positive selection
Positive Selection Drives the Evolution of the Acp29AB Accessory Gland Protein in Drosophila
... Civetta and Singh (1998) found that when closely positive selection for the Acp26Aa gene in the D. melano- related species of Drosophila (D. melanogaster and D. gaster-D. simulans comparison (Aguade´ 1998; ...
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Inferring positive selection in humans from genomic data
... Expected patterns of positive selection in the genome: A beneficial mutation may rise quickly under positive se- lection. If the beneficial allele is going to fixation, genetic hitchhiking [46,47] ...
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Positive Selection in Rapidly Evolving Plastid–Nuclear Enzyme Complexes
... 2014a). These questions extend to the entire ACCase com- plex, as we found evidence of gene loss/decay in nuclear- encoded S. paradoxa ACCase genes (i.e., the apparent loss of ACCB1 and pseudogenization of ACCA). In at ...
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Positive selection on hemagglutinin and neuraminidase genes of H1N1 influenza viruses
... that positive selec- tion on position 274 was responsible for the wide spread of the drug-resistant strains of both seasonal and pandemic H1N1 ...of positive selection acting on position 274 ...
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A survey of methods and tools to detect recent and strong positive selection
... Positive selection occurs when an allele is favored by natural ...of positive selection in genomes is achieved by searching for signatures intro- duced by selective sweeps, such as regions of ...
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Detecting the Footprint of Positive Selection in a European Population of Drosophila melanogaster
... C HANGES in the biotic and abiotic environment of tide variation at individual loci on the X chromosome a species often lead to bursts of adaptive changes, revealed levels of variation generally lower in non-Afri- which ...
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POSITIVE SELECTION FOR MATING WITH FUNCTIONAL HETEROKARYONS IN TETRAHYMENA PYRIFORMIS
... Positive selection for successful conjugation can be used in a number of diverse developmental and genetic studies. Appearance of resistant cells in mating mix- lures of functiona[r] ...
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Positive selection of AS3MT to arsenic water in Andean populations
... High concentrations of arsenic in drinking water represent a strong environmental stressor, driving significant adaptive change in the highland populations of the Argentinean Puna. In this study, AS3MT was identified by ...
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Positive selection on a bacterial oncoprotein associated with gastric cancer
... The topology of the phylogenetic tree of the complete H. pylori cagA sequences reproduces the relationships between different human populations around the world (Figure 1), and is consistent with larger scale studies ...
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Positive selection in glycolysis among Australasian stick insects
... under positive selection in the glycolytic pathway The selective pressures acting on a protein-coding DNA sequence can be inferred from the ratio of nonsyno- nymous to synonymous nucleotide substitutions ...
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Positive Selection of Hepatitis Delta Antigen in Chronic Hepatitis D Patients
... chronic hepatitis D (29). The substitution rate was averaged over the entire delta antigen sequence, whereas the positively selected sites were not specified. Anisimova and Yang (2) reported an analysis that allowed ...
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Positive Selection of Caenorhabditis elegans Mutants With Increased Stress Resistance and Longevity
... identify new elements in these pathways, but brute force screens for long-lived mutants are very laborious. Since long-lived animals are postreproductive, it is necessary to replicate populations of candidate mutant ...
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Mapping Sites of Positive Selection and Amino Acid Diversification in the HIV Genome
... of selection pressure: Positive selection was assessed tion, transmitted variants of HIV-1 would be completely using four different codon-based ML substitution models replaced with escape viruses ...
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Migration promotes plasmid stability under spatially heterogeneous positive selection
... We predicted, therefore, that under spatially heterogeneous positive selection, 58 migration from mutualistic to antagonistic patches will stabilize plasmids across the entire landscape [r] ...
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Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2
... The fact that olaparib primarily targets HRR- deficient tumors is also a potential problem due to positive selection for resistant clones in a heterogeneous tumor ecosystem. Most tumors exhibit complex ...
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Positive selection in octopus haemocyanin indicates functional links to temperature adaptation
... natural selection acting on the Octopus haemocyanin ...various selection tests ...assessing positive selection in mollusc haemocyanins are lacking and at least scarce in other ...groups. ...
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Gene Expansion and Positive Selection as Bacterial Adaptations to Oligotrophic Conditions
... ABSTRACT We examined the genomic adaptations of prevalent bacterial taxa in a highly nutrient- and ion-depleted freshwater environment located in the secondary cool- ing water system of a nuclear research reactor. Using ...
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A Novel Combination of Negative and Positive Selection in Artificial Immune Systems
... Negative selection algorithms (NSA) and positive selection algorithm (PSA) are computational models that have been inspired by negative and positive selection of the biological immune ...
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Genealogical Evidence for Positive Selection in the nef Gene of HIV-1
... under positive selection (with $90% posterior probabil- ity) and the amino acid sequence of the SF2 isolate was used as the prototype sequence for compari- son (X ...
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Detecting Amino Acid Sites Under Positive Selection and Purifying Selection
... is positive results when analyzing sequences that, in truth, controllable and that the test is neither liberal nor un- contain large proportions of neutrally, or almost neu- duly ...under positive ...
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