Poliovirus infection
Down regulation of poliovirus receptor RNA in HeLa cells resistant to poliovirus infection.
... Treatment of SOFIA cells with 5-azacytidine 5-azaC, a potent demethylating agent, resulted in partial restoration of susceptibility to * poliovirus infection, accompanied by increased le[r] ...
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Enhanced intracellular calcium concentration during poliovirus infection.
... in poliovirus-infected HeLa ...during poliovirus infection. Poliovirus infection was performed, as described above, at an MOI of 50 on cells growing in 35-mm- diameter culture ...and ...
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Cellular origin and ultrastructure of membranes induced during poliovirus infection.
... other poliovirus-induced ...of poliovirus- induced membranes, and there is no reason to suspect that a subset of these membranes does not contain functional RNA replication ...in poliovirus ...
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Poliovirus Infection Transiently Increases COPII Vesicle Budding
... Changes in Sec31A labeling of ERES parallel observed changes in COPII budding. The increase in COPII vesicle forma- tion we observed early in PV infection could be due to a change in ERES, either quantitatively or ...
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Valosin-Containing Protein (VCP/p97) Is Required for Poliovirus Replication and Is Involved in Cellular Protein Secretion Pathway in Poliovirus Infection
... VCP acts as a host factor of PV replication via a cellular se- cretion pathway. Next, we attempted to isolate a resistant PV mutant that could show efficient infection in VCP-knockdown cells. We repeated passage ...
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Modification of RNA polymerase IIO subspecies after poliovirus infection.
... After SDS-PAGE, the proteins were transferred to nitrocellulose filters as described by Towbin et RESULTS Characterization of RNA polymerase II subspecies in HeLa cell lysates at differe[r] ...
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Poliovirus infection results in structural alteration of a microtubule-associated protein.
... In an attempt to elucidate the changes in cellular proteins involved in the shutoff of host protein synthesis, monoclonal antibodies were prepared by immunizing mice with a partially pur[r] ...
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Persistent poliovirus infection of human fetal brain cells.
... that poliovirus (PV), the causative agent of poliomyelitis, could persist in surviving ...after infection, viral antigens were found in cells of both the neuronal and glial ...after infection, viral ...
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Persistent poliovirus infection in mouse motoneurons.
... PV infection in the spinal cord, as suggested by the presence of anti-PV immunoglobulin M (IgM) antibodies (32) and fragmentary genetic sequences resembling PV RNA (21, 22, 25) in spinal fluid from postpolio ...
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Poliovirus Infection and Poly(A) Sequences of Cytoplasmic Cellular RNA
... The present work examines whether infection of HeLa S3 cells with poliovirus leads to a more rapid degradation of PolyA sequences which in turn might explain the observed effect on cellu[r] ...
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Community Acquired Poliovirus Infection in Children with Primary Immunodeficiencies in Tunisia
... recent infection, most likely during ...vaccine-derived poliovirus strain can be esti- mated by determining the extent of its divergence from the original Sabin strain, the rate of nucleotide changes per ...
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Poliovirus-Induced Apoptosis Is Reduced in Cells Expressing a Mutant CD155 Selected during Persistent Poliovirus Infection in Neuroblastoma Cells
... PV infection may promote an early apoptotic reaction whereas, upon productive PV infection, ap- optosis appeared to be blocked by a distinct antiapoptotic function of PV (1, 2, 42, ...PV infection in ...
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Interactions between Viral and Prokaryotic Pathogens in a Mixed Infection with Cardiovirus and Mycoplasma
... hand, the failure of Q-VD (which appeared to be essentially devoid of detectable side effects in the systems studied) to prevent this degradation FIG. 4. Effect of caspase inhibitors on DNA degradation in EMCV-infected ...
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Inhibition of host cell transcription by poliovirus: cleavage of transcription factor CREB by poliovirus-encoded protease 3Cpro.
... whether poliovirus infection results in the inactivation of CREB transcriptional activity, CREB was purified by DNA affinity chromatography from mock- and vi- rus-infected cell ...from poliovirus-in- ...
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Inhibition of basal transcription by poliovirus: a virus- encoded protease (3Cpro) inhibits formation of TBP-TATA box complex in vitro.
... Poliovirus infection inhibits basal ...that infection of HeLa cells with poliovirus resulted in drastic inhibition of TATA- mediated USF-activated transcription from the Ad MLP (10, ...by ...
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Cleavage of Poly(A)-Binding Protein by Enterovirus Proteases Concurrent with Inhibition of Translation In Vitro
... Enteroviruses are members of the family Picornaviridae and are the etiologic agents responsible for many pathological syn- dromes. Since nearly all enteroviruses cause drastic inhibition of host cell translation (17, 25, ...
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Inhibition of poliovirus RNA synthesis by brefeldin A.
... During poliovirus infection in the absence of the RNA replication inhibitor, both the accumulation of labeled poliovirus proteins and the inhibition of host cell protein synthesis 17, 39[r] ...
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Cellular mRNA Decay Protein AUF1 Negatively Regulates Enterovirus and Human Rhinovirus Infections
... in poliovirus-infected cells; the functional consequences of this degradation are unknown, but they may aid in the disruption of processing bodies (complexes of stalled mRNAs) seen during poliovirus ...
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Poliovirus Proteins Induce Membrane Association of GTPase ADP-Ribosylation Factor
... report poliovirus-specific activation of an- other class of cellular proteins that is likely to be important for viral RNA ...of poliovirus genomic RNA or RNAs encoding either of two individual ...
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Inhibition of Nuclear Import and Alteration of Nuclear Pore Complex Composition by Rhinovirus
... during poliovirus infection, Nup153 and p62 were degraded, correlating with the relocalization of cel- lular proteins and the inability of infected cells to mediate import in vitro ...rhinovirus ...
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