platelet (or brain) type
A synthetic peptide derived from the sequence of a type I collagen receptor inhibits type I collagen mediated platelet aggregation
... the type I col- lagen–induced platelet aggregation and the release of ATP in a dose-dependent ...purified platelet 65-kD protein. The peptide does not react with platelet type III ...
7
Platelet function following induced hypoglycaemia in type 2 diabetes
... on platelet function using either insulin stress test [7] or hyperinsulinaemic hypoglycaemic clamps ...with type 1 diabetes or healthy controls and showed increased platelet aggregation [7]; or ...
23
Platelet aggregation responses in type 2 diabetic patients
... with Type 2 ...with Type 2 DM and forty-eight healthy indivi- duals (control group; 22 male, 26 female) were included in this ...study. Platelet aggregation was determinated with Chorono-log 500 ...
5
Bleeding Time (BT), Clotting Time (CT), Platelet Count and Mean Platelet Volume (MPV) in Type 2 Diabetes Mellitus- A case control study
... %. Type 2 DM accounts for about 80% of ...increased platelet activity is emphasized to play a role in the development of vascular complications of this metabolic ...disorder. Platelet volume, a ...
6
Expression of the phenotypic abnormality of platelet type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment
... The platelet GP Ib-IX receptor supports platelet adhesion and activation by binding to vWf in the exposed subendothelial ...in platelet-type or pseudo-von Willebrand disease and has a ...
6
Low shear stress can initiate von Willebrand factor dependent platelet aggregation in patients with type IIB and platelet type von Willebrand disease
... by platelet membrane glycoprotein (GP) IIb-IIIa and fibrinogen, whereas aggregation induced by high shear stress (108 dyn/cm2) requires the binding of von Willebrand factor (vWF) to both GPIb-IX and GPIIb-IIIa ...
5
Association of mean platelet volume with incident type 2 diabetes mellitus risk: the Dongfeng–Tongji cohort study
... between platelet activity and type 1 diabetes mellitus (T1DM) found that platelet activation did not precede the devel- opment of microvascular complications in T1DM ...
8
A review of relationship between platelet indices and microvascular complications in type 2 diabetic patients
... Since platelet act as a central role in various chronic and acute inflammatory pathologies including diabetes only a few studies were carried out to analyze the relationship between the platelet indices and ...
6
The Relationship between Type 2 Diabetes and Platelet Indicators
... DM is a complex disease characterized by chron- ic hyperglycemia responsible for complications affecting the kidneys, eyes, peripheral nerves, and micro and macrovascular systems. The reported prevalence of diabetes in ...
6
Functional domains on von Willebrand factor Recognition of discrete tryptic fragments by monoclonal antibodies that inhibit interaction of von Willebrand factor with platelets and with collagen
... all platelet adherence to artery subendothelium and to purified vessel wall collagen type III, at relatively high wall shear ...ristocetin-induced platelet aggregation and the binding of FVIII-VWF to ...
10
www.ijcep.com /IJCEP911005 Case Report Glanzmann’s thrombasthenia: report of a case and review of the literature
... disease. Type I and Type II result from muta- tions of GPIIb or GPIIIa that cause lack of ...the platelet surface [5, ...the Type III, or variant form [5, ...
5
A clinical study of spectrum of low platelet count to establish etiology, diagnosis, complications and prognosis in newborns admitted in Al-Ameen medical college hospital NICU, Bijapur, Karnataka, India
... A detailed history inclusive of maternal history and obstetric history with suggestive of a bleeding and its type in the newborn or the mother was obtained as per the pro forma. Gestational age of all neonates was ...
7
LIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B
... to platelet formation in the blood stream of marrow sinusoids ...of platelet formation, as well as in the maturation and sizing of platelets to produce the homogeneous mature platelet population (6, ...
18
von Willebrand factor mutation enhancing interaction with platelets in patients with normal multimeric structure
... as type I New York or type Malmö is characterized by enhanced ristocetin-induced platelet agglutination with normal von Willebrand factor multimeric distribution in ...
10
Platelets of mice heterozygous for neurobeachin, a candidate gene for autism spectrum disorder, display protein changes related to aberrant protein kinase A activity
... mean platelet volume (MPV) and platelet count were determined on an automated cell counter (Cell-Dyn 1300 Abbott laboratories, Abbott Park, IL, ...USA). Platelet-rich plasma (PRP) was obtained after ...
13
Inhibition of angiogenesis by platelets in systemic sclerosis patients
... assess platelet-derived angiogenic and antiangiogenic factors, in vitro tubule formation assays were performed with human DMVECs [catalogue number CRL-4025; American Type Culture Collection (ATCC), ...
9
A common uptake system for serotonin and dopamine in human platelets
... Kinetic and pharmacologic properties of uptake of serotonin and dopamine by normal human platelets have been investigated to test whether platelets can be employed as a model system for the reuptake of serotonin and ...
7
Impaired Glucose Tolerance is Associated with
... Haemoglobin (g/dL) 25.85[20.00- 29.23] 22.40[16.75- 25.00] 0.6683 Haematocrit (%) 31.10[30.05- 33.30] 29.00[23.00- 31.40] 0.0433 Mean cell volume (fL) 43.00[43.00- 43.75] 42.00[41.00- 44.00] 0.0025 Platelet count ...
10
Immunochemical Evidence for Protein Abnormalities in Platelets from Patients with Glanzmann's Thrombasthenia and Bernard Soulier Syndrome
... I-labeled type I thrombasthenic platelets showed no periodic acid- Schiff bands or peaks of radioactivity in the GP IIb and GP IIIa regions, whereas in the GP I region both the periodic acid-Schiff band intensity ...
11
Evaluation of the relationship between platelet indices and lipid profile in obese adolescents with hepatosteatosis
... in platelet indices have a significant impact in thrombotic and pre- thrombotic ...evaluate platelet indices such as the platelet count (PLT), mean platelet volume (MPV) and platelet ...
5