preneoplastic lesions.
Preneoplastic lesions of the lung
... bronchial lesions (although to date, the specificity is relatively ...histologic preneoplastic lesions, however, we still do not know the risk of ...histologic lesions may be reversible if ...
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Original Article Tea polyphenols prevent lung from preneoplastic lesions and effect p53 and bcl-2 gene expression in rat lung tissues
... lung preneoplastic lesions using the lung carcinoma model established by 3,4-benzopyrene intra-pulmonary ...preneoplasm lesions, possibly through regulating the expression of some critical genes such ...
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Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells
... preneoplastic lesions overexpress CD80 and HLA ABC molecules compared to normal and tumor-derived CEC fosters the hypothesis that dysplastic cells can be recog- nized and eliminated in human sporadic ...
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Concordant morphologic and gene expression data show that a vaccine halts HER 2/neu preneoplastic lesions
... While much experimental data shows that vaccination efficiently inhibits a subsequent challenge by a transplantable tumor, its ability to inhibit the progress of autochthonous preneoplastic lesions is ...
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Protective Effects of Epigallocatechin Gallate on Colon Preneoplastic Lesions Induced by 2-Amino-3-Methylimidazo(4,5-f)Quinoline in Mice
... colon cancer could be induced by short- term and flushing-dose IQ. In the current work, we found treatment with IQ for 2 wks to be significantly more effective in inducing ACF than the same amount of carcinogen ...
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Chemopreventive effect of Copaifera langsdorffii leaves hydroalcoholic extract on 1,2 dimethylhydrazine induced DNA damage and preneoplastic lesions in rat colon
... neoplastic lesions of the colonic mucosa, the aberrant crypt foci (ACF), are one of the early morphological changes on the DMH-stimulated colonic mucosal surface in rodents ...
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Hepatitis B Virus X Protein Acts as a Tumor Promoter in Development of Diethylnitrosamine-Induced Preneoplastic Lesions
... In summary, a strong correlation exists between HBV status, exposure to environmental carcinogens, and the development of HCC (10, 57). In the present study, we demonstrate that the expression of HBx in vivo leads to a ...
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Inhibitory effects of astaxanthin on azoxymethane-induced colonic preneoplastic lesions in C57/BL/KsJ-db/dbmice
... Obesity and chronic inflammation are often accom- panied with increased generation of reactive oxygen spe- cies (ROS), which are derivatives of molecular oxygen such as superoxide and hydrogen peroxide. These deriv- ...
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hTERT, MYC and TP53 deregulation in gastric preneoplastic lesions
... To our knowledge, few studies evaluated the number of copies of TP53 in pre-neoplastic gastric lesions. Loss of heterozygosity at the TP53 locus is one of the most common mechanisms involved in this gene pathway ...
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Effect of Rumex Abyssinicus on preneoplastic lesions in dimethylhydrazine induced colon carcinogenesis in rats
... All the rats that received the carcinogen developed the pre-neoplastic lesions (N = 15). In the DMH only group (G-II), the mean ± standard deviation (SD) of ACs, ACF and crypt multiplicity was 103.60 ± 21.04, ...
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YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention
... generating preneoplastic lesions in YB-1 transgenic mice can take 6-8 months (that is following the time-intensive effort of establishing the transgenic mouse ...a preneoplastic stage of breast ...
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Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine
... Among PN-[Epith] cell lines, the first significant Cdh1 expression loss occurred between the Sbnl and PNep subgroups, preceding the increase in expression of both Tgfβ1 and Acta2 in the two PNint cell lines, suggesting a ...
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Original Article Institutional experience in the histopathological characteristics and frequency of gallbladder lesions
... The study included 1841 cases in which chole- cystectomy materials were examined between March 2006 and May 2015 at Dicle University Faculty of Medicine, Pathology Department. Age, gender, year of surgery, diagnosis ...
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Effect of Productive Human Papillomavirus 16 Infection on Global Gene Expression in Cervical Epithelium
... ABSTRACT Human papillomavirus (HPV) infection is the world’s most common sexually transmitted infection and is responsible for most cases of cervical can- cer. Previous studies of global gene expression changes induced ...
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Imageology features of different types of multifocal choroiditis
... active lesions is the retention of subretinal ...66.7% lesions have such exudative manifestations, and the remaining ...of lesions do not have subretinal fluid retention ...inflammatory ...
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Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice
... RESULTS Heterogeneous expression of p53 R172H protein in morphologically normal adult mouse tissues R172H mutant p53 protein mutp53 levels may be elevated in preneoplastic cells, therefo[r] ...
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Protective Effect of Ethanolamine on Hepatic Preneoplastic Alterations Induced by the Administration of N Nitrosodiethylamine in Rats
... hepatic lesions in rats were ...hepatic lesions were assessed according to the number of nodules detectable on the liver surface, areas of clear cell foci observed on histopathological thin sections, ...
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Cortical Lesions in Multiple Sclerosis: Combined Postmortem MR Imaging and Histopathology
... intracortical lesions (types II–IV), which are difficult to visualize with MR im- aging, do not show substantial T lymphocyte infiltra- ...GM-WM lesions, which are better detectable with MR imaging, do ...
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Mutations in the K ras oncogene induced by 1,2 dimethylhydrazine in preneoplastic and neoplastic rat colonic mucosa
... These experiments were conducted to determine whether point mutations activating K-ras or H-ras oncogenes, induced by the procarcinogen 1,2-dimethylhydrazine (DMH), were detectable in preneoplastic or neoplastic ...
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Diagnostic accuracy of blood sucrose as a screening test for equine gastric ulcer syndrome (EGUS) in weanling foals
... gastric lesions prior to weaning was 21% and increased to a staggering 98% within 2 weeks of ...bleeding lesions with areas of apparent deep ulceration characteristic of EGUS severity score 4 ...
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