pig-tailed macaque
Evolution of a Human Immunodeficiency Virus Type 1 Variant with Enhanced Replication in Pig-Tailed Macaque Cells by DNA Shuffling
... the pig-tailed macaque (Macaca nemestrina) has been reported to support HIV-1 replication ...in pig-tailed macaques (2, 15, 16), causing only small and transient declines in CD4 cells ...
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Complete Genome Sequence of Pig-Tailed Macaque Rhadinovirus 2 and Its Evolutionary Relationship with Rhesus Macaque Rhadinovirus and Human Herpesvirus 8/Kaposi's Sarcoma-Associated Herpesvirus
... ⫽ pig-tailed macaque) clusters with RRV (host ⫽ rhesus macaque) within the RV2 lineage of Old World primate rhadinoviruses (8, 16, ...long-tailed macaque, clustered closely with ...
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A Variant Macaque-Tropic Human Immunodeficiency Virus Type 1 Is Resistant to Alpha Interferon-Induced Restriction in Pig-Tailed Macaque CD4+ T Cells
... in macaque T cells (85, 88–91, ...counteract macaque APOBEC3 proteins with a SIV vif substitution and evade rhesus or cynomolgus TRIM5␣-mediated restriction with a CA ...and pig-tailed ...
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Phylogenetic relationships of Malaysia’s pig tailed macaque macaca nemestrina based on d loop region sequences
... The separation of Borneo and Peninsular Malaysia populations of M. nemestrina is highly anticipated, considering the vicariance theory on population disjunction. In this scenario, Borneo and Peninsular Malaysia ...
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Next-Generation Sequence Analysis of the Genome of RFHVMn, the Macaque Homolog of Kaposi's Sarcoma (KS)-Associated Herpesvirus, from a KS-Like Tumor of a Pig-Tailed Macaque
... the pig-tailed macaque homolog of Kaposi’s sarcoma-associated herpesvirus (KSHV), was determined by next-generation sequence analysis of a Kaposi’s sarcoma (KS)-like macaque ...
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Adaptation of Subtype A Human Immunodeficiency Virus Type 1 Envelope to Pig-Tailed Macaque Cells
... The usefulness of SHIV models, particularly as tools to examine the biology of HIV-1 transmission and strategies to prevent infection, depends on how well they mimic HIV-1 transmission and early infection in humans. ...
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Linking Pig-Tailed Macaque Major Histocompatibility Complex Class I Haplotypes and Cytotoxic T Lymphocyte Escape Mutations in Simian Immunodeficiency Virus Infection
... SIV-infected pig-tailed macaque model, and few CTL epitopes have been ...in pig-tailed macaques and their escape mutations are KP9 in Gag (13, 14) and KSA10 and KVA10 in Tat (15), all ...
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Spontaneous meningioma in a pig-tailed macaque (Macaca nemestrina)
... Received: 8 December 2017 – Revised: 21 February 2018 – Accepted: 12 March 2018 – Published: 5 April 2018 Abstract. We present a case of spontaneous meningioma in a female pig-tailed macaque (Macaca ...
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Genetic differences accounting for evolution and pathogenicity of simian immunodeficiency virus from a sooty mangabey monkey after cross-species transmission to a pig-tailed macaque.
... Apart from point mutations in SUgpl20, a unique cluster of five nucleotide changes at positions 7205 to 7211 was observed that led to three amino acid changes: amino acids 378 to 380 are[r] ...
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Vif Substitution Enables Persistent Infection of Pig-Tailed Macaques by Human Immunodeficiency Virus Type 1
... monkeys, pig-tailed macaques (Pt) are uniquely susceptible to human immunodeficiency virus type 1 (HIV-1), although the infection does not ...juvenile pig-tailed macaques, the Pt-tropic HIV-1 ...
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Characterization of Plasmacytoid Dendritic Cells in Bone Marrow of Pig-Tailed Macaques
... ODN or inactivated influenza virus, HLA-DR expression on BM-pDCs increased three- to fivefold above MFI levels de- tected ex vivo. While the mean MFI of HLA-DR on the sur- face of PB-pDCs increased to similar levels in ...
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Isolation and Characterization of a Neuropathogenic Simian Immunodeficiency Virus Derived from a Sooty Mangabey
... in macaque macrophage popula- ...in pig-tailed macaque macrophages than in rhesus macaque ...In pig- tailed macaque macrophages, low levels of virus replication ...
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A Species-Specific Amino Acid Difference in the Macaque CD4 Receptor Restricts Replication by Global Circulating HIV-1 Variants Representing Viruses from Recent Infection
... (hu), pig-tailed (pt), or rhesus (rh) CD4 were infected with GFP-reporter viruses derived from the subtype A Q23-17 envelope with known differences in ptCD4 re- ceptor usage ...in pig-tailed ...
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Genotyping of TRIM5 locus in northern pig tailed macaques (Macaca leonina), a primate species susceptible to Human Immunodeficiency Virus type 1 infection
... Sunda pig- tailed macaque (M. nemestrina), Northern pig-tailed macaque ...studied pig- tailed macaques may contain individuals of different spe- ...
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Development of Whole-Virus Multiplex Luminex-Based Serological Assays for Diagnosis of Infections with Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 Homologs in Macaques
... of pig-tailed macaques against RRV-infected cell cultures by ...51 pig-tailed macaques from an outdoor breeding colony of the WaNPRC for seroreactivity to RV2 lineage rhadinoviruses, using an ...
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Rhesus Macaque Resistance to Mucosal Simian Immunodeficiency Virus Infection Is Associated with a Postentry Block in Viral Replication
... from viral infection, as well as innate immunity involving many inducible cytokines and chemokines. Genetic factors, such as HLA haplotypes, can influence the host’s immune response. Two haplotypes have been associated ...
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Immunodeficiency in the Absence of High Viral Load in Pig-Tailed Macaques Infected with Simian Immunodeficiency Virus SIVsun or SIVlhoest
... Simian immunodeficiency virus (SIV) is known to result in an asymptomatic infection of its natural African monkey host. However, some SIV strains are capable of inducing AIDS-like symptoms and death upon experimental ...
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Cataloguing of Potential HIV Susceptibility Factors during the Menstrual Cycle of Pig-Tailed Macaques by Using a Systems Biology Approach
... ELISAs. Enzyme-linked immunosorbent assays (ELISAs) were per- formed on the same weekly specimens (10 macaques) to determine the presence of innate proteins, including kallikrein-like (KLK) peptidases (Antibodies Online, ...
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Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques.
... By animal-to-animal passage of simian/human immunodeficiency virus (SHIV) in pig-tailed macaques, we have developed a macaque model of human immunodeficiency virus type 1 (HIV-1) disease in humans. ...
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Characterization of a Macaque Recombinant Monoclonal Antibody That Binds to a CD4-Induced Epitope and Neutralizes Simian Immunodeficiency Virus
... recombinant macaque IgG1 molecule and its unique biological ...neutralizing macaque monoclonal IgG antibody, it was necessary to (i) generate macaque heavy chain immunoglobulin genes, (ii) insert ...
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