platelet-derived growth factor
Induction of sustained expression of proto oncogene c fms by platelet derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon gamma and macrophage colony stimulating factor in human aortic medial smooth muscle cells
... of platelet-derived growth factor (PDGF)-BB and either epidermal growth factor (EGF) or fibroblast growth factor (FGF) induced high expression of c-fms in normal ...
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Chemotaxis of monocytes and neutrophils to platelet derived growth factor
... The platelet-derived growth factor (PDGF) is shown to be chemotactic for monocytes and ...epidermal growth factor shows no chemotactic activity for inflammatory cells at ...
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Platelet derived growth factor in idiopathic pulmonary fibrosis
... several growth factors including platelet-derived growth factor ...tissues derived from five patients with idiopathic pulmonary fibrosis (IPF) and from four control individuals ...
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Effects of platelet derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat storing cells
... of platelet-derived growth factor (PDGF), epidermal growth factor (EGF), transforming growth factor (TGF)-alpha and TGF-beta, and basic fibroblast growth ...
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Origin of platelet derived growth factor in megakaryocytes in guinea pigs
... Growth factor activity, as determined by the stimulation of [3H]thymidine incorporation into the DNA of quiescent 3T3 cells in culture, was found in lysates of guinea pig platelets and ...significant ...
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The role of platelet derived growth factor in the development of mouse molars
... Int J De, MiDI 39 939 945 (1995) 939 Original Arlie/I' The role of platelet derived growth factor in the development of mouse molars JAN CoCo HU", CHUHUA ZHANG' and HAROLD C SLAVKIN2 IDepartment of Pe[.] ...
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Platelet derived growth factor inhibits bone regeneration induced by osteogenin, a bone morphogenetic protein, in rat craniotomy defects
... Platelet-derived growth factor (PDGF) is a potent moderator of soft tissue repair through induction of the inflammatory phase of repair and subsequent enhanced collagen ...
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Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential
... with platelet-derived growth factor (PDGF) stimulated the secretion of EVs, changed their protein composition and enhanced the angiogenic ...
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Coexpression of phosphotyrosine containing proteins, platelet derived growth factor B, and fibroblast growth factor 1 in situ in synovial tissues of patients with rheumatoid arthritis and Lewis rats with adjuvant or streptococcal cell wall arthritis
... Fibroblast growth factor (FGF)-1 and PDGF-B-like factors have been implicated in the pathobiology of RA and animal models of this disease. Since the receptors for FGF-1 and PDGF are tyrosine kinases, we ...
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Platelet-derived growth factor and its receptors in retinal development
... To m y knowledge, th is is th e first tim e a tru n c a te d g ro w th factor receptor of th is type h as been successfully delivered in vivo. T his approach m ight be of g en eral use; o th er tru n c a te d ...
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Tissue localization of beta receptors for platelet derived growth factor and platelet derived growth factor B chain during wound repair in humans
... A concordant increase in PDGF receptor mRNA was detected by in situ hybridization in healing wounds; PDGF receptor mRNA expression was observed in cells located in the proliferating gran[r] ...
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Structural optimization and evaluation of novel 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole derivatives as potential VEGFR-2/PDGFRβ inhibitors
... epidermal growth factor; FGF: fibroblast growth factor; VEGF: vascular endothelial growth factor; PDGF: platelet‑derived growth factor; RCC: renal ...
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Wound Treatment Using Growth Factors
... with growth factors is an effective method to promote wound ...Several growth factors have been used in wound treatment, including basic fibroblast growth factor (bFGF) discovered in the ...
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The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children
... endothelial growth factor (VEGF), a dimeric 46-kDa gly- coprotein, is an endothelial cell-specific, multifunctional ...[6,7]. Platelet-derived growth factor (PDGF) has angiogenic ...
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Nintedanib: evidence for its therapeutic potential in idiopathic pulmonary fibrosis
... the platelet-derived growth factor (PDGF)/PDGF receptor pathway is thought to play a critical role in fibrogenesis of the ...Other growth factors, including fibroblast growth ...
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Caries Induced FGF 2 Expression in Human Dental Pulp
... regulatory factor in the control of vascular permeability and angiogenesis (Ferrara et ...endothelial growth factor is originally a basic 45-kDa heparin-binding ...and Platelet derived ...
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Safety study: is there a pathologic IGF-1, PDGF and TGF-ß cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?
... like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients with the gold ...
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Platelet Rich Plasma Intra Articular Injection for Chronic Synovitis Treatment in Patients with Haemophilia One Year Follow Up
... [5]. Platelet-rich plasma (PRP) is used to stimulate healing of the joint and provide symptomatic relief ...with growth factors and proteins used in joint homeostasis, healing mechanisms and tissue ...
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Tumor-induced osteomalacia due to a recurrent mesenchymal tumor overexpressing several growth factor receptors
... PDGFRA, platelet derived growth factor type A; PDGFRB, platelet-derived growth factor receptor type B, VEGFR3, vascular endothelial growth factor ...
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Mesenchymal stem cells in the osteosarcoma microenvironment: their biological properties, influence on tumor growth, and therapeutic implications
... Cancers require a sufficient energy supply for develop- ment. What’s more, they have to escape autologous im- mune surveillance that is usually initiated by NK cells and CD8 + T cells. Tumor cells are able to secret ...
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