pituitary tumor
Metabolic effect of 3,3',5' triiodothyronine in cultured growth hormone producing rat pituitary tumor cells Evidence for a unique mechanism of thyroid hormone action
... Physiologic levels of 3,3',5'-triiodothyronine (rT3) are generally believed to have minimal metabolic effects in the pituitary gland and other tissues. In the present studies, the regulatory role of rT3 and other ...
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Functional role of estrogen in pituitary tumor pathogenesis
... on pituitary cells ...secreting pituitary tumors derived from both male as well as female patients, as compared with other pituitary tumor types (35), and indeed may correlate with ...
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Type 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomes
... The goal of these studies was to define the rate-limiting steps in the inactivation of type 2 iodothyronine deiodinase (D2). We examined the effects of ATP depletion, a lysosomal protease inhibitor, and an inhibitor of ...
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Original Article MicroRNA-143 shows tumor suppressive effects through inhibition of oncogenic K-Ras in pituitary tumor
... important tumor suppressor in prostate cancer, pancreatic ductal adenocarcinoma and other kinds of cancers, but rarely systematically studied in pituitary ...in pituitary tumor tis- sues and ...
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A case with transient refractive change after removal of pituitary tumor
... Case presentation: A 62-year-old woman presented with blurred near vision 10 days after trans-sphenoidal surgery (TSS) for a pituitary tumor. Around the same time, she experienced intercurrent hyponatremia. ...
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Targeted expression of a human pituitary tumor–derived isoform of FGF receptor 4 recapitulates pituitary tumorigenesis
... this pituitary tumor–derived, N-terminally truncated FGFR4 cDNA, and to further exclude the possibility that alternative splicing or rearrangement was the mecha- nism responsible for this FGFR4 isoform, we ...
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Antagonism of thyroid hormone action by amiodarone in rat pituitary tumor cells
... proportional to their affinities for the receptors. We report that the benzofuran amiodarone acts as a competitive antagonist to thyroid hormone action as defined by its dose-dependent ability to (a) bind to the thyroid ...
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A study on sublabial transsphenoidal treatment of pituitary tumor under microscope with aid of endoscope
... This study was approved by the Neurosurgery Clinic of Pyongyang medical school hospital of the Kim Il Sung General University in DPRK. One hundred forty-five consecutive patients of pituitary adenomas treated ...
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Shan, Bing (2010): The novel sumoylation enhancer RSUME is implicated in pituitary tumor pathogenesis. Dissertation, LMU München: Fakultät für Biologie
... posterior pituitary gland develops by the evagination of neural tissue from the floor of the third ventricle (Mehta and Dattani ...posterior pituitary also contains glial cells called pituicytes which ...
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Original Article Expression of Eag1 K+ channel and ErbBs in human pituitary adenomas: cytoskeleton arrangement patterns in cultured cells
... or tumor suppressors and the phe- notype of pituitary tumor cells [1, 3, ...aggressive pituitary adenoma behavior [14-16, ...in pituitary adenomas [14-16, ...if pituitary ...
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Type 2 iodothyronine deiodinase is highly expressed in human thyroid
... These surprising results led us to reevaluate our concepts of the physiological role of D2. In the course of comparing D2 and D1 expression in various tissues, we found D2 mRNA and enzyme activity in the thyroid of a ...
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Beat the giant: case of a giant prolactinoma during pregnancy on cabergoline
... common pituitary tumors in women of childbearing age ...of pituitary tumors are intrasellar adenomas, while the remainder are ...rare pituitary tumor subtype associated with high serum PRL ...
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Acromegaly
... The pituitary/hypothalamic origin of these adenomas is controversial ...total tumor resection points instead to a pituitary origin ...of pituitary adenomas, isola- tion of a single causative ...
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Use of micro-positron emission tomography with <sup>18</sup>F-fallypride to measure the levels of dopamine receptor-D2 and <sup>18</sup>F-FDG as molecular imaging tracer in the pituitary glands and prolactinomas of Fischer-344 rats
... of pituitary gland cells and sinus-like ...the pituitary tumor cells have abnormal morphol- ogy, disordered structure, differed in shape and size, and exhibited nuclear atypia, with unclear nuclear ...
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Apoptotic and Necrotic Effects of Pectic Acid on Rat Pituitary GH3/B6 Tumor Cells
... To investigate whether PA induced apoptosis in pituitary tumor cells, TUNEL and PI staining to quantitate apoptosis were used in the present experiments. The fluorescent microscopic findings showed that PA ...
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Pituitary Adenomas: Early Postoperative MR Imaging After Transsphenoidal Resection
... In 13 of 67 macroadenomas, there was isoin- tensity, except for fat signal intensity in the tumor area. In these patients, this isointensity was seen as low signal intensity on T2-weighted image, sug- gestive of ...
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Results The commonest benign tumor of sellar and supra sellar region was pituitary adenomas followed
... In non tumorous, epidermal cysts and pituitary infarct were commonest lesions presenting as mass lesion in sellar-suprasellar region followed by arachnoid cyst, granulomatous hypophysitis. These results were in ...
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Decreased hypothalamic growth hormone releasing hormone content and pituitary responsiveness in hypothyroidism
... on pituitary growth hormone (GH) secretion and hypothalamic GH-releasing hormone (GRH) concentration were compared to define the mechanism of hypothyroid-associated GH ...and pituitary GH content. Cultured ...
9
Hartlmüller, Daniela (2018): The effects of temozolomide on normal and tumoral pituitary cells. Dissertation, LMU München: Medizinische Fakultät
... reduces tumor mass and has an inhibitory effect on angiogenesis, which might add to the observed good clinical outcome ...for tumor cells growing in ...
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Nonfunctioning pituitary macroadenomas : treatment and long-term follow-up
... In ons onderzoek, bij patiënten zonder postoperatieve radiotherapie, werd een goede lange-termijn tumor-controle bereikt in 89% van alle patiënten (hoofdstuk 3). Zelfs bij patiënten met tumorresidu op de ...
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