phenolic glycolipid
Phenolic Glycolipid Facilitates Mycobacterial Escape from Microbicidal Tissue Resident Macrophages
... We have exploited the optical transparency of the zebrafish larva to study the early mycobacterium-phagocyte interactions by infecting Mycobacterium marinum (Mm), a close genetic relative of Mtb, into the zebrafish ...
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The Difference in Immunoglobulin M Anti-Phenolic Glycolipid-1 Antibody Levels in Leprosy Patient, Household Contacts, and Control
... Background: Leprosy is a disease caused by M. leprae infection, may affect the peripheral nervous system, skin and other tissues. Until recently, leprosy is still a health problem in Indonesia. Phenolic ...
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Cellular and humoral immune response to a phenolic glycolipid antigen (PhenGL I) in patients with leprosy
... The ability of phenolic glycolipid I PhenGL-I of Mycobacterium leprae to stimulate in vitro lymphocyte proliferation LP was tested in cultures of peripheral blood cells from 42 patients [r] ...
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Analysis of Antibody Responses to Mycobacterium leprae Phenolic Glycolipid I, Lipoarabinomannan, and Recombinant Proteins To Define Disease Subtype-Specific Antigenic Profiles in Leprosy
... leprae-specific phenolic glycolipid I (PGL-I) to disseminated infection with multiple lesions containing huge numbers of AFB, the absence of cell- mediated immunity, and high titers of antibody to PGL-I * ...
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Detection of Phenolic Glycolipid I ofMycobacterium leprae in Sera from Leprosy Patients before and after Start of Multidrug Therapy
... says, phenolic glycolipid I (PGL-I) is still the only Mycobacte- rium leprae-specific antigen (8), and it has been widely used for the serodiagnosis of ...
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Serological responses to prednisolone treatment in leprosy reactions: study of TNF-α, antibodies to phenolic glycolipid-1, lipoarabinomanan, ceramide and S100-B
... to Phenolic glycolipid-1 (PGL-1 IgM and IgG), Lipoarabinomannan (LAM IgG1 and IgG3), C2-Ceramide and S100 B] were analyzed longitudinally in 72 leprosy patients before, during and after the ...
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Production of monoclonal antibody to a phenolic glycolipid of Mycobacterium tuberculosis and its use in detection of the antigen in clinical isolates
... Production of Monoclonal Antibody to a Phenolic Glycolipid of Mycobacterium tuberculosis and Its Use in Detection of the Antigen in Clinical Isolates SANG-NAE CHO,`* JEON-SOO SHIN,1 MAMA[r] ...
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Phenolic-glycolipid-1 and lipoarabinomannan preferentially modulate TCR- and CD28-triggered proximal biochemical events, leading to T-cell unresponsiveness in mycobacterial diseases
... phosphorylation and calcium mobilization. Interestingly, these antigens preferentially curtailed TCR-triggered early downstream signalling events like p38 phosphorylation whereas potenti[r] ...
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Serodiagnosis of leprosy: relationships between antibodies to Mycobacterium leprae phenolic glycolipid I and protein antigens
... leprae antigens as detected by Western immunoblot and the CABA for the 65-kDa antigen was compared with controls and contacts by the x2 test or the Fisher exact probability test.. Also, [r] ...
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Factors associated with anti phenolic glycolipid I seropositivity among the household contacts of leprosy cases
... The consistent significance of the variables related to signs suggestive of disease in the multivariate analysis model provides further evidence for the use of the ML Flow test to identi[r] ...
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Field-Friendly Test for Monitoring Multiple Immune Response Markers during Onset and Treatment of Exacerbated Immunity in Leprosy
... leprae-specific phenolic glycolipid I (PGL-I), al- though not informative for the identification of RR onset (13), represents a useful biomarker for monitoring the efficacy of treat- ment of leprosy ...
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Protocol, rationale and design of PEOPLE (Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar): a cluster randomized trial on effectiveness of different modalities of implementation of post exposure prophylaxis of leprosy contacts
... The study has been designed as a cluster randomized trial in which villages will be randomly allocated to four arms. All villages will be subject to four annual rounds of door-to-door screening. Leprosy patients ...
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Biophysical optima for metabolism of Mycobacterium leprae
... Quantitation of intracellular ATP and the rate of [U-14C]palmitic acid incorporation into phenolic glycolipid I PGL-I were used as metabolic indicators after axenic incubation in modifie[r] ...
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Antigen specific assessment of the immunological status of various groups in a leprosy endemic region
... The aim of this study was to evaluate the antibody responses against phenolic glycolipid-1 PGL-1, natural disaccharide linked to human serum albumin via an octyl NDO-HSA, Leprosy IDRI Di[r] ...
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Chapter 7 Lecture.ppt
... Fibers of extracellular matrix (ECM) Glyco- protein Microfilaments of cytoskeleton Cholesterol Peripheral proteins Integral protein CYTOPLASMIC SIDE OF MEMBRANE Glycolipid EXTRACELLULAR [r] ...
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Mutation of β glucosidase 2 causes glycolipid storage disease and impaired male fertility
... Analysis of glycolipids in Gba2 wild-type and knockout mice. (A) Glycolipids were extracted from tes- tes of 6-, 20-, and 24-month-old mice, resolved by 1-dimensional TLC, and visualized by staining with orcinol. The ...
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PHYSICOCHEMICAL AND PHYTO CHEMICAL ANALYSIS OF MASHA AND MUDGA W S R TO GURU AND LAGHU GUNA
... Molar mass is a unit that enables scientists to calculate the weight of any chemical substance, be it an element or a compound. In derivation of molar mass of sample it was observed that Masha and Mudga are ahar dravya ...
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Alterations of the iNKT cell compartment in brain injured patients
... Specific activation of iNKT cells occurs following the presentation of glycolipid antigens by APCs loaded onto the CD1d molecule. We thus investigated IFN-γ and IL- 13 secretions following activation of iNKT cells ...
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The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction
... Abstract: The objective is to discuss about the correlation of Glycolipid Metabolism, Cystatin C (CysC) and Homocysteine (Hcy) of thyroid dysfunction. 100 cases of hyperthyroidism, hypothyroidism and the control ...
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Enzyme linked immunosorbent assay of glycolipid antigens for identification of mycobacteria
... Enzyme-linked immunosorbent assays which are based on species- or type-specific glycolipid antigens and in which rabbit antisera are prepared with homologous strains are capable of disti[r] ...
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