Pluronic F127
Enhancing the oral bioavailability of biochanin A by encapsulation in mixed micelles containing Pluronic F127 and Plasdone S630
... system. Pluronic F127 consists of polyoxyethylene (PEO) units (70%) and polyoxy- propylene (PPO) blocks (30%) and has a versatile triblock composition of ...microenvironment. F127 is widely used in ...
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ENHANCING SOLUBILITY AND DISSOLUTION OF IBUPROFEN BY SPRAY DRYING USING PLURONIC F127
... of F127 were produced by spray drying using dichloromethane as solvent to enhance solubility and dissolution ...and pluronic F127 were significant improved compared with its physical mixture and pure ...
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Pentablock copolymers of pluronic F127 and modified poly(2-dimethyl amino)ethyl methacrylate for internalization mechanism and gene transfection studies
... study, we tried to copolymerize pluronic F127 (PF127) with PDMAEMA to reduce the cytotoxicity of PDMAEMA as a gene vector. However, when we prepared pentablock copo- lymers of PF127-pDMAEMA with different ...
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Understanding paclitaxel _ pluronic F127 nanocrystals prepared by the stabilization of nanocrystal (SNC) method
... of Pluronic F127 preferred hydrophobic Carbon Black (CB) particle surface to water, but above CMC Pluronic F127 preferred to associate with each other and had decreased affinity to CB surface ...
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Redox-sensitive Pluronic F127-tocopherol micelles: synthesis, characterization, and cytotoxicity evaluation
... Abstract: Pluronic F127 (F127), an amphiphilic triblock copolymer, has been shown to have significant potential for drug delivery, as it is able to incorporate hydrophobic drugs and self- assemble ...
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Structure Change of Polyethersulfone Hollow Fiber Membrane Modified with Pluronic F127, Polyvinylpyrrolidone, and Tetronic 1307
... Hydrophilic polyethersulfone (PES) hollow fiber membranes were prepared via non-solvent induced phase separation (NIPS) by addition of polymeric additives as a membrane modifying agent. The effect of the addition of ...
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Synthesis and Charaterization of Magensium Oxide Mesoporous Microstructures Using Pluronic F127
... Mesoporous MgO microstructures were synthesized using magnesium acetate tetrahydrate, ammonium oxalate monohydrate and Pluronic F127 via heating at 40 °C for 24 h and subsequent calcination. The mesoporous ...
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<p>Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes Combined Pluronic F127 Hydrogel Promote Chronic Diabetic Wound Healing and Complete Skin Regeneration</p>
... Previous studies have shown that a variety of hydrogels could promote the healing of chronic wounds. For example, a Poly-N-acetyl glucosamine hydrogel (matrix system) derived from microalgae shows a potential therapeutic ...
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Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats
... the F127 plus methyl cellulose gel followed zero order kinetics and correlated linearly with the weight percentage of gel dissolved, demonstrating that the overall rate of release of PNS is controlled by ...
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Preparation, optimization, and in vitro simulated inhalation delivery of carvedilol nanoparticles loaded on a coarse carrier intended for pulmonary administration
... The PXRD patterns shown in Figure 7 indicated that CAR exhibited three sharp characteristic diffraction lines at 2 θ of 5.8 ° , 14.7 ° , and 24.5 ° and multiple short lines between 2 θ of 10 ° and 30 ° . Pluronic ...
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Ovulatory and Reproductive Characteristics of Sows Treated with an Intravaginal GNRH Agonist Gel
... The onset of heat after weaning, heat duration, and ovulation as major factors in artificial insemination timing in sows.. Pluronic F127 gel formulations of desorelin and GnRH reduce d[r] ...
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<p>Development of anti-HER2-targeted doxorubicin–core-shell chitosan nanoparticles for the treatment of human breast cancer</p>
... Chitosan (molecular weight cut-off (MWCO) <50,000; degree of deacetylation, 90%) was purchased from Seafresh Chitosan Laboratory (Bangkok, Thailand). Pluronic ® F127 (Poloxamer 407) was acquired from ...
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Functional Nanofibers and Colloidal Gels: Key Elements to Enhance Functionality.
... Figure E.1 Photographs and SEM photomicrographs of the top surface of electrospun (a-b) alginate/PEO/Pluronic F127 blended nanofibers, (c-d) alginate only nanofibers following [r] ...
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Formulation and In-Vitro Evaluation of Raloxifene Hydrochloride Loaded Mixed Pluronic L121/F127 Polymeric Micelles
... by pluronic triblock copolymer whose poly (ethylene oxide) block are sterically stabilized (stealth) and undergo less opsonization and uptake by the macrophages of the reticuloendothelial system ...using ...
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EFFECTS OF PORPHYRA VIETNAMENSIS EXTRACT ON TNBS INDUCED COLITIS IN RATS
... 20% pluronic F127 gel was prepared, and its gelation, gel melting temperatures as well as bio-adhesive strength were determined, (v) anti-inflammatory potential of PE against the intestinal inflammatory ...
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Pluronic based nano-delivery systems; Prospective warrior in war against cancer
... with pluronic based delivery systems? Firstly, unlike many other drug delivery systems which merely act as a simple carrier, pluronics are pharmacologically active polymers which can modulate the response of ...
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PREPARATION AND CHARACTERIZATION OF METFORMIN LOADED STEARIC ACID COUPLED F127 NANOPARTICLES
... [15]. Pluronic F127 10 g and SA 10 g were added in 100 ml round bottom flask and the mixture was heated with constant stirring to yield a well-mixed molten phase and reacted at 155°C for ...
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PubMedCentral-PMC5586074.pdf
... with Pluronic F127 (abbreviated as F127 hereafter) could reduce the adhesion of similarly sized and hydrophobic NS to ...mucus. F127 is a Generally Regarded As Safe (GRAS) by the FDA material ...
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AlPcS<sub>4</sub>-PDT for gastric cancer therapy using gold nanorod, cationic liposome, and Pluronic<sup>®</sup> F127 nanomicellar drug carriers
... and Pluronic F127 drug delivery vectors to increase the AlPcS 4 delivery efficiency, reduce the binding affinity of AlPcS 4 to serum proteins, and enhance SOG generation, which led to a highly efficient ...
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Improved delivery of PLGA microparticles and microparticle cell scaffolds in clinical needle gauges using modified viscosity formulations
... B PLGA microparticle delivery from a stock of 5mg/ml through syringes fitted with various needle gauges C, D, E Increasing concentrations of pluronic F127 C CMC D and pluronic F127/CMC c[r] ...
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