Polymyxin B
Cation Concentration Variability of Four Distinct Mueller Hinton Agar Brands Influences Polymyxin B Susceptibility Results
... the polymyxin B susceptibility phenotype varied according to the MHA brand tested, probably due to the two-component regulatory system ...than polymyxin (13, ...
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Imprinted contact lenses for sustained release of polymyxin B and related antimicrobial peptides
... hydrogel B, led to smaller inhibition diameters, as expected from its slower release of the ...for polymyxin B sufficient to provide drug levels well above the minimum inhibitory concentration (MIC) ...
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Impact of hemoperfusion with polymyxin B added to hemofiltration in patients with endotoxic shock: a case–control study
... Methods: This prospective case–control study in the medical–surgical intensive care unit of a university hospital included consecutive adults patients with septic shock and suspected gram-negative bacteria infection with ...
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Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis
... respectively. Polymyxin B was used at a final concentration of 30 and 60 μ g/mL in cultures and similar levels of reduction in cytokine production were observed (data not ...with Polymyxin B ...
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Polymyxin B-induced skin hyperpigmentation: a rare case report and literature review
... ADR: Adverse drug reaction; AKI: Acute kidney failure; CPR: Cardiopulmonary resuscitation; CT: Computed tomography; DiSH: Drug-induced skin hyperpigmentation; EICU: Emergency intensive care unit; GIB: Gastrointestinal ...
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Effectiveness of polymyxin B immobilized fiber column in sepsis: a systematic review
... The search strategy and data abstraction were defined by a prospective protocol. We searched PubMed, and the Cochrane Collaboration Database through April 2006, using the following search terms: 'hemoperfusion or ...
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Irreproducible and Uninterpretable Polymyxin B MICs for Enterobacter cloacae and Enterobacter aerogenes
... to polymyxin resistance have been observed in other genera of bac- ...of polymyxin-resistant ...of polymyxin-resistant ...with polymyxin resistance for ...affecting polymyxin ...
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Polymyxin-B hemoperfusion in septic patients: analysis of a multicenter registry
... Background: In 2010, the EUPHAS 2 collaborative group created a registry with the purpose of recording data from critically ill patients suffering from severe sepsis and septic shock treated with ...
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Comparison of nephrotoxicity of Colistin with Polymyxin B administered in currently recommended doses: a prospective study
... or Polymyxin B. Second, even after starting Polymyxin B or Colistin, nephrotoxicity criteria were required to be ful- filled for at least 2 consecutive determinations 24 h apart, 48 h after ...
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Evaluation of the Rapid Polymyxin NP Test for Polymyxin B Resistance Detection Using Enterobacter cloacae and Enterobacter aerogenes Isolates
... Rapid polymyxin NP tests were interpreted according to the original protocol: a color change from orange to yellow in the well containing the isolate suspension with polymyxin B indicated a positive ...
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Development and validation method for simultaneous quantification of neomycin and polymyxin B by HPLC-ELSD and comparison with microbiological method
... and trichloroacetate acid (40 mM, pH 1.70–1.80) in gradient mode, flow rate at 1.0 ml/minute, detector gain of 6, and analysis time of 35 minutes. The linearity was achieved with a concentration of 100–500 µg/ml (r = ...
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A Case of Polymyxin b-Immobilized Fiber Column Treatment for Rapidly Progressive Interstitial Pneumonia Associated with Clinically Amyopathic Dermatomyositis
... the polymyxin b-immobilized fiber column itself traps activated blood neutrophils and monocytes, which may be involved in the reduction of releasing mediators [31– ...
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The effect of polymyxin B hemoperfusion on modulation of human leukocyte antigen DR in severe sepsis patients
... of Polymyxin B Hemoperfusion in a Randomized controlled trial of Adults Treated for Endo- toxemia and Septic shock (EUPHRATES), which finished in 2017 but is as yet ...
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In Vitro Evaluation of Antibiotic Synergy for Polymyxin B Resistant Carbapenemase Producing Klebsiella pneumoniae
... myxin B combination reduced both polymyxin B and tigecy- cline MICs, suggesting that tigecycline along with polymyxin B may be an effective option for ...
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In-vitro activity of polymyxin B in combination with imipenem, rifampicin and azithromycin versus multidrug resistant strains of Acinetobacter baumannii producing OXA-23 carbapenemases
... This definition is generally considered too relaxed [10], and if the more stringent definition (FICI ≤ 0.5) is applied only three of the double and two of the triple combina- tions would be considered synergistic, ...
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Rational use of intravenous polymyxin B and colistin: A review
... general, polymyxin B has better pharmacokinetics profiles because of its IV formulation as an active ...However polymyxin B concentration in urine is very minimal due to its non-renal ...
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Polymyxin B Alleviates Angiotensin II Induced Stress Fiber Formation and Cellular Hypertrophy
... Polymyxin B is widely used antibiotic in the clinic for resistant Gram-negative ...tion, polymyxin B-immobilized hemoperfusion cartridge has been used for endotoxin removal therapy in patients ...
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Efficacy of intravenous plus intrathecal/intracerebral ventricle injection of polymyxin B for post-neurosurgical intracranial infections due to MDR/XDR Acinectobacter baumannii: a retrospective cohort study
... or polymyxin B be administered intravenously and intraventricularly for the treatment of intracranial infections caused by carbapenem-resistant Acinetobacter species [11], but the quality of evidence is ...
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Polymyxin B hemoperfusion: a mechanistic perspective
... of polymyxin B. Mo- lecular studies on polymyxin B and LPS interaction have determined that a stable bond is created, with hydropho- bic interactions dominating the interaction for intermo- ...
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Effectiveness and safety of polymyxin B for the treatment of infections caused by extensively drug-resistant Gram-negative bacteria in Thailand
... on polymyxin B ...producing polymyxin B for therapy of XDR Gram-negative bacterial infections in Thai ...if polymyxin B should also be available in addi- tion to ...
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