poor prognosis
Original Article Decreased expression of histone deacetylase 10 predicts poor prognosis of gastric cancer patients
... In our study, HDAC10, a member of class II, is deceased in gastric cancer tissue compared with adjacent tissue by immunohistochemistry. HDAC10 expression was found to be signifi- cantly reduced in patients with large ...
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Early experience with chemotherapy intensification for poor prognosis metastatic germ cell cancer and unfavorable tumor marker decline
... with poor prognosis GCC were identified: 4 had liver metastases, 1 had brain metastases, 2 had bone metastases, and 1 had a small bowel metastasis (Table ...
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DESNT : a poor prognosis category of human prostate cancer
... exhibited poor outcome relative to other patients (p = ...novel poor prognosis category of human prostate cancer and will assist in the targeting of therapy, helping avoid treatment-associated ...
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Ezrin overexpression predicts the poor prognosis of gastric adenocarcinoma
... Results: Ezrin protein located in the cytoplasm and/or membrane in the migrating gastric cancer cells, and it mainly concentrated at the protrusion site; however, only cytoplasmic distribution was observed in the ...
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SIRT1 expression is associated with poor prognosis of lung adenocarcinoma
... Abstract: Several studies have reported that the overexpression of Sirtuin 1 (SIRT1) was associated with poor prognosis in various human cancers. However, little is known regarding the prognostic value of ...
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Upregulation of KIF20A correlates with poor prognosis in gastric cancer
... Therefore, we first explored the expression level of KIF20A in 37 GC patients and found that KIF20A expres- sion is generally upregulated at both transcriptional and translational levels compared to its corresponding ...
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DESNT: A Poor Prognosis Category of Human Prostate Cancer.
... basal, ERBB2-overexpressing and luminal cancer categories[10]. This mathematical approach has not proven successful when applied to prostate cancer microarray datasets[9,11]. However in our study the use of LPD, an ...
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CD73 is associated with poor prognosis in HNSCC
... Our results revealed that CD73 is significantly associated with a poor prognosis in HNSCC. Both gene expression and protein expression analyses confirmed the prognostic significance of CD73 in HNSCC, thus ...
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High CEP55 expression is associated with poor prognosis in non-small-cell lung cancer
... All patients participated for the duration of this study. About 102 (50.24%) patients were deceased, and 101 patients were still alive at the end of the duration of this study. The 5-year OS rates of the whole cohort ...
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Weak HIF 1alpha expression indicates poor prognosis in resectable pancreatic ductal adenocarcinoma
... with prognosis and absence of correlation between HIF-1alpha and CAIX suggests that the prognostic association of HIF-1alpha may not directly be linked with ...
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Elevated expression of Tiam1 is associated with poor prognosis and promotes tumor progression in pancreatic cancer
... Results: The results indicated that Tiam1 expression was significantly higher in PDAC tissues than in paired non-tumor tissues, and overexpression of Tiam1 was significantly correlated with histological grade (P=0.040) ...
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A high LDL-C to HDL-C ratio predicts poor prognosis for initially metastatic colorectal cancer patients with elevations in LDL-C
... The authors thank the patients and the colleagues at the Sun Yat-sen University Cancer Center who participated in this study. The abstract of this paper was presented at the 2014 World Congress as an oral presentation ...
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CMTM1 v17 is associated with chemotherapy resistance and poor prognosis in non small cell lung cancer
... Results: CMTM1_v17 expression was related to treatment effect and outcome in tumor tissues after NAC not before NAC from 31 cases of NSCLC. We identified that high CMTM1_v17 expression was associated with low objective ...
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Insight into the Role and Regulation of Gap Junction Genes in Lung Cancer and Identification of Nuclear Cx43 as a Putative Biomarker of Poor Prognosis
... Increased expression of connexin 26 in the invasive component of lung squamous cell 706. carcinoma: Significant correlation with poor prognosis[r] ...
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Downregulation of selenium binding protein 1 is associated with poor prognosis in lung squamous cell carcinoma
... We examined SBP1 protein expression in LSCC tis- sues using western blotting and immunohistochemistry so as to investigate the role of SBP1 in LSCC because of the proteins as the cellular function molecules. Our re- ...
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Neutral tumor evolution in myeloma is associated with poor prognosis
... Although rearrangements at the immunoglobulin (IGH) loci and hyperdiploidy (HRD) are key initiating events in MM oncogenesis, it is likely by inference from the study of other cancers, that the evolutionary history of MM ...
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Galectin 3 is associated with a poor prognosis in primary hepatocellular carcinoma
... Tissue samples, including HCC tumor tissues and adja- cent non-cancerous tissues (n = 44), were obtained from patients who had resection of primary HCC in the Can- cer Center of Sun Yat-sen University between 2011 and ...
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High expression of TAZ indicates a poor prognosis in retinoblastoma
... [21], hepatocellular carcinoma [12] and ovarian cancer [22]. However, whether TAZ is highly expressed in retino- blastoma remains unclear. To obtain more insight into the expression status and clinical significance of ...
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Low expression of LOC285194 is associated with poor prognosis in colorectal cancer
... The LOC285194 gene is 2105 nt in length, located in chr3q13.31, consisting of four exons. LOC285194 is a lncRNA that showed loss of expression in primary osteosarcoma samples and cell lines. In addition, deple- tion of ...
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CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer
... Colorectal cancer (CRC) is one of the most commonly di- agnosed cancers and, in recent years, has been the second leading cause of cancer-related death in China [1]. Surgical resection remains the primary course of ...
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