pneumococcal carriage
Inflammation induced by influenza virus impairs innate control of human pneumococcal carriage
... to pneumococcal carriage, we measured levels of 30 cytokines in nasal lining fluid (Fig ...Spn carriage in the absence of LAIV was associated with increased levels of EGF at day 2 (p = ...by ...
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Modulation of nasopharyngeal innate defenses by viral coinfection predisposes individuals to experimental pneumococcal carriage
... via Pneumococcal surface protein C (PspC), 19 facilitating adherence to epithelial ...step, pneumococcal uptake, is integrin mediated and depends on host signaling molecules such as phospha- tidylinositol ...
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Pneumococcal carriage in households in Karonga District, Malawi, before and after introduction of 13 valent pneumococcal conjugate vaccination
... on pneumococcal carriage prevalence after routine introduction of PCV13 in a vaccine-naive sub-Saharan country using a 3+0 ...VT carriage three years after PCV13 introduction in this rural Malawi ...
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Herd immunity alters the conditions for performing dose schedule comparisons: an individual based model of pneumococcal carriage
... details. Carriage prevalence by serotype was calibrated to data from Massachusetts, USA [31], and the details of carriage prevalence overall can vary considerably across populations, though the leading ...
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Influence of the pneumococcal conjugate vaccines on the temporal variation of pneumococcal carriage and the nasal microbiota in healthy infants: a longitudinal analysis of a case–control study
... invasive pneumococcal disease, colonization needs therefore to be prevented [2, ...PCVs, pneumococcal serotype replacement and a decrease of pneumococcal carriage has been described [42, ...
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Pneumococcal carriage among HIV infected children in Accra, Ghana
... Pneumococcal carriage is the precursor for development of pneumococcal disease, and is also responsible for transmission of the organism from person-to-person ...Recent pneumococcal vaccines ...
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Impact of viral upper respiratory tract infection on the concentration of nasopharyngeal pneumococcal carriage among Kenyan children
... nasopharyngeal pneumococcal density at the individual level as we did, and did not look at the mag- nitude of change relative to the variation within ...in pneumococcal density among virus-negative children ...
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Characterisation of Treg and Th17 cells in Nasopharynx-associated lymphoid tissue and their association with pneumococcal carriage in children and adults
... in pneumococcal culture- negative children than in ...of pneumococcal clearance or persistence/carriage in human ...following pneumococcal CCS ...that pneumococcal proteins including ...
238
Antibodies to Pneumococcal Proteins PhtD, CbpA, and LytC in Filipino Pregnant Women and Their Infants in Relation to Pneumococcal Carriage
... three pneumococcal vaccine candidate proteins in Filipino infants, all inducing protection in animal models: pneumococcal histidine triad protein D (PhtD), choline binding protein A (CbpA), and the lysozyme ...
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Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung
... Pneumococcal carriage is both immunising and a pre-requisite for mucosal and systemic ...of pneumococcal colonisation show that IL-17A-secreting CD4 + T-cells (Th-17 cells) are essential for ...
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Molecular Epidemiology of Pneumococcal Carriage among Children with Upper Respiratory Tract Infections in Hanoi, Vietnam
... investigated pneumococcal car- riage in healthy children in South Korea, we noticed slight differences in the serotype ...of carriage of serotype 23F was twice as high in the Vietnamese children with upper ...
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Pneumococcal carriage in households in Karonga District, Malawi, before and after introduction of 13 valent pneumococcal conjugate vaccination
... on pneumococcal carriage prevalence after routine introduction of PCV13 in a vaccine-naive sub-Saharan country using a 3 + 0 ...VT carriage three years after PCV13 introduction in this rural Malawi ...
8
Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage
... increased pneumococcal agglutination capacity compared to nasal wash samples collected before ...new carriage events but does not impact pre-existing ...natural carriage generates protective ...
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Emerging pneumococcal carriage serotypes in a high risk population receiving universal 7 valent pneumococcal conjugate vaccine and 23 valent polysaccharide vaccine since 2001
... Our survey of 1720 young children in remote communi- ties two and four years after commencement of a govern- ment funded schedule for Indigenous children of 7PCV at 2, 4 and 6 months followed by a booster 23PPV at 18 ...
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Impact of Experimental Human Pneumococcal Carriage on Nasopharyngeal Bacterial Densities in Healthy Adults
... of pneumococcal carriage, experimental studies in adults will likely be the best approximation we can achieve for observing pneumococcal colonization in a controlled ...Sa carriage 14 days ...
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Experimental human pneumococcal carriage
... for carriage by qPCR was significantly more than the proportion of samples positive for carriage by ...of pneumococcal carriage by culture is the gold standard ...
216
Maternal Antibodies to Pneumolysin but Not to Pneumococcal Surface Protein A Delay Early Pneumococcal Carriage in High-Risk Papua New Guinean Infants
... and pneumococcal surface protein A (PspA) are two conserved proteins that are expressed by vir- tually all ...facilitating carriage and disease ...between pneumococcal strains and has been classified ...
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The immunological mechanisms that control pneumococcal carriage
... Three pneumococcal vaccine formulations are currently licensed, all of which induce humoral responses against a subset of the 98 currently described immunologically distinct capsular polysaccharide serotypes [22, ...
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Dynamic models of pneumococcal carriage and the impact of the Heptavalent Pneumococcal Conjugate Vaccine on invasive pneumococcal disease
... on carriage of vac- cine- and non-vaccine pneumococcal serotypes (VT and NVT) and on invasive pneumococcal disease ...of pneumococcal carriage and disease are highly correlated with ...
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Revisiting Pneumococcal Carriage by Use of Broth Enrichment and PCR Techniques for Enhanced Detection of Carriage and Serotypes
... and carriage serotypes are still poorly ...of pneumococcal strains to progress from NP car- riage to invasive disease are still subjective, at least to some ...current carriage methods are not ...
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