poly adenosine
Synthesis of DNA and Poly(Adenosine Diphosphate Ribose) in Normal and Chronic Lymphocytic Leukemia Lymphocytes
... and poly-(adenosine diphosphate ribose) (poly[ADPR]) immediately after isolation and on successive days following their treatment with phytohemagglutinin ...
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Association of Poly(Adenosine Diphosphoribose) Synthesis with DNA Damage and Repair in Normal Human Lymphocytes
... poly(adenosine diphosphoribose) synthesis was dependent upon the UV dose. Alkaline CsCl gradient studies, with bromodeoxyuridine triphosphate density labeling of DNA, demonstrated that the unscheduled DNA ...
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Novel treatment strategies in triple-negative breast cancer: specific role of poly(adenosine diphosphate-ribose) polymerase inhibition
... the poly(adenosine triphosphate-ribose) polymerase (PARP)-1 enzyme induce synthetic lethality in cancers with ineffective DNA (DNA) repair or homologous repair deficiency, and have shown promising clinical ...
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Titrating Gene Function in the Human Fungal Pathogen Candida albicans through Poly-Adenosine Tract Insertion
... of poly-adenosine (poly-A) tracts into an open reading frame can suppress expression of the encoded protein in both prokaryotic and eukaryotic ...the poly-A insertion, which can therefore ...
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Inhibition of poly (adenosine diphosphate-ribose) polymerase attenuates lung-kidney crosstalk induced by intratracheal lipopolysaccharide instillation in rats
... enzyme poly (adenosine diphosphate-ribose) poly- merase (PARP) catalyzes the attachment of ADP ribose units to target proteins and plays an important role in modulating both chromatin structure and ...
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Human autoantibodies to poly(adenosine diphosphate ribose) polymerase
... Acetone-fixed HEp-2 cells Bion Enterprises, Ltd., Park Ridge, IL were reacted with either a serum containing antibodies to ADPRP or affinity purified anti-ADPRP IgG, and followed by fluo[r] ...
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Human autoantibodies to poly(adenosine diphosphate ribose) polymerase recognize cross reactive epitopes associated with the catalytic site of the enzyme
... The factors responsible for the production of autoantibodies against self-components are not well understood. We have identified monospecific human autoantibodies to poly(ADP- ribose) polymerase (ADPRP) in the ...
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Delivering widespread BRCA testing and PARP inhibition to patients with ovarian cancer.
... Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serous ovarian cancer and a BRCA mutation: Overall survival adjusted for postprogression poly(adenosine diph[r] ...
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Clinical factors of response in patients with advanced ovarian cancer participating in early phase clinical trials.
... as poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors, where early studies of olaparib showed response rates of 69% in those with platinum-sensitive disease, compared with 45% and 23% in the ...
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Effect of nanostructured TiO<sub>2</sub> crystal phase on photoinduced apoptosis of breast cancer epithelial cells
... Exposure of MDA-MB-468 cells to pure anatase nanoparticles or anatase–rutile mixtures for 48 hours resulted in increased proapoptotic Bax expression, caspase-mediated poly(adenosine[r] ...
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“NANOGEL AS A CONTROLLED DRUG DELIVERY SYSTEM” by Hitesh A. Patel*, Ravi R. Patel, Dr. Jayvadan K. Patel, India.
... on poly (vinyl alcohol), poly (ethylene oxide), poly (ethyleneimine), poly (vinyl pyrrolidone), and poly-N-isopropylacrylamide have been reported with different characteristics and ...
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Adenosine and lidocaine (AL) combination dilates intimally damaged rat thoracic aortic rings and guinea pig mesenteric arteries: possible significance to cardiac surgery
... of adenosine and lido- caine, but was dominated by adenosine and a complex dilation-contraction behavior from lidocaine (Figures 2 and ...both adenosine and lidocaine on both cell types (see ...
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The effects of adenosine and adenosine monophosphate on calcium induced mitochondrial swelling
... of adenosine and adenosine monophosphate on calcium induced mitochondrial ...calcium, adenosine and adenosine monophosphate on isolated normal male rat liver mitochondria were studied and also ...
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Adiponectin hormone, adenosine deaminase enzyme and insulin adiponectin hormone, adenosine deaminase enzyme and insulin hormone levels in type 2 diabetic iraqi patients
... mostly by adipocytes and is important regulator of lipid and glucose metabolism. It is established that adiponect in is an insulin-sensitizing hormone with anti-diabetic, anti- inflammatory and anti- atherogenic ...
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Sedative effects of peanut (Arachis hypogaea L ) leaf aqueous extracts on brain ATP, AMP, Adenosine and Glutamate/GABA of rats
... brain adenosine triphos- phate (ATP) (p < ...brain Adenosine monophosphate (AMP) were clearly de- creased (p < ...brain Adenosine revealed an in- creasing propensity (p = ...
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Leishmaniasis and glycosaminoglycans: a future therapeutic strategy?
... Abbreviations ADP: adenosine diphosphate; AMP: adenosine monophosphate; ATP: adenosine triphosphate; bFGF: basic fibroblast growth factor; CD: cluster of differentiation; CHO cells: Chin[r] ...
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Sequence-based prediction of permissive stretches for internal protein tagging and knockdown
... ADP: Adenosine diphosphate; AMP: Adenosine monophosphate; ASA: Absolute surface area; aTc: Anhydrotetracycline; ATP: Adenosine triphosphate; Bla: β -lactamase; CFX: Cell-free extract; CoS- MAGE: ...
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Anoxic metabolism and biochemical production in Pseudomonas putida F1 driven by a bioelectrochemical system
... ADP: adenosine diphosphate; AEC: adenylate energy charge; AMP: adenosine monophosphate; ATP: adenosine triphosphate; BES: bioelectrochemical sys- tem; CB: carbon balance; CDW: cell dry [r] ...
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Evaluating the effects of crystallinity in new biocompatible polyester nanocarriers on drug release behavior
... Abstract: Four new polyesters based on 1,3-propanediol and different aliphatic dicarboxylic acids were used to prepare ropinirole HCl-loaded nanoparticles. The novelty of this study lies in the use of polyesters with ...
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Oxidative stress impairs energy metabolism in primary cells and synovial tissue of patients with rheumatoid arthritis
... as adenosine triphosphate synthase subunit β (ATP5B), suc- cinate dehydrogenase flavoprotein subunit and reduced form of nicotinamide adenine dinucleotide (NADH) de- hydrogenase iron–sulphur protein 2 in the ...
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