Planar polarity
Principles of planar polarity in animal development
... and planar polarity is indisputable, the nature of this relationship is still unclear (for reviews, see Fischer and Pontoglio, 2009; Wallingford, ...of planar polarity, as two mutations that ...
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Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity
... antagonistically to influence multiple aspects of tissue morphogenesis. We find that Fat1 and Fat4 cooperate during mouse development to control renal tubular elongation, cochlear extension, cranial neural tube formation ...
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Cell interactions and planar polarity in the abdominal epidermis of Drosophila
... affect polarity in the same way in both A and P. We selected four polarity genes that strongly affect polarity, frizzled (fz), prickle (pk), Van gogh/strabismus (Vang/stbm) and starry night/flamingo ...
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Structure–Function Dissection of the Frizzled Receptor in Drosophila melanogaster Suggests Different Mechanisms of Action in Planar Polarity and Canonical Wnt Signaling
... in planar polarity but gave rise to Fz proteins still able to recruit Dsh to ...in planar polarity signaling being to recruit Dsh, although we also note that in some cases a failure to recruit ...
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The planar polarity pathway promotes coordinated cell migration during Drosophila oogenesis
... for planar polarity pathway function for efficient convergent extension movements, it is a good candidate to coordinate the collective migration of cells in other ...
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A link between planar polarity and staircase like bundle architecture in hair cells
... ’ planar cell polarity (PCP) proteins that are asymmetrically enriched at cell-cell junctions ensure uniform bundle orientation across HCs (May-Simera and Kelley, ...that planar asymmetry of the ...
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Integrating planar polarity and tissue mechanics in computational models of epithelial morphogenesis
... 12, 56011 447 •• This computational study couples a model of polarisation of Rho-kinase, myosin 448 and Bazooka with a vertex model to understand the interplay between planar polarity 44[r] ...
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Planar polarity of the extraembryonic epithelia in the preimplantation porcine conceptus
... the planar polarity of pig T and E epithelial cells observed by scanning and transmission electron microscopy and by immunofluorescence, using many cytochemical markers of such ...the polarity and ...
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dachsous and frizzled contribute separately to planar polarity in the Drosophila ventral epidermis
... Cells that comprise tissues often need to coordinate cytoskeletal events to execute morphogenesis properly. For epithelial tissues, some of that coordination is accomplished by polarization of the cells within the plane ...
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Centriole planar polarity assessment in Drosophila wings
... and planar polarity effector) complex, formed in part by Inturned (Intu), Fuzzy (Fuz) and WD repeat containing planar cell polarity effector (Wdpcp) (Adler and Wallingford, 2017; Park et ...
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Regulation of cytoskeletal organization and junctional remodeling by the atypical cadherin Fat
... regulates planar polarized junctional localization and remodeling, which in turn influences cell ...denticle planar polarity are correctly established in dachs mutants, indicating that Dachs is not ...
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Shaping the mammalian auditory sensory organ by the planar cell polarity pathway
... defined planar polarity both in the intrinsically polarized structure of each individual cell and in the arrangement of different cells relative to each other within the group ...The planar ...
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Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo
... mutants. Planar polarity is required for the posterior positioning of cilia on cells in the mouse node, which is essential for the initiation of left-right ...in planar polarity in the double ...
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Long-term preservation of planar cell polarity in reversed tracheal epithelium
... There is a question of whether it is possible to adjust PCP afterwards in regenerated tracheal epithelium once acquired. There have been no reports on whether tra- cheal epithelium can acquire or change PCP according to ...
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Planar cell polarity in moving cells: think globally, act locally
... Although PCP in epithelial cells is characterized by the stable asymmetric localization of Fzd and Vangl complexes to opposite sides of cells, live imaging of fluorescent PCP fusion proteins has demonstrated that these ...
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Gpr125 modulates Dishevelled distribution and planar cell polarity signaling
... Functional interactions between Gpr125 and PCP components and planar polarity defects of Gpr125 overexpressing gastrulae are consistent with a role of Gpr125 in modulating Wnt/PCP signaling. As Dvl membrane ...
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The cadherin Fat2 is required for planar cell polarity in the Drosophila ovary
... cell polarity is an important characteristic of many ...of planar cell polarity requires the core planar cell polarity genes and two cadherins, Fat and ...during planar cell ...
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Is left right asymmetry a form of planar cell polarity?
... because planar polarity is thought of as being a global property of tissue structure, which requires asymmetries to be established in cells located far from each other (Zallen, ...Because planar ...
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The abdomen of Drosophila: does planar cell polarity orient the neurons of mechanosensory bristles?
... of planar polarity is essential to the organisation of epithelia and is likely to operate from the beginning of development; indeed, there is evidence that PCP acts in the early embryo [36-38] and ...
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Twinstar, the Drosophila homolog of cofilin/ADF, is required for planar cell polarity patterning
... The PCP pathway is not a simple linear biochemical cascade as there is clear evidence for multiple branches. For example, after Fz relocalizes to the distal end of the cell, it regulates the non-muscle myosin regulatory ...
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