Pituitary adenylate-cyclase-activating polypeptide
Accelerated Evolution of the Pituitary Adenylate Cyclase-Activating Polypeptide Precursor Gene During Human Origin
... Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide abundantly expressed in the central nervous system and involved in regulating neurogenesis and neuronal ...
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Pituitary adenylate cyclase-activating polypeptide expression in peripheral blood mononuclear cells of migraineurs
... Pituitary adenylate cyclase-activating polypeptide (PACAP) is a member of the vasoactive intestinal pep- tide (VIP)/secretin/glucagon peptide family, which is widely expressed in humans ...
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Ventilatory and cardiovascular actions of centrally and peripherally administered trout pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) in the unanaesthetized trout
... mammals, pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are involved in cardiovascular and respiratory ...
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Transport of the pituitary adenylate cyclase-activating polypeptide across the blood-brain barrier: implications for migraine
... We performed a systematic literature search in July 2017 via PubMed to identify studies reporting original data on PACAP in relation to the BBB. The following search terms were used: pituitary adenylate ...
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Human mesenchymal stem/stromal cells suppress spinal inflammation in mice with contribution of pituitary adenylate cyclase-activating polypeptide (PACAP)
... mouse pituitary adenylate cyclase-activating polypeptide (PACAP; gene: Adcyap1) increased approximately ten fold in animals receiving hMSCs after ischemia compared with animals ...
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The pituitary adenylate cyclase–activating polypeptide is a physiological inhibitor of platelet activation
... The pituitary adenylate cyclase–activating polypeptide (PACAP) is a neuropeptide of the vasoactive intestinal peptide/secretin/glucagon ...peptide/pituitary adenylate ...
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PACAP and its role in primary headaches
... cord. Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are members of the VIP/secretin/growth hormone-releasing hormone/glucagon ...
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Neuropeptide signaling and hydrocephalus: SCO with the flow
... the pituitary adenylate cyclase–activating polypeptide (PACAP) type I (PAC1) receptor gene results in abnormal development of the SCO and vel cells, leading to congenital hydrocephalus ...
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The KATP channel in migraine pathophysiology: a novel therapeutic target for migraine
... Pituitary adenylate cyclase activating polypeptide (PACAP) is a potent endothelium independent vasodilator of vari- ous vascular beds, including cerebral arteries [44, ...
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Localization and function of VIP and PACAP in the heart
... neuropeptide pituitary adenylate cyclase-activating peptide ...insulinotropic polypeptide and growth hormone-releasing factor ...
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The git5 Gβ and git11 Gγ Form an Atypical Gβγ Dimer Acting in the Fission Yeast Glucose/cAMP Pathway
... et al., 1998 Involvement of distinct G-proteins, Gpa2 and Ras, Nocero, M., T. Isshiki, M. Yamamoto and C. S. Hoffman, 1994 in glucose- and intracellular acidification-induced cAMP signal- Glucose repression of fbp1 ...
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Solubilized myocardial adenylate cyclase: Restoration of histamine responsiveness by phosphatidylserine
... of adenylate cyclase, 2 × 10 -5 M, was virtually identical with that observed in the particulate ...of adenylate cyclase by histamine in both the solubilized and particulate ...
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Loss of high affinity cardiac beta adrenergic receptors in dogs with heart failure
... We studied the alterations in myocardial beta-adrenergic receptor-adenylate cyclase activity and muscarinic receptor density in a canine model of left ventricular (LV) failure. LV failure was characterized ...
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Studies on the Mode of Action of Cholera Toxin: EFFECTS ON SOLUBILIZED ADENYLATE CYCLASE
... of adenylate cyclase from control and toxin-treated rat livers were ...studied. Adenylate cyclase activity was measured in both particulate and solubilized form in rat liver under control ...
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High skeletal muscle adenylate cyclase in malignant hyperthermia
... biochemical marker for this myopathy has not previously been available; we found activity of adenylate cyclase and content of cyclic AMP to be abnormally high in skeletal muscle. Secondary modification of ...
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A novel role of sesamol in inhibiting NF-κB-mediated signaling in platelet activation
... of adenylate cyclase and guanylate cyclase, respectively, strongly reversed the sesamol (25 μM)-mediated inhibitory effects of IKKb phosphorylation, IBa degradation, and p65 phosphorylation ...
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Effects of cholera toxin on adenylate cyclase Studies with guanylylimidodiphosphate
... on adenylate cyclase was ...liver adenylate cyclase by cholera toxin in vivo, or by cholera toxin and NAD in homogenates, blocked the stimulatory effect of ...
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Role of adenylate cyclase, guanylate cyclase enzyme and phosphodiesterase isozyme modulation in animal models of epilepsy.
... guanylate cyclase (GC), an important transmembrane enzyme possesses certain activity in the brain, which promotes the intracellular level of cGMP, from guanosine triphosphate (GTP) (Hescheler J et ...guanylate ...
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Role of adenylate cyclase, guanylate cyclase enzyme and phosphodiesterase isozyme modulation in animal models of epilepsy.
... systems can be activated by diverse means, either by activation of enzymes that synthesize them, as is the case with the activation of cyclases that synthesize cyclic nucleotides, or by opening of ion channels to allow ...
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The Role of Cyclic AMP in the Octopaminergic Modulation of Flight Muscle in the Locust
... Effect of the adenylate cyclase activator forskolin The direct actions of the phosphodiesterase inhibitors on the DLM muscle of the locust are consistent with the idea that the octopamin[r] ...
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