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placenta-derived stem cells

Amnion-derived stem cells: in quest of clinical applications

Amnion-derived stem cells: in quest of clinical applications

... A placenta is discarded after every live birth; objections to derive stem cells from placentae are not ...using stem cells from discarded human tissue are ultimate recycling ...

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Placenta-derived cells for acute brain injury

Placenta-derived cells for acute brain injury

... of placenta-derived stem cells for acute brain ...Infused cells can reprogram the local inflamma- tory microenvironment from detrimental to beneficial, favoring ...

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Induction of chondrogenesis of human placenta-derived mesenchymal stem cells via heparin-grafted human fibroblast derived matrix

Induction of chondrogenesis of human placenta-derived mesenchymal stem cells via heparin-grafted human fibroblast derived matrix

... mesenchymal stem cells (MSCs) contain multipotent cells and they can differentiate into bone, fat, cartilage, muscle, and neurons when induced by appropriate biological cues [16, ...blood, ...

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Improved osteogenesis and upregulated immunogenicity in human placenta-derived mesenchymal stem cells primed with osteogenic induction medium

Improved osteogenesis and upregulated immunogenicity in human placenta-derived mesenchymal stem cells primed with osteogenic induction medium

... De-MSCs cells (1 × 10 6 cells/bundle) was seeded on the collagen scaffolds and then implanted subcutane- ously in the back of nonobese diabetic/severe combined immunodeficient mouse recipients ...some ...

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Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta

Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta

... endothelial cells in vitro for 2 ...entiated cells; however, no statistical significance was found (p > ...of cells after endothelial differentiation, an immuno- staining assay [20, 21] and an ...

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Effect of Placenta Derived Mesenchymal Stem Cells in a Dementia Rat Model via Microglial Mediation: a Comparison between Stem Cell Transplant Methods

Effect of Placenta Derived Mesenchymal Stem Cells in a Dementia Rat Model via Microglial Mediation: a Comparison between Stem Cell Transplant Methods

... better stem cell delivery through intra-arterial (IA) injec- tions, however, our previous IA injection trials entailed several difficulties: considerable invasiveness involving incision through neck skin and ...

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Comparison of biological characteristics of mesenchymal stem cells derived from maternal-origin placenta and Wharton’s jelly

Comparison of biological characteristics of mesenchymal stem cells derived from maternal-origin placenta and Wharton’s jelly

... 6 cells were har- vested, and ...the cells were incubated in a water bath at 37 ...the cells were dried for 10 min with 10 % Giemsa, and then washed with distilled ...fixed cells were observed ...

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The efficacy of human placenta-derived mesenchymal stem cells on radiation enteropathy along with proteomic biomarkers predicting a favorable response

The efficacy of human placenta-derived mesenchymal stem cells on radiation enteropathy along with proteomic biomarkers predicting a favorable response

... T cells relevant to allogeneic stem cells [50] and stem cell renewal to pro- mote their regeneration [51]; changes of OTC1 (though this gene is involved in neuropathology due to deficiency ...

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Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells

Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells

... produce ATP through electron transport chain (ETC) and oxidative phosphorylation (OXPHOS) in three major nu- trients such as fatty acids, glucose, and amino acids. A “metabolic flexible” means free switch between major ...

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Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis

Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis

... The results of the current study indicate that PlaMSC- exo are partly responsible for the angiogenic effects of PlaMSC-CM in vitro and that PlaMSC-exo also enhance angiogenesis in vivo. As shown in Fig. 3a, microvesicles ...

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Human placenta-derived mesenchymal stem cells ameliorate orbital adipogenesis in female mice models of Graves’ ophthalmopathy

Human placenta-derived mesenchymal stem cells ameliorate orbital adipogenesis in female mice models of Graves’ ophthalmopathy

... Treg cells co-cultured with PMSCs significantly expanded in comparison with others with bone marrow-derived mesenchymal stem cells (BMSCs) ...the placenta could be an abundant source of ...

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Allantois and placenta as developmental sources of hematopoietic stem cells

Allantois and placenta as developmental sources of hematopoietic stem cells

... form the caudal end of the primitive streak into the exocoelomic cavity. By the stage of 6 to 8 pairs of somites (depending on individual embryos), the allantois contacts the chorionic plate and attaches to it. In the ...

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Differential ability of MSCs isolated from placenta and cord as feeders for supporting ex vivo expansion of umbilical cord blood derived CD34+ cells

Differential ability of MSCs isolated from placenta and cord as feeders for supporting ex vivo expansion of umbilical cord blood derived CD34+ cells

... P-MSCs placenta-derived mesenchymal stem cells, C-MSCs cord-derived mesenchymal stem cells, HSCs hematopoietic stem cells, CFU-F colony forming ...

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Dynamic Regulation of miRNA Expression by Functionally Enhanced

Dynamic Regulation of miRNA Expression by Functionally Enhanced

... miRNA profiling of invaded naïve placenta-derived mesenchymal stem cells (PD-MSCs). 433[r] ...

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Repair of Spinal Cord Injury; Mesenchymal Stem Cells as an Alternative for Schwann Cells

Repair of Spinal Cord Injury; Mesenchymal Stem Cells as an Alternative for Schwann Cells

... adipose-derived stem cells (ADSCs) as mesenchymal stem cells (MSCs), which also derived from peripheral blood, placenta and umbilical cord, the lung, and the heart, are ...

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Antitumor activity of pluripotent cell-engineered vaccines and their potential to treat lung cancer in relation to different levels of irradiation

Antitumor activity of pluripotent cell-engineered vaccines and their potential to treat lung cancer in relation to different levels of irradiation

... Cancer stem cells (CSCs) are critical for tumor initiation/maintenance and recurrence or metastasis, so they may serve as a potential therapeutic ...on placenta- derived mesenchymal ...

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VCAM-1+ placenta chorionic villi-derived mesenchymal stem cells display potent pro-angiogenic activity

VCAM-1+ placenta chorionic villi-derived mesenchymal stem cells display potent pro-angiogenic activity

... This study was approved by the Ethical Committee and the Institutional Review Board of the Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China. All volunteers provided informed consent. ...

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Is Adipocyte Differentiation the Default Lineage for Mesenchymal Stem/Progenitor Cells after Loss of Mechanical Loading? A Perspective from Space Flight and Model Systems

Is Adipocyte Differentiation the Default Lineage for Mesenchymal Stem/Progenitor Cells after Loss of Mechanical Loading? A Perspective from Space Flight and Model Systems

... on cells of the microcirculation are well ...that cells such as mast cells often co-localize with nerves and are capable of amplifying neural signals (reviewed in ...resident cells may be a ...

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Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease

Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease

... IBD is a general term used to describe an idiopathic disorder that can be subdivided based on histopathology findings, i.e., granulomatous meningoencephalomyelitis (GME), necrotizing meningoencephalitis (NME), and ...

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Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies

Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies

... neural stem cells that had been differentiated from human iPSCs into immunodeficient rats 2 weeks after a C5 half-cut ...somatic cells may take more than 1 year ...

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