predictive biomarker
Urinary calcium: a promising predictive biomarker for early recognition of environmental lead exposure in children
... early predictive biomarker of lead exposure and toxicity in children and could be used as a rapid assessment tool for the early detection of significant environmental lead exposure and toxicity in the ...
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Oliguria as predictive biomarker of acute kidney injury in critically ill patients
... It is important to note that Risk, Injury, Failure, Loss, End-Stage (RIFLE) and Acute Kidney Injury Network (AKIN) consensus definitions of AKI incorporate lengthy periods of oliguria (6, 12, and 24 hours) by which time ...
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Exploration of tumour-infiltrating lymphocytes as a predictive biomarker for adjuvant endocrine therapy in early breast cancer.
... a predictive biomarker for the type of adjuvant endocrine therapy in postmenopausal patients with early breast ...a predictive capacity of CD8- positive TILs for endocrine ...
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Early2 factor (E2F) deregulation is a prognostic and predictive biomarker in lung adenocarcinoma
... a biomarker in lung adenocarcinoma ...prognostic biomarker in five FF-based cohorts and two FFPE-based ...a predictive biomarker in two randomized clinical trials; JBR10 and the NATCH ...
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MRE11 as a Predictive Biomarker of Outcome After Radiation Therapy in Bladder Cancer.
... a predictive biomarker in bladder cancer treated with cisplatin-based ...a predictive biomarker in risk-adapted MIBC clinical trials ...
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<p>Monitoring Value of Serum HER2 as a Predictive Biomarker in Patients with Metastatic Breast Cancer</p>
... results ” in breast cancer patients. Multinomial logistic regression analysis was conducted to evaluate the serum HER2 as a metastasis-predictive biomarker in patients with breast cancer. The diagnostic ...
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PD-L1 expression as predictive biomarker in patients with NSCLC: a pooled analysis
... [23, 24]. Even more exciting was the overall survival (OS) benefit obtained with Nivolumab in this setting of patients, leading to the approval of the first anti-PD-1 MoAb, by the Food and Drug Administration (FDA), for ...
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XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy
... XRCC2 has been shown to increase the radioresistance of some cancers. Here, XRCC2 expression was investigated as a predictor of preoperative radiotherapy (PRT) treatment response in locally advanced rectal cancer (LARC). ...
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Circulating cell-free DNA as a prognostic and predictive biomarker in non-small cell lung cancer
... Circulating cell-free DNA (cfDNA), which can be obtained from plasma or serum by non-invasive procedures, has showed great potential to predict treatment response and survival for cancer patients. Several studies have ...
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Circulating fibrinogen is a prognostic and predictive biomarker in malignant pleural mesothelioma
... a predictive value of median fibrinogen in our study ...a predictive biomarker, indicating benefit achieved by surgery as part of the multimodality treatment ...
7
Thymidylate synthase expression as a predictive biomarker of pemetrexed sensitivity in advanced non-small cell lung cancer
... In conclusion, our study carried out using qPCR assay reveals that the TYMS gene was predominantly overex- pressed in these routine clinical samples, and that TYMS overexpression correlated with reduced response to ...
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CCNE1 Amplification as a Predictive Biomarker of Chemotherapy Resistance in Epithelial Ovarian Cancer
... Conversely, while not exactly a study of CCNE1 amplification per se, another study found that cyclin E1 overexpression did not correlate with pathologic response to neoadjuvant chemotherapy [52]. Saponzik et al. [52] ...
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Strategies for power calculations in predictive biomarker studies in survival data
... positive biomarker, treatment and control in negative ...for predictive biomarker validation so investigators can easily incorporate into their study ...
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Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets
... of predictive biomarkers of individual patient response to anti-cancer ...reliable predictive biomarkers to approved agents with anti-angiogenic activity for which no reliable predictive biomarkers ...
10
A three gene signature as potential predictive biomarker for irinotecan sensitivity in gastric cancer
... potential predictive biomarker for cisplatin and docetaxel sensitivity [7,8], thymidylate synthase (TS) for 5-FU and raltitrexed [9,10], and excision repair cross-complementing 1 (ERCC1) for platinum ...as ...
12
Original Article Clinical significance of serum miR-31 as a predictive biomarker for lung adenocarcinoma
... Similarly, miR-31 played an oncogenic role in head and neck squamous cell carcinoma and ARID1A was identified as its downstream target [15]. The expression of miR-31 was significantly upregulated in submucosally invasive ...
7
Abundance of mitochondrial superoxide dismutase is a negative predictive biomarker for endometriosis associated ovarian cancers
... significantly predictive of the prognosis, after dividing into each category of FIGO clinical stage or histological ...a predictive bio- marker for ...
7
H3K27me3 Protein Is a Promising Predictive Biomarker of Patients’ Survival and Chemoradioresistance in Human Nasopharyngeal Carcinoma
... In our study, further correlation analysis re- vealed that high expression of H3K27me3 in NPCs was associated closely with tumor T classification, N classification, distant metastasis an[r] ...
9
Bioinformatics-based identification of miR-542-5p as a predictive biomarker in breast cancer therapy
... were predictive of treatment outcome in a cohort of ERα + breast cancer patients receiving adjuvant tamoxi- fen mono-therapy [13]; miR-519a confers TamR by tar- geting a network of tumor-suppressor genes in ER α + ...
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Protein Carbonyl Content Is a Predictive Biomarker of Eccentric Left Ventricular Hypertrophy in Hemodialysis Patients
... As shown in Table 3, the incidence of eccentric LVH increased progressively from the lowest ( ≤ 3.49 mmol/g of protein) to intermediate (3.50–5.85 mmol/g of protein) and highest baseline PC tertile (>5.85 mmol/g of ...
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