Primary progressive
Development, Cross-Cultural Adaptation, and Psychometric Characteristics of the Persian Progressive Aphasia Language Scale in Patients With Primary Progressive Aphasia: A Pilot Study
... of primary progressive aphasia is associated with a different anatomical site of peak atrophy in the left-hemisphere language net- work: the inferior frontal gyrus (Boca’s area) in the agrammatic variant, ...
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Magnetic resonance imaging evaluation and therapeutic trials in primary progressive multiple sclerosis
... with primary progressive multiple ...the primary clinical endpoint though there was a suggestion of a differential effect on one of the secondary clinical outcomes, the ...
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Single-word comprehension deficits in the nonfluent variant of primary progressive aphasia
... in primary progressive apraxia of speech, a syndrome which shows underlying FTLD tauopathy at postmortem examination [12] and elevated retention of the tau PET tracer [ 18 F]-AV1451 in the supplementary ...
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Behavioural and neuroanatomical correlates of auditory speech analysis in primary progressive aphasias
... Background: Non-verbal auditory impairment is increasingly recognised in the primary progressive aphasias (PPAs) but its relationship to speech processing and brain substrates has not been defined. Here we ...
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Classification of the primary progressive aphasias: principles and review of progress since 2011
... Highly influential recommendations published in 2011 for the classification of the primary progressive aphasias (PPA) distinguished three subtypes: the semantic variant, the nonfluent/agrammatic variant, ...
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Thalamic Iron Differentiates Primary Progressive and Relapsing Remitting Multiple Sclerosis
... subtypes. Primary-progressive MS (PPMS) is a subtype characterized by a steady progression with- out relapses and worse response to immunosuppressant ...
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Functional MR Imaging Correlates of Neuropsychological Impairment in Primary Progressive Multiple Sclerosis
... ABBREVIATIONS: ANOVA ⫽ analysis of variance; BOLD ⫽ blood oxygen level– dependent; CC ⫽ corpus callosum; CI ⫽ cognitively impaired; CMA ⫽ cingulate motor area; CP ⫽ cognitively preserved; EDSS ⫽ Expanded Disability ...
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Thalamic Damage Predicts the Evolution of Primary Progressive Multiple Sclerosis at 5 Years
... ABBREVIATIONS: CI ⫽ confidence interval; DTI ⫽ diffusion tensor imaging; EDSS ⫽ Expanded Disability Status Scale; FA ⫽ fractional anisotropy; GM ⫽ gray matter; LV ⫽ lesion volume; MD ⫽ mean diffusivity; MS ⫽ multiple ...
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Progression of logopenic variant primary progressive aphasia to apraxia and semantic memory deficits
... The areas of the brain that are primarily affected in the present cases may account for the development of apraxia and semantic memory deficits. The main location of lesions in lvPPA, but not naPPA or svPPA, involves ...
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Treating primary-progressive multiple sclerosis: potential of ocrelizumab and review of B-cell therapies
... in progressive MS, as well as rituximab’s effect in subgroup analysis of PPMS patients, a Phase III trial has been conducted using ocrelizumab for primary progressive multiple sclerosis ...presence). ...
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Brain atrophy in primary progressive aphasia involves the cholinergic basal forebrain and Ayala's nucleus
... Primary progressive aphasia (PPA) is characterized by left hemispheric fronto-temporal cortical atrophy. Evidence from anatomical studies suggests that the nucleus subputaminalis (NSP), a subnucleus of the ...
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Can MRI Visual Assessment Differentiate the Variants of Primary Progressive Aphasia?
... semantic-variant primary-progressive aphasia and low sensitivity (21% for nonfluent-variant primary-progressive aphasia and 43% for logopenic-variant primary-progressive aphasia) ...
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Retained capacity for perceptual learning of degraded speech in primary progressive aphasia and Alzheimer’s disease
... variant primary progressive aphasia, M Male, MMSE Mini Mental State Examination [57], N Normal, NA, Not available, nfvPPA Patient group with non-fluent variant primary progressive aphasia, ...
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Frontotemporal networks and behavioral symptoms in primary progressive aphasia
... Differences in tract-specific measurements of the uncinate fasciculus (UF), inferior fronto-occipital fasciculus (IFOF), and inferior longitudinal fasciculus (ILF) between controls and patients with primary ...
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[18F]THK-5351 PET imaging in early-stage semantic variant primary progressive aphasia: a report of two cases and a literature review
... variant primary progressive aphasia; TDP43: Transactivation responsive region DNA-binding protein of 43 Kda; VPTA: Visual Perception Test for Agnosia; VSRAD: Voxel-Based Specific Regional Analysis System ...
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Primary progressive apraxia: an unusual ideomotor syndrome
... slow progressive limb kinetic apraxia, Otsuki et al [14], described a patient with an MRI show- ing left parietal atrophy and left pre- and post-central gyrus ...and progressive inability to dress or to use ...
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The ‘Better Conversations with Primary Progressive Aphasia (BCPPA)’ program for people with PPA (Primary Progressive Aphasia): protocol for a randomised controlled pilot study
... with primary progressive aphasia and their conversation partners across seven UK National Health Service ...with Primary Progressive Aphasia ’ intervention (21 couples) or no speech and ...
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Frontotemporal dementia and primary progressive aphasia, a review
... Abstract: Frontotemporal dementias are neurodegenerative diseases in which symptoms of frontal and/or temporal lobe disease are the first signs of the illness, and as the diseases progress, they resemble a focal left ...
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The MRZ reaction in primary progressive multiple sclerosis
... exhibit primary progressive MS (PPMS), characterised by a continuous worsening of symptoms from the onset, when patients are typically between 30 and 50 years old [1, ...
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Quantification of motor speech impairment and its anatomic basis in primary progressive aphasia
... The Progressive Aphasia Severity Scale, 18 an instrument used by clinicians to rate degree of impairment (0–3 interval scale) across 10 primary speech and language domains, was used to index severity of ...
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