pluripotency/stem cells
Dedifferentiation of human uterine polyp stem cells into embryo-like cells during inducing pluripotency
... somatic cells can be reprogrammed into embryonic stem cell capable of pluripotent ...polyp-mesenchymal stem cells (EPMSCs and CPMSC), we showed introduction of the four transcription factors ...
13
Signaling pathways dictating pluripotency in embryonic stem cells
... true stem cells in agriculture and how can we conquer it? The answer might lie in the fact that there is a basic difference in the development of embryo within different mammalian species (Nichols & ...
10
Computational inference of a genomic pluripotency signature in human and mouse stem cells
... embryonic stem cells (ESCs) from human and ...to pluripotency genes: i) an enrichment for known pluripotency regulators ...the pluripotency signature in mouse and human ESCs sug- gests ...
14
Pluripotency and differentiation in embryos and stem cells Pavia, 17 18 January 2008
... of pluripotency transcription factors in CSCs still remains as questionable as it has always been (Cantz et ...somatic stem cells hit by oncogenic insults or whether they are instead the product of ...
10
Original Article Human amniotic fluid stem cells support undifferentiated propagation and pluripotency of human embryonic stem cell without b-FGF in a density dependent manner
... embryonic stem cells (hESCs) are pluripotent cells which can give rise to almost all adult cell lin- ...mesenchymal stem cells (MSCs) not only synthesize soluble cytokines or factors ...
13
Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells
... pluripotent stem cells (such as mouse ESCs (mESCs) and iPSCs) is still un- ...on pluripotency, disruption of Gas5 expression impaired the efficiency of somatic reprogramming to ...
13
Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency
... in cells of the inner-cell mass of the mouse embryo, pluripotency can be maintained in the absence of NANOG, for instance in mouse embryonic stem cells (mESCs) in which both Nanog alleles have ...
10
Pluripotency of induced pluripotent stem cells
... possesses pluripotency similar to that of ES ...pluripotent stem cell via the ectopic expression of only four transcription fac- tors, namely Oct4, Sox2, Klf4 and ...pluripotent stem cells ...
7
Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease
... include pluripotency, self-renewal and similar gene expression ...stringent pluripotency assay, tetraploid embryo complementation, demonstrated that mouse iPSCs can give rise to all tissues of the embryo ...
13
Equine embryos and embryonic stem cells: defining reliable markers of pluripotency
... Pluripotency markers in equine embryos 217 218 Since early equine embryogenesis differs significantly to that of the mouse, pig, cow and 219 human [34,53], it is reasonable to anticipate[r] ...
26
Rediscovering pluripotency: from teratocarcinomas to embryonic stem cells
... ES cells is hindering their efficient expansion, and creates a selection pressure that may lead to the generation of variants harboring advantageous genetic changes which can overtake the culture (Amps et ...the ...
11
The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells
... genes in a poised state to enable rapid activation or sta- ble silencing upon differentiation [59, 60]. The Hox fam- ily members belong to a series of transcription factors which are expressed by bivalent genes, and they ...
10
The proteasome complex and the maintenance of pluripotency: sustain the fate by mopping up?
... embryonic stem cells (hESCs) was first described by Sato and colleagues [20], identifying about 900 genes including PSMB8/β5i among the top ...pluripotent stem cells need more proteasomal ...
9
Human endogenous retrovirus K (HML 2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells
... endogenous pluripotency genes OCT4 and NANOG and absence of the differentiation marker gene LMNA in pluripotent stem cells, ACTB specific amplicons served as internal controls ...the ...
6
An overview of mammalian pluripotency
... pluripotent stem cell type called mouse epiblast stem cells (mEpiSCs) can be derived from a broad range of post-implantation epiblast tissues and show features distinct from mESCs (Brons et ...primed ...
5
Hütz, Katharina Antonia (2013): The role of the transcription factor SOX2 in tumorigenesis and development of the stomach. Dissertation, LMU München: Medizinische Fakultät
... for pluripotency in ES cells (see Introduction ...to pluripotency in adult stem cells, evidences have accumulated that SOX2 plays an important role in these cells ...Sox2+ ...
194
The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer
... CRC cells in ...CRC cells by regulating Wnt/β-catenin signaling, which was supported by data showing that miR-371-373 expression was correlated with Wnt/β-catenin signaling activity in several human cancer ...
14
Targeted DamID reveals differential binding of mammalian pluripotency factors
... of cells, precluding the identification of transcription factor targets in small populations of cells, including stem cells in ...parental cells or cell lines expressing Dam alone ...of ...
11
Age-associated changes in the ecological niche: implications for mesenchymal stem cell aging
... embryonic-like stem cells (VSELs) within the BM are age depleted ...BM stem cell ...and pluripotency-associated markers is sug- gestive of prior contamination by VSELs during primary isolation ...
11
X chromosome inactivation in the cycle of life
... pluripotent stem (iPS) cells (Maherali et ...somatic cells with embryonic carcinoma (EC) cells (Takagi et ...iPS cells, nor expression of EC-specific pluripotency genes in hybrid ...
5