Polyclonal activation
Effect of Contaminating Red Blood Cells on OKT3-Mediated Polyclonal Activation of Peripheral Blood Mononuclear Cells
... Cytokine production increased with the addition of RBC to the OKT3 activation cultures. The underlying reason for the enhancement in PBMC cytokine production when RBC were added to the OKT3 activation ...
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Anomalous antibody responses in viral infection: specific stimulation or polyclonal activation?
... In doubling dilution tests, a fourfold or greater increase in antibody titer between acute-phase A and convalescentphase C serum samples is considered to be a significant change in antib[r] ...
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Retrovirus-induced target cell activation in the early phases of infection: the mouse mammary tumor virus model.
... T-cell activation becomes detectable 2 to 3 days after ...a polyclonal activation which does not involve massive ...B-cell activation is T cell indepen- ...of activation, when only a ...
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Role of antigen selectivity in autoimmune responses to the Ku (p70/p80) antigen
... that polyclonal activation frequently, although not invariably, accompanies autoantibody ...that polyclonal activation might be secondary to autoantibody ...
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Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation
... In contrast, intracellular staining for cytokines after polyclonal activation with PMA/ionomycin revealed that individual CD4+ T cells obtained from BALF of OVA-DC/OVA mice produced eith[r] ...
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Polyclonal B cell activation in lupus prone mice precedes and predicts the development of autoimmune disease
... For example, while all NZB mice and no NZB mice developed polyclonal activation by 10 wk, 90% of F1 animals which are heterozygous at all loci and just over half of backcross mice which [r] ...
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Human immunodeficiency virus infection induces both polyclonal and virus specific B cell activation
... of polyclonal activation but not with anti-HIV ...cell activation accompany (and may be predictive of) disease progression in HIV-infected ...
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Influenza Virus-Induced Type I Interferon Leads to Polyclonal B-Cell Activation but Does Not Break Down B-Cell Tolerance
... B-cell activation on its own is thought to be able to induce ...produce polyclonal antibodies and autoanti- bodies ...B-cell activation during infections are nu- merous; they include direct ...
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Replication of an acutely lethal simian immunodeficiency virus activates and induces proliferation of lymphocytes.
... Although direct polyclonal activation of normal B cells by multiple HIV-1 isolates has been reported 27, 32, this is unlikely to have occurred in the assays used in this study because i [r] ...
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A cytotoxic nonstructural protein, NS1, of human parvovirus B19 induces activation of interleukin-6 gene expression.
... and polyclonal activation of B cells in rheumatoid arthritis and indicates that NS1 protein may play a significant role in the pathogenesis of some B19-associated diseases by modulating the expression of ...
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Activation of human B cells by phosphorothioate oligodeoxynucleotides
... To investigate the potential of DNA to elicit immune responses in man, we examined the capacity of a variety of oligodeoxynucleotides (ODNs) to stimulate highly purified T cell- depleted human peripheral blood B cells. ...
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Urokinase receptor is a multifunctional protein: influence of receptor occupancy on macrophage gene expression
... Four independent approaches were used to achieve this: a polyclonal and monoclonal antibodies to uPAR directed to the ligand-binding domain of the molecule; b polyclonal antibodies to uP[r] ...
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CLINICAL APPLICATIONS Gel Electrophoresis pdf
... Polyclonal light chains appear as clustered nondis- crete spots following 2D-PAGE, and form cloudy zones with unevenly distributed densities. In about two-thirds of patients with MG, monoclonal light chains are ...
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Development of polyclonal antiserum against movement protein from Potato leafroll virus and its application for the virus detection
... or polyclonal) is the basis for the serology ...stage. Polyclonal and monoclonal MP antibodies specific to Barley yellow dwarf virus (Xie et ...2015), polyclonal MP antibody specific to Citrus ...
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Immunohistochemical detection of wheat protein in model samples
... microtome. Concerning the samples processed in paraffin blocks, polyclonal antibodies diluted 1:1500 achieved positive results only in the samples with up to 0.5% wheat protein additive. This was caused probably ...
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Comparative evaluation of polyclonal antibodies in
... Keywords : Irukandji syndrome, box jellyfish, CSL antivenom, nematocyst extracts, antigenicity; 49.. human sera, human antibodies2[r] ...
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Polyclonal light chains in cerebrovascular disease
... urinary polyclonal light chains may be a negative prognostic sign and represent the boundary between a revers- ible stage of renal dysfunction, namely nephrotic syndrome, in which there is still an opportunity for ...
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Malaria, a difficult diagnosis in a febrile patient with sub microscopic parasitaemia and polyclonal lymphocyte activation outside the endemic region, in Brazil
... Although polymerase chain reaction (PCR) can detect parasites down to a density of 0.01 parasites per microlitre and would, therefore, be very useful in sub-microscopic parasitaemia malaria, it is not usually available ...
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Evidence from the anti-idiotypic network that the acetylcholine receptor is a rabies virus receptor.
... A Lanes: 1, immunoprecipitation with polyclonal rabies virus CVS strain antibody showing multiple viral proteins; 2, immunoprecipitation with polyclonal rabies virus antibody and control[r] ...
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Epitope mapping of neutralizing monoclonal antibodies against duck hepatitis B virus.
... Studies with a polyclonal rabbit serum against duck hepatitis B surface antigen DHBsAg demonstrated reduced infectivity of DHBV, whereas virus infectivity was not affected by polyclonal [r] ...
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