platelet-derived growth factor-2
Platelet derived growth factor in idiopathic pulmonary fibrosis
... specimens with IPF but not in the four control specimens without IPF. The expression of c- sis mRNA was localized primarily in the epithelial cells. Invading alveolar macrophages also expressed c-sis mRNA. The expression ...
11
Nintedanib: evidence for its therapeutic potential in idiopathic pulmonary fibrosis
... the platelet-derived growth factor (PDGF)/PDGF receptor pathway is thought to play a critical role in fibrogenesis of the ...Other growth factors, including fibroblast growth ...
10
Platelet Rich Plasma Intra Articular Injection for Chronic Synovitis Treatment in Patients with Haemophilia One Year Follow Up
... [5]. Platelet-rich plasma (PRP) is used to stimulate healing of the joint and provide symptomatic relief ...with growth factors and proteins used in joint homeostasis, healing mechanisms and tissue ...
6
Original Article The overexpression of PDGF-BB and its receptor is correlated with lymphatic metastasis in patients with non-small cell lung cancer
... prognostic factor for human ...multiple growth factors. Platelet-derived growth factor-BB (PDGF-BB) and platelet-derived growth factor receptor-β ...
8
Neovascular age-related macular degeneration: intraocular inflammatory cytokines in the poor responder to ranibizumab treatment
... cytokine/Angiogenesis/Growth factor and a Cardiovascular Magnetic Bead Panel Immunology Multiplex assay (EMD Millipore, Billerica, MA, ...IL-17A, platelet-derived growth ...
9
Caries Induced FGF 2 Expression in Human Dental Pulp
... regulatory factor in the control of vascular permeability and angiogenesis (Ferrara et ...endothelial growth factor is originally a basic 45-kDa heparin-binding ...and Platelet derived ...
89
Platelet derived growth factor inhibits bone regeneration induced by osteogenin, a bone morphogenetic protein, in rat craniotomy defects
... presented subcutaneous masses superior to the defect sites. The masses, comprised of serosanguinous fluid encapsulated by fibrous connective tissue, were larger and occurred more frequently in rats treated with 200 ...
10
Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential
... bone-marrow derived MSCs contribute to tissue remodeling after injury ...EVs derived from ASCs that may represent a suitable source of adult stem cells for regenerative medi- ...angiogenic growth ...
12
Antiangiogenic effects in patients with progressive desmoplastic small round cell tumor: data from the French national registry dedicated to the use of off-labeled targeted therapy in sarcoma (OUTC’s)
... endothelial growth factor receptors (VEGFR) 1–3, c-KIT, and the platelet-derived growth factor receptors (PDGFR) alpha and beta, and has been approved for advanced soft tissue ...
7
An Essential Role for Macrophage Migration Inhibitory Factor (MIF) in Angiogenesis and the Growth of a Murine Lymphoma
... (IL-1), IL-2, hematopoietic colony-stimulating factors (CSFs), platelet-derived growth factor (PDGF), and transforming growth factor (31 (TGF-j31) each can act as an autocrine growth fac[r] ...
11
<p>Genetic Association of <em>SH2B1</em> Gene Polymorphisms in Jordanian Arab Patients with Type 2 Diabetes Mellitus</p>
... homology 2 B adapter protein 1 (SH2B1) gene and its polymorphisms have a major role in developing ...leptin, platelet-derived growth factor (PDGF), Glial cell-derived ...
10
Effects of platelet derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat storing cells
... of growth curves revealed a similar pattern of potency of the growth ...other growth factors together with PDGF by inflammatory cells represents a potent potential stimulus for FSC proliferation in ...
9
Expressions of Growth Factors in Autologous Derived Platelet-Rich Plasma and Platelet-Poor Plasma; Implication for Tissue Reparation and Wound Healing
... each factor. Any growth factor present was bound by the immobilized ...each growth factor was added to the ...bound growth factor in the first ...
7
PDGF/PDGFR effects in osteosarcoma and the “add-on” strategy
... Because PDGF acts as a potent mitogen in several osteosarcoma cell lines [55, 56] and patient-derived cell cultures [44], the inhibition of the PDGF pathway results in a reduction of cell proliferation due to cas- ...
9
Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers
... The guanylyl cyclase-coupled receptors include natriuretic peptide, nitric oxide, carbon monoxide and enterotoxin receptors. The binding of the ligand to the extracellular domain of its receptor leads to intracellular ...
12
Neuron Like Differentiation of Bone Marrow Derived Mesenchymal Stem Cells
... by growth factors, such as epidermal growth factor (EGF), hepatocyte growth factor (HGF), and vascular endothelial growth factor ...with growth factors, the shapes ...
12
The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children
... We have shown that low plasma VEGF, PDGF, FGF, and Ang-1 concentrations are associated with an unfavorable outcome in children with severe bacterial infection, the association being independent of confounding factors in ...
11
<p>Treatment of recurrent myopic macular hole using membrane of plasma rich in growth factors</p>
... In our case report, we describe a patient with myopic MH, who had not responded to PPV surgery with ILM peeling; a second surgery was carried out with an extension of the ILM peeling margins, and with a PRGF membrane ...
5
Chemotaxis of monocytes and neutrophils to platelet derived growth factor
... The platelet-derived growth factor (PDGF) is shown to be chemotactic for monocytes and ...epidermal growth factor shows no chemotactic activity for inflammatory cells at ...
5
Tissue localization of beta receptors for platelet derived growth factor and platelet derived growth factor B chain during wound repair in humans
... A concordant increase in PDGF receptor mRNA was detected by in situ hybridization in healing wounds; PDGF receptor mRNA expression was observed in cells located in the proliferating gran[r] ...
12