Plasma Proteomics
A neural network approach to multi biomarker panel discovery by high throughput plasma proteomics profiling of breast cancer
... based plasma proteomics profiling technique is a promising technology platform to study candidate protein biomarkers for early detection of ...of proteomics profiles challenging. Developing ...
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<p>Pilot-Scale Study Of Human Plasma Proteomics Identifies ApoE And IL33 As Markers In Atopic Asthma</p>
... label-free plasma proteomics, cytokine pro- fi ling was done for IL4, IL5, IL13, and IL33 from blood- plasma ...IL33, plasma levels of the cytokine were found to be signi fi - cantly upregulated ...
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A novel workflow combining plaque imaging, plaque and plasma proteomics identifies biomarkers of human coronary atherosclerotic plaque disruption
... gun proteomics, we compared plasma samples taken at baseline and at 5 min to capture the earliest changes detectable in ...culation. Plasma samples for each group were pooled for subsequent analysis, ...
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iTRAQ plasma proteomics analysis for candidate biomarkers of type 2 incipient diabetic nephropathy
... Haptoglobin (Hp) is a circulating glycoprotein that is mainly synthesized in the liver [16], which reduces the oxidative ability of heme iron by scavenging free hemoglobin [17]. Hp has been identified as a candidate ...
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Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain
... AD plasma samples (Additional file 1: Figure S1A), leading to the recognition of a number of biological pathways and proteins potentially affected in the disease ...and Plasma protease C1 inhibi- tor [60], ...
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Identification of novel biomarker and therapeutic target candidates for acute intracerebral hemorrhage by quantitative plasma proteomics
... depleted plasma from ICH or normal samples were added into 400 μl of phosphate- buffered saline, 500 μl of ice-cold acetone, 10% trichlo- roacetic acid (TCA) solution, and then precipitated at −20 ...
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A large, consistent plasma proteomics data set from prospectively collected breast cancer patient and healthy volunteer samples
... human plasma LC-MS/MS spectral library we have created from MS/MS analyses of nearly 150 discrete human plasma samples; additional and subsequent targeted LC-MS/MS analysis is often not required to identify ...
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HIP2: An online database of human plasma proteins from healthy individuals
... human plasma proteome data into their ...The Plasma Proteome Database (PPD) provides a web interface and is geared for providing detailed functional annotations of 3,778 distinct proteins based on data ...
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Exploring the Human Seminal Plasma Proteome: An Unexplored Gold Mine of Biomarker for Male Infertility and Male Reproduction Disorder
... Seminal plasma is a complex body fluid, con- taining a large diversity of ...seminal plasma; however, possibly up to 10,000 proteins can be expressed in the seminal ...Seminal plasma is an excellent ...
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Adapting extracellular matrix proteomics for clinical studies on cardiac remodeling post-myocardial infarction
... for plasma proteomics experiments to improve both reproducibility and ...Human Plasma Proteome Project, evaluation of serum and plasma samples collected under a variety of condi- tions showed ...
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Comparative proteomics and glycoproteomics of plasma proteins in Indian visceral leishmaniasis
... of proteomics, efforts have been made to identify and categorize the plasma proteins because of their potential utility as disease biomarkers, in thera- peutic monitoring, and in understanding host ...
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Proteomic analysis of human plasma in chronic rheumatic mitral stenosis reveals proteins involved in the complement and coagulation cascade
... undertook plasma proteomics of human subjects suffering from Rheumatic Mitral Stenosis (n = 6) and Control subjects (n = ...Six plasma samples, three each from the control and patient groups were ...
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Proteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus
... This proteomics approach revealed various putative virulence factors, including active type VI secretion systems and effectors with virulence toxin domains; however, these type VI secretion systems were not ...
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Comparative proteomics analysis of Spodoptera frugiperda cells during Autographa californica multiple nucleopolyhedrovirus infection
... Comparative proteomics analysis of Spodoptera frugiperda cells during Autographa californica multiple nucleopolyhedrovirus infection RESEARCH Open Access Comparative proteomics analysis of Spodoptera[.] ...
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Comparative Community Proteomics Demonstrates the Unexpected Importance of Actinobacterial Glycoside Hydrolase Family 12 Protein for Crystalline Cellulose Hydrolysis
... The genesis of this study was to test the reproducibility of com- munity adaptation to growth on microcrystalline cellulose. A pre- vious set of adaptation experiments on microcrystalline cellulose and wheat arabinoxylan ...
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Oolemmal proteomics – identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane
... Separation of surface-labeled biotinylated egg proteins followed by avidin blotting was utilized to identify sur- face-labeled proteins. For these experiments, proteins from 800 zona-free biotinylated mouse eggs were ...
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Plasma protein profiling of Mild Cognitive Impairment and Alzheimer’s disease using iTRAQ quantitative proteomics
... the plasma of MCI and AD sub- jects in comparison with cognitively normal ...immunodepleted plasma samples from amnestic single and multiple do- main MCI (aMCI), nonamnestic single and multiple do- main MCI ...
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BioAfrica's HIV 1 Proteomics Resource: Combining protein data with bioinformatics tools
... online proteomics resource that integrates bioinformatics with the latest information on HIV-1 protein structure, gene expression, post-transcriptional/post-translational modification, functional activity, and ...
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Plasma Membrane Proteomics Identifies Biomarkers Associated with MMSET Overexpression in T(4;14) Multiple Myeloma
... The 1365 amino acid MMSET protein contains a SET domain that is found in many histone methyltransferases (HMTs) and determines their enzymatic activity [10]. Recently MMSET has been shown to have histone ...
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Male Infertility, Precision Medicine and Systems Proteomics
... PM and male infertility (Antioxidant therapy): About 20% of couples are estimated to be infertile (38). Infertility is a disease that can have a negative effect on the mental health of couples. Male factor infertility ...
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