Prognostic signature
Identification of prognostic signature in cancer based on DNA methylation interaction network
... our prognostic genes in the train- ing data set shows these genes can distinguish the progno- sis of tumor samples, with a HR (hazard ratio) of ...the prognostic signature is ...trol signature ...
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<p>Development and Validation of a Novel 8 Immune Gene Prognostic Signature Based on the Immune Expression Profile for Hepatocellular Carcinoma</p>
... struct prognostic marker models for HCC, including one that utilized 6 genes based on the TCGA cohort, 18 and another the utilized 3 genes (UPB1, SOCS2, and RTN3) from the same ...A prognostic ...
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Identification of an eight-gene prognostic signature for lung adenocarcinoma
... the prognostic value of the ten hub genes selected by PPI, the Kaplan–Meier plotter was applied to the patient data in the TCGA ...the prognostic value of the eight genes in LUAD patient survival, we ...
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A robust prognostic signature for hormone-positive node-negative breast cancer
... the signature was built from the largest training dataset available to date; (2) patients with HER2+ tumors were ex- cluded, thus focusing only on patients without an existing clear treatment course; (3) the gene ...
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Development and validation of a prognostic signature for preoperative prediction of overall survival in gastric cancer patients
... Eleven-lncRNA signature scores of patients in the validation group were calculated accord- ing to the original formula of Eleven-lncRNA signature in the model ...Eleven-lncRNA signature score (Figure ...
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An individualized immune prognostic signature in lung adenocarcinoma
... independent prognostic factor in MVA, after adjusting for clinical characteristics such as age, gender, TNM stage and purity in validation dataset-1 (HR ...
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Development of a prognostic composite cytokine signature based on the correlation with nivolumab clearance: translational PK/PD analysis in patients with renal cell carcinoma
... surrogate prognostic biomarker [14, 19, ...eight-cytokine prognostic signature for RCC, via correlation with clearance, is a highly practical way to utilize this robust ...
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A 41-gene signature derived from breast cancer stem cells as a predictor of survival
... The prognostic signature is also a strong predictor of OS in patients with lymph node negative disease in this ...a prognostic signa- ture predicting the survival and recurrence of breast cancer ...
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A methylation‐based mRNA signature predicts survival in patients with gastric cancer
... All datasets and clinical information, as described in Table 1 and Additional file 1: Table S1, were down- loaded from the GEO (https ://www.ncbi.nlm.nih.gov/ geo/) and TCGA (https ://cance rgeno me.nih.gov/). Gene ...
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Identification of a m6A RNA methylation regulators-based signature for predicting the prognosis of clear cell renal carcinoma
... two-gene signature, METTL3 and METTL14, serving as an independent prognostic indicator for distinguishing ccRCC patients with different prognosis both in training, validation and our own clinical ...the ...
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Prognostic value and their clinical implication of 89-gene signature in glioma
... 129 genes whose expression was tightly associated with the two groups were selected (Supplementary Figure S2). Because 89 genes were common among all training and validation data sets, they were used as prognostic ...
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Prognostic value of a five-lncRNA signature in esophageal squamous cell carcinoma
... their area under the curve (AUC) values to screen out the prognostic signature with the largest AUC value in the GSE53624 set [28]. The whole construction process was shown in Additional file 2. Figure S1. ...
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Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases
... a prognostic signature based on the expression level of PDE4D1/2 relative to the sum of the expression levels of the long PDE4D5, PDE4D7 and PDE4D9 isoforms ...this signature was then evaluated in ...
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Genome wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis
... the prognostic signature was signifi- cantly associated with survival in both data sets (P < ...the prognostic signature, lymph node status was signifi- cantly associated with survival in ...
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Prognostic value of a 92-probe signature in breast cancer
... the prognostic gene candidates, we used the univariate Cox regression to generate hazard ratio using the Cox regression coefficient of each probe in the prognostic ...the prognostic signature ...
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Genomic signatures for predicting survival and adjuvant chemotherapy benefit in patients with non-small-cell lung cancer
... the prognostic signature to predict risk of DSS in patients not involved in the gene selection or training process, it was applied to data from an independent series of 264 lung adenocarcinoma patients with ...
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Identification of four differentially methylated genes as prognostic signatures for stage I lung adenocarcinoma
... pair signature was selected as prognostic signature, which successfully clustered LUAD patients at stage I into high- and low-risk groups with significant ...pair signature were enriched in ...
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Four-miRNA signature as a prognostic tool for lung adenocarcinoma
... four-miRNA signature index that successfully separated patients into low- and high-risk ...four-miRNA signature index had significantly shorter survival times than those in the low-risk group (P = ...
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HSC commitment–associated epigenetic signature is prognostic in acute myeloid leukemia
... this signature was able to classify 3 independent cohorts of patients with AML from prospective clinical trials into groups with superior or significantly inferior ...epigenetic signature score reached ...
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A robust prognostic gene expression signature for early stage lung adenocarcinoma
... expression signature for early stage lung adenocarcinoma. The signature was validated in an inde- pendent cohort, however, with 95 patients in the regres- sion, of which many left the study or were censored ...
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