A overexpression was most often in WT with focal and diffuse anaplasia, and recently it has been suggested that focal anaplasia could have similar prognostic significance as the diffuse ( Sebire & ...
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Original Article miR-448 inhibits proliferation and induces apoptosis in prostate cancer cells by modulating cyclin-dependent kinase 19 expression
... target cyclin-dependent kinase 19 (CDK19) in proliferation and apoptosis of PCa cell ...The expression levels of gene and protein were assayed by qRT-PCR and western blotting, ...Results: Expression ...
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Expression profiling of cyclin B1 and D1 in cervical carcinoma
... and cyclin dependent kinases, have been reported in various malignant ...detect cyclin B1 and D1 in cervical ...the expression of cyclin B1/D1 mRNA and proteins, respectively, in fresh ...
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Cyclin D1 and p16 expression in recurrent nasopharyngeal carcinoma
... of expression of cyclin D1 and p16 in recurrent NPC that have failed pri- mary treatment with radiation +/- ...of expression of cyclin D1 in recurrent NPC was similar to that of previously ...
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Analysis of cyclin A expression in cells with a finite mitotic lifespan
... rat cyclin A gene 141 this gene throughout the cell cycle, inclusion of sequences from intron 1 which included the E2F site, gave cell cycle regulated transcription (Lee et ah, ...human cyclin A promoter to ...
218
Cyclin D1 and D3 expression in melanocytic skin lesions
... Cyclins, cyclin-dependent kinases, as well as proteins cooperating with them are responsible for cell cycle regulation which is crucial for normal development, injury repair, and ...of cyclin-dependent ...
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p34(cdc2) and mitotic cyclin expression in the developing quail neuroretina
... Int I De, BioI ~ I 469 ~76 ( 1997) 469 Original Article p34cdc2 and mitotic cyclin expression in the developing quail neuroretina XAVIER ESPANEl' 3#, ANNE KASTNER", OLIVIER STETTLER', BERTRAND TAVITIA[.] ...
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Expression of Cyclin D1 and P16 in Esophageal Squamous Cell Carcinoma
... for cyclin D1 and negative for ...for cyclin D1 and negative for ...between cyclin Dl over- expression and loss of pl6 expression has not been identified, but these results suggest that ...
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Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression
... This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and ...
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Adenovirus mediated over expression of the cyclin/cyclin dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty
... Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of[r] ...
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Cyclin G2 Inhibits the Warburg Effect and Tumour Progression by Suppressing LDHA Phosphorylation in Glioma
... whether cyclin G2 played a role in glioma progression, and explored whether cyclin G2 regulated glioma cell ...that cyclin G2 was downregulated in glioma compared to normal brain tissue, and the ...
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Regulation of Ciz1 by Cyclin A Cyclin Dependent Kinase 2 (CDK2) mediated phosphorylation
... The CIZ1 gene itself is induced by oestrogen in oestrogen-responsive cell lines. It was discovered that within this gene, there are multiple partial and complete EREs located upstream of exon 1 and the intron between the ...
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Phosphorylation of pRb: mechanism for RB pathway inactivation in MYCN-amplified retinoblastoma.
... elevated cyclin- dependent kinase (CDK) activity prevents pRb from being an effective brake on cell cycle ...high expression of p27 ...UPEN- RB- 201, where it is highly ...
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