poly (D,L-lactide) nanoparticles
Antitumoral activity of L-ascorbic acid-poly-D,L-(lactide-co-glycolide) nanoparticles containing violacein
... of poly- D,L-(lactide-co-glycolide) 50:50 loading the antitumoral compound violacein and capped with L-ascorbic ...acid. Nanoparticles were prepared using the nanoprecipitation ...
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Controlled-release of tetracycline and lovastatin by poly(D,L-lactide-co-glycolide acid)-chitosan nanoparticles enhances periodontal regeneration in dogs
... PLGA-lovastatin-chitosan-tetracycline nanoparticles, which allows the sequential release of tetracycline and lovastatin to effectively control local infection and promote bone regeneration in ...of ...
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Biodegradable nanoparticles of methoxy poly(ethylene glycol) b poly( d, l lactide)/methoxy poly(ethylene glycol) b poly(ϵ caprolactone) blends for drug delivery
... methoxy poly(ethylene glycol)-b-poly(D,L-lactide) (MPEG-b-PDLL)/methoxy poly(ethylene glycol)-b-poly( E -caprolactone) (MPEG-b-PCL) blends on nanoparticle characteristics ...
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Development of novel cationic chitosan- and anionic alginate–coated poly(D,L-lactide-<em>co</em>-glycolide) nanoparticles for controlled release and light protection of resveratrol
... (Alg)-coated poly( d , l -lactide-co-glycolide) nanoparticles (NPs) loaded with the bioactive polyphenolic trans-(E)-resveratrol (RSV) for biomedical ...
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Distribution of β-carotene-encapsulated polysorbate 80-coated poly(D, L-lactide-co-glycolide) nanoparticles in rodent tissues following intravenous administration
... Biodegradable nanoparticles (NPs) composed of poly(D, L-lactide-co-glycolide) (PLGA) have attracted considerable attention as delivery systems of drugs and antioxidative compounds, such ...
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Effect of Nigella Sativa Encapsulated in Poly (Lactide-Co-Glycolide) Nanoparticles on Plasma Malondialdehyde and Ischemia-Modified Albumin in A Diabetes Rat Model
... biodegradable nanoparticles delivery system [e.g.,poly (lactide-co-glycolide)(PLGA)] offers enhancing in antioxidant ...PLGA nanoparticles on plasma MDA and IMA levels in type 2 DM model ...
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Preparation, characterization, and in vitro and in vivo investigation of chitosan-coated poly (d,l-lactide-co-glycolide) nanoparticles for intestinal delivery of exendin-4
... µ L distilled ...MICCRA D-1 homogenizer (ART Prozess- & Labortechnik GmBH & Co KG, Müllheim, Germany) at 20,000 rpm for 180 ...3% poly- vinyl alcohol (PVA) and sonicated for 60 seconds to ...
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Emulgel: A Boon for Dermatological Diseases
... One such research was carried by M.Vettor et al who studied the uv filter distribution and release in skin layer of octyl-methoxycinnamate loaded poly(D,L-lactide) nanoparticles [r] ...
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Investigation of endocytosis and cytotoxicity of poly-<em>d</em>, <em>l</em>-lactide-poly(ethylene glycol) micro/nano-particles in osteoblast cells
... acids. Poly-d,l-lactide-poly(ethylene glycol) (PELA) copolymers with different weight ratios of polyethylene glycol (PEG) were used as drug car- riers in the present ...of ...
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Glycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake
... here poly- lactide-co-glycolide (PLGA) NPs in the range of 100–150 nm bearing various proteoglycans were synthesized by a single-step nanoprecipitation and ...
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Interaction of Immune System Protein with PEGylated and Un PEGylated Polymeric Nanoparticles
... Unmodified poly (D, L-lactide-co-glycolide) (PLGA-COOH) and modified (PLGA-PEG-NH2) NPs were prepared in ...PLGA-COOH nanoparticles were further purified using Amicon Ultra-4 ...
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Toll-like receptor 3-induced immune response by poly(D,L-lactide-co-glycolide) nanoparticles for dendritic cell-based cancer immunotherapy
... + poly I:C)- ...+ poly I:C)-NPs showed significantly higher inhibition of tumor growth compared to DCs alone (control group, 93% reduction; ...and D). Notably, 100% of mice vaccinated with PLGA (OVA ...
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PLGA: A POLYMER OF CHOICE AS NANOCARRIER’S TO ACHIEVE EFFECTIVE DELIVERY OF MEDICINAL SUBSTANCES
... Poly (D,L-lactide-co-glycolic acid) the first synthetic biodegradable polymer used in surgery as resorbabe material, is also approved by USFDA for use in drug delivery. The nanoparticle ...
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<em>Chlamydia trachomatis</em> recombinant MOMP encapsulated in PLGA nanoparticles triggers primarily T helper 1 cellular and antibody immune responses in mice: a desirable candidate nanovaccine
... and D) using a multiplex enzyme- linked immunosorbent ...PLGA, poly D, L-lactide-co-glycolide; PBS, phosphate-buffered saline; rMOMP, recombinant major outer membrane protein; GM-CSF, ...
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Conjugation Magnetic PAEEP PLLA Nanoparticles with Lactoferrin as a Specific Targeting MRI Contrast Agent for Detection of Brain Glioma in Rats
... amphiphilic poly(aminoethyl ethylene phosphate)/poly(L-lactide) (PAEEP-PLLA) copolymer ...PAEEP-PLLA nanoparticles (M-PAEEP-PLLA-NPs) were further conjugated with lactoferrin (Lf) for ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... The nanoparticles were purified by applying two cycles of centrifugation (12,000 rpm for 1 hour in a Biofuge 28 RS, Heraeus centrifuge) and reconstituted with deionized and distilled ...the nanoparticles, ...
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“Pharmacokinetic Study of Dry Powder Inhaler Formulations of Antiasthmatic Drugs” by Dhara P. Jain, Parag Vijay Jain, M. R. Bhalekar, India.
... Salbutamol Sulphate (RLCC, Mumbai), Budesonide (Glenmark Pharmaceuticals, Mumbai), 75:25 Poly (DL- lactide/glycolide copolymer) (PLGA) of IV 0.2dl/g (Purasorb PDLG 7502 received gift sample from Purac ...
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Fabrication of Biodegradable Polymeric Microspheres with Controllable Porous Structure for Cell Delivery
... Poly(D,L-lactide-co-glycolide) (PLGA, 75:25, Mw~106000) was purchased from Birmingham Polymers (Pelham, AL, USA). Gelatin (type A, from porcine skin), PVA (Mw13 000–23 000, 98% hydrolyzed), ...
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Improvement in Crystallizability and Melt Flow Property of Linear Poly(L-lactide) Bioplastic by Blending with Star-shaped Poly(L-lactide)
... This research focuses on the crystallizability and melt flow property of linear poly(L-lactide) (1-PLL) by blending with star-shaped 16-arm PLL (16-PLL). The 1-PLL/16-PLL blends were chain extended ...
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Increased survival rate by local release of diclofenac in a murine model of recurrent oral carcinoma
... Abstract: Despite aggressive treatment with radiation and combination chemotherapy following tumor resection, the 5-year survival rate for patients with head and neck cancer is at best only 50%. In this study, we ...
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