Plasminogen activators (PAs)
Expression of plasminogen activators in preimplantation rat embryos developed in vivo and in vitro
... pregnancy. Plasminogen activators (PAs) have been implicated in mammalian fertilization, early stages of development and embryo ...reduced PAs activity may lead to ...of PAs in ...
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Sites of synthesis of urokinase and tissue type plasminogen activators in the murine kidney
... of plasminogen activators ...(t-PA) plasminogen activators and of their mRNAs in developing and adult mouse ...of PAs suggests that both enzymes may be implicated in the maintenance of ...
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Support vector machine (SVM) based multiclass prediction with basic statistical analysis of plasminogen activators
... domain activators, since they have the functional capacity to convert plasminogen to active plasmin by cleaving the Arg-Val bond on the single-chain plasminogen to release two plasmin ...indirect ...
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Effect of urokinase antiserum on plasminogen activators: demonstration of immunologic dissimilarity between plasma plasminogen activator and urokinase
... Antiserum against purified human urokinase was produced by immunization of Hartley strain guinea pigs. The antiserum was capable of neutralizing the plasminogen activator activity of the antigen and of native ...
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Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activator
... fibrinolysins; plasminogen activators (PAs) or plasmin, have been applied pre-clinically and clinically, but it is unclear as to which option or class of agents is ...
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The Enzymatic Dissolution Of Experimental Arterial Thrombi in the Dog by Trypsin, Chymotrypsin and Plasminogen Activators
... Recent reports have appeared on the successful liquefaction of intravascular clots in rabbit ear veins by the intravenous infusion of large amounts of streptokinase 1; the lysis of venou[r] ...
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The role of plasminogen activators in neoplasia and inflammatory lesions of the human intestine
... V CHAPTER 2 MATERIALS AND METHODS 37 CHAPTER 3 MONOCLONAL ANTIBODIES INHIBITORY TO 65 HUMAN PLASMIN: DEFINITIVE DEMONSTRATION OF A ROLE FOR PLASMIN IN ACTIVATING THE PROENZYME OF UROKINA[r] ...
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The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis
... express plasminogen activators (47, ...with plasminogen could rely on local activation in the CNS and start a pro- teolytic process that results in neurologic ...activated PAS could supply the ...
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Observational study on pharmacoinvasive strategy and primary angioplasty in a tertiary care centre in acute myocardial infarction patients
... As compared to STK, administration of tissue plasminogen activators resulted in reduction of disabling stroke /death in nine out of one thousand patients treated, with a 0.2% absolute ex[r] ...
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Isolation from human plasma of a plasminogen activator identical to urinary high molecular weight urokinase
... plasmatic plasminogen activators (PA) can be demonstrated after sodium dodecyl sulfate polyacrylamide gel electrophoresis of plasma freshly collected from resting volunteers, followed by transfer of the ...
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Degradation of Human Fibrinogen by Plasma α2 Macroglobulin Enzyme Complexes
... of plasminogen activators to plasma induced an increase in the N-a-tosyl-l-arginine methyl ester HCl esterase and fibrinogenolytic activity associated with a 2 -macroglobulin purified from this plasma, ...
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PLASMINOGEN ACTIVITY AND INHIBITORS IN NORMAL LATE PREGNANCY POSTPARTUM AND IN THE POSTNATAL PERIOD
... Plasminogen activators, measured in blood samples taken from pregnant women, show a definite dependence on the progression of pregnancy, increasing with gestation and returning to normal levels ...
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Interaction between plasminogen activator inhibitor type 1 (PAI 1) bound to fibrin and either tissue type plasminogen activator (t PA) or urokinase type plasminogen activator (u PA) Binding of t PA/PAI 1 complexes to fibrin mediated by both the finger and the kringle 2 domain of t PA
... urokinase-type plasminogen activator (u-PA). This reaction is controlled by plasminogen activator inhibitor type 1 (PAI-1) that is either present in plasma or bound to fibrin, present in a ...activate ...
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Arsenic Removal from Mine Tailings for Recycling via Flotation
... In this study, we propose a fl otation process to remove the arsenic from Samkwang mine tailings in South Korea, which contained a high arsenic content, in order to render them suitable for recycling. In order to maximize ...
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Transfusion reactions after transfusion of platelets stored in PAS-B, PAS-C, or plasma: a nationwide comparison
... In PAS-B platelets, shown in table 3, the transfusions with older (4 to 5 day old) units were associated with more allergic reactions compared to the fresher (1 to 3 day old) units, odds ratio ...older ...
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Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface
... of plasminogen and tissue plasminogen activa- tor with native and activated platelets, to determine the amount of plasmin generated by various activators in the presence of platelets, and the ability ...
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De programmatische aanpak stikstof: komt de PAS van pas? (BR 2015/48)
... Uit dit artikel volgt dat het bevoegd gezag, dat norma- liter ontwikkelingsruime zou toekennen, in overeenstem- ming met het bevoegd gezag dat het beheerplan vaststelt voor het betrokken Natura 2000-gebied, kan ...
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Study of the sites of plasminogen molecule which are responsible for inhibitory effect of Lys-plasminogen on platelet aggregation
... obtained plasminogen forms, kringles K1-3, K4 and K5 were homogeneous according to electrophoresis data in PAAG ...of plasminogen had no spontaneous plasmin ...
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Fibrinogen Activates the Capture of Human Plasminogen by Staphylococcal Fibronectin Binding Proteins
... ABSTRACT Invasive bacterial pathogens can capture host plasminogen (Plg) and al- low it to form plasmin. This process is of medical importance as surface-bound plas- min promotes bacterial spread by cleaving ...
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Modularity of eukaryotic transcription activators
... such activators work; provided a powerful tool for the analysis of other gene-activating and - repressing functions; laid the basis for the development of the two-hybrid system for detecting protein-protein ...
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