Plasmodium falciparum 3D7.
EVALUATION OF IN VITRO ANTIMALARIAL ACTIVITY OF CALOTROPIS GIGANTIA AND CITRUS AURINTOFOLIA FLOWER EXTRACT AGAINST PLASMODIUM FALCIPARUM 3D7
... In the present investigation flowers of Citrus aurantifolia (Christm.) and Calotropis gigantia were tested against Plasmodium falciparum 3D7 strain by in vitro method. Both these plants are widely ...
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Identification and characterization of DNA endonucleases in Plasmodium falciparum 3D7 clone
... DNA endonucleases are a type of enzymes that hydro- lyse internal phosphodiester bonds, which exist in DNA strands. DNase I is a DNA-specific enzyme that was dis- covered in the cells of spleen, liver and digestive ...
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Antimalarial efficacy of Pongamia pinnata (L) Pierre against Plasmodium falciparum (3D7 strain) and Plasmodium berghei (ANKA)
... P. falciparum: Plasmodium falciparum; PBS: Phosphate buffered saline; PCV: Packed cell volume; RBC: Red blood cells; RPMI medium: Roswell park memorial institute medium; UV: Ultra violet; WHO: World ...
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Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts
... and amplification of the parasites a sufficiently high homogeneity of the cytoadherent phenotype is obtained which then permits functional or transcript analysis. The CHO cell lineages are especially convenient since ...
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Effect of Metabolite Extract of Streptomyces hygroscopicus subsp. hygroscopicus on Plasmodium falciparum 3D7 in Vitro
... of Plasmodium morpholog- ical development and reduced parasite levels in vivo ...P. falciparum, the proteasome subunit β5 of core proteasome shown to be present in the cytoplasm and nucleus of blood stage ...
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A bioinformatics approach for homology modeling and binding site identification of triosephosphate isomerase from Plasmodium falciparum 3D7
... P. falciparum might be of undoubted value LQGHVLJQLQJQHZVWUDWHJLHVIRUWKHUDSHXWLFLQWHUYHQWLRQ 7ULRVHSKRVSKDWHLVRPHUDVHLVDGLPHULFJO\FRO\WLFHQ]\PH ZKLFKFDWDO\]HVWKHLVRPHUL]DWLRQRI GJO\FHUDOGHK\GH ...
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Sub grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non coding regions
... basis [18,19,29]. We have synthesised the available information and suggest a somewhat different division of the var genes into three major groups (A-C) and two inter- mediate groups (B/A and B/C), which represent ...
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Molecular-docking study of malaria drug target enzyme transketolase in Plasmodium falciparum 3D7 portends the novel approach to its treatment
... The QMEAN scoring function estimates the geometrical aspects of a protein structure by a composite function of six different structural descriptors; a torsion angle potential over three consecutive amino acids to analyze ...
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Acquired Antibodies to Merozoite Antigens in Children from Uganda with Uncomplicated or Severe Plasmodium falciparum Malaria
... of Plasmodium falciparum 3D7 and FC27 (MSP2-3D7/ FC27), and apical membrane antigen 1 (AMA1) in patients with uncomplicated malaria by enzyme-linked immunosorbent assay (ELISA) but no ...
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Novel aminoalkylated chalcone: Synthesis, biological evaluation, and docking simulation as potent antimalarial agents
... against Plasmodium falciparum 3D7 strain (sensitive chloroquine) according to the method of Rieckmann et ...P. falciparum were calculated by counting the number of infected erythrocytes for ...
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Actinomycin Used as A Potent Inhibitor for Malaria Parasite Plasmodium Falciparum
... the Plasmodium falciparum is creating a worsened situation for mankind, and there were around 214 million new cases of malaria in 2015 (range 149-303 million) all over the ...on Plasmodium ...
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Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents
... Results: The present work involves the design and synthesis of some novel acyl hydrazone based molecular hybrids of 1,4-dihydropyridine and pyrazole (5a–g). These molecular hybrids were synthesised by condensation of ...
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Collaborative intelligence and gamification for on line malaria species differentiation
... Additional file 1. (a–e) Tutorial images used before beginning each level showing the characteristic shape and size of each malaria specie in the different levels of the game: a) P. falciparum, b) P. vivax, c) P. ...
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Prevalence of drug resistance associated mutations in Plasmodium vivax against sulphadoxine pyrimethamine in southern Pakistan
... It is underlined that the aim of the study was to pro- vide molecular epidemiological data on frequency distri- bution of pvdhfr-pvdhps haplotypes so that data on prevalent SP resistant alleles could be reported. Neither ...
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Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa Pun District, Northern Kayin State, Myanmar
... This was an open label non-randomized trial designed to evaluate the association between the efficacy of arte- misinin against P. falciparum malaria (i.e. parasite clear- ance) and k13 mutations using the same ...
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Plasmodium falciparum histidine rich protein 2 diversity and the implications for PfHRP 2: based malaria rapid diagnostic tests in Ghana
... In some facilities in Ghana, where microscopy is una- vailable, malaria is treated based on RDT results. It is thus very important to monitor the accuracy of RDT results as well as identify factors that affect the ...
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Submicroscopic Plasmodium prevalence in relation to malaria incidence in 20 villages in western Cambodia
... the probable source of infection and could help deter- mine the risk of infection within individual villages. Even in villages with indigenous transmission, strategies to screen or treat sub-microscopic malaria in the ...
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Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation
... P. falciparum, ubiquitination (27) and sumoylation (28, 29) appear to serve as important regulators of stress ...P. falciparum stress response as a target for ...
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Plasmodium Falciparum Infections among Individuals with Different Abo and Rhesus Blood Groups Attending Kipkelion and Fort-Ternan Hospitals in Kericho County, Kenya
... P. falciparum infections with its association with ABO and Rhesus blood group should be done before a more definite statement on the apparent trend could be made (Ilozumba and Uzozie, ...
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Molecular markers of anti malarial drug resistance in Central, West and East African children with severe malaria
... The copy number of the pfmdr1 was successfully deter- mined and results were available for 285 isolates. Two isolates, one each in Lambaréné and Kisumu, were removed from the analysis because of inconsistent results. The ...
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