Pharmacokinetic parameters
Development and optimization of carvedilol orodispersible tablets: enhancement of pharmacokinetic parameters in rabbits
... Methods: Compatibility among CVD and all tablet excipients using differential scanning calorimetry and Fourier transform infrared spectroscopy, complexation of CVD with different polymers, and determination of the ...
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EVALUATION OF PHARMACOKINETIC PARAMETERS FOR PURE DRUG AND FAST DISSOLVING TABLETS OF MELOXICAM
... of pharmacokinetic data. For the successful conduct of pharmacokinetic study, the development of selective and sensitive bioanalytical methods plays an important role for the quantitative evaluation of ...
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Enhanced renal clearance and impact on vancomycin pharmacokinetic parameters in patients with hemorrhagic stroke
... netic parameters based on population data ...in pharmacokinetic parameters resulted in vancomycin serum trough concentrations lower than predicted ...
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Pharmacokinetic parameters and optimal dosage of a florfenicol and tylosin mixture in beagle dogs
... Antimicrobial combinations are commonly used with the objectives of enhancing efficacy, safety and minimising resistance (Eliopoulos and Moellering 1991). Florfenicol is a derivative of thiamphenicol and chloramphenicol, ...
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Influence of Energy Drinks on Pharmacokinetic Parameters of Sildenafil in Rats
... the pharmacokinetic profile of sildenafil by using HPLC.The pharmacokinetic parameters (Cmax, Tmax and AUC) were determined in 10 rats following oral administration of ...The pharmacokinetic ...
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An annotated corpus with nanomedicine and pharmacokinetic parameters
... Second, the size of the dataset is relatively small. How- ever, we believe that this dataset and the framework developed for its creation can be used to facilitate 1) the development of additional larger-scale datasets ...
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Measurement of pharmacokinetic parameters in histologically graded invasive breast tumours using dynamic contrast enhanced MRI
... their pharmacokinetic parameters allowed a more specific classification of breast cancer lesions than black-box measurements (such as ER, ME and wash-out slope ...of pharmacokinetic ...
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Effect of fluid loading during hypovolaemic shock on caspofungin pharmacokinetic parameters in pig
... loading. Pharmacokinetic analysis showed that the peripheral volume of distribution of caspofungin and intercompartmental clearance were significantly higher in the shock group, as was the total apparent volume of ...
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Glioma: Application of Histogram Analysis of Pharmacokinetic Parameters from T1 Weighted Dynamic Contrast Enhanced MR Imaging to Tumor Grading
... The previous studies presented the parametric values with cut- off values to differentiate low- and high-grade gliomas. The pre- sented values in the previous studies were not consistent with one another. The ...
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Quality Control Of Impurities And Comparison Of Pharmacokinetic Parameters Of Angiotensin Receptor Antagonists
... Metabolites are excreted or participate in the phase II (conjugation): detoxifying reactions: acetylati- on, methylation, conjugation of a drug molecule or its metabolites [r] ...
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Effect of Hyperlipidemia on the Pharmacokinetics of Lercanidipine in Experimental Rats
... the pharmacokinetic parameters of lercanidipine in experimental ...in pharmacokinetic parameters of lercanidipine in hyperlipidemic ...
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Original Article Serum vancomycin levels in critically ill elderly patients undergoing continuous renal replacement therapy
... the pharmacokinetic parameters of vancomycin in critically ill elderly patients un- dergoing Continuous Renal Replacement Therapy (CRRT) and provide a baseline for dose ...CRRT parameters were as ...
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Preparation, characterization, and in vivo evaluation of a self-nanoemulsifying drug delivery system (SNEDDS) loaded with morin-phospholipid complex
... vivo pharmacokinetic parameters of the morin-phospholipid complex self-nanoemulsifying drug delivery system (MPC-SNEDDS) were investigated in Wistar rats (200 mg/kg of morin by oral ...
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Comparative in vivo study of pure drug and fast dissolving tablets of Simvastatin
... the pharmacokinetic patterns between pure drug and an optimized formulation of fast dissolving tablets of ...method. Pharmacokinetic parameters were determined for each ...
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INFLUENCE OF VERAPAMIL ON PHARMACOKINETICS OF PIOGLITAZONE IN NORMAL AND DIABETIC RATS
... The pharmacokinetic parameters of pioglitazone alone, single dose treatment, SDT [verapamil (9 mg/kg ...various pharmacokinetic parameters is AUC ...
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Differential effects of hydrocortisone, prednisone, and dexamethasone on hormonal and pharmacokinetic profiles: a pilot study in children with congenital adrenal hyperplasia
... Results: Nine prepubertal subjects aged 8.1 ± 2.3 years completed the study. Mean ACTH, androstenedione, and 17-hydroxyprogesterone (17-OHP) values were lower following the DEX arm of the study than after subjects ...
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Mefloquine pharmacokinetics and mefloquine artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria
... and pharmacokinetic parameters through Day 56 of three commercial formulations of MQ (Lariam ® , Mephaquin ® , and Mefloquina-AC ® Farma) given in combination ...
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Comparison between the Prebolus T1 Measurement and the Fixed T1 Value in Dynamic Contrast Enhanced MR Imaging for the Differentiation of True Progression from Pseudoprogression in Glioblastoma Treated with Concurrent Radiation Therapy and Temozolomide Chemotherapy
... contrast-enhanced pharmacokinetic parameters, including the volume transfer constant, the rate transfer constant, the blood plasma volume per unit volume, and the extravascular extracellular space per unit ...
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ENHANCED ORAL BIOAVAILABILITY IN ALBINO RABBITS OF LOVASTATIN NANOPARTICLES
... The pharmacokinetic parameters for lovastatin pure drug suspension, marketed formulation and nanoparticles dispersion following oral administration were determined from plasma concentration ...The ...
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PHARMACOKINETIC STUDY OF ANDROGRAPHIS PANICULATA ETHANOLIC EXTRACT TABLET
... Extraction of Andrographis paniculata: Dried aerial part of the Andrographis paniculata was ground to obtain coarse powder using an electric grinder. Powdered drug was extracted with ethanol in 25% concentration (25 gm ...
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