Promoter Regions (Genetics)
The properties of CpG islands in the putative promoter regions of human immunoglobulin (Ig) genes
... 5’ end of approximately 60% of human genes and so are important genomic landmarks (Cross et al., 2000). Study of occurrence and characteristics of the CpG islands has gained great interests. Whole genome CpG island ...
34
Cross-species comparison of CpG density in the promoter regions of protein kinase oncogenes
... In the present study, we observed first that human PKOs with a relatively high CpG density in the PRs are highly expressed in tumour tissues, consistent with previous studies that high CpGs density in the gene PR is ...
10
Promoter regions of Plasmodium vivax are poorly or not recognized by Plasmodium falciparum
... heterologous promoter analysis was used to determine if P. vivax promoter regions of different sizes and AT-contents are functional in ...upstream regions analyzed, harboring very distinct AT ...
10
Analysis of epigenetic alterations in the promoter regions of TIMP3 and GSTP1 genes in sporadic breast cancer
... as promoter hypermethylation, are often involved decrease expression of tumor suppressor gene which are associated in tumor development, progression, and recurrence (Sarkar et ...
8
Identification and expression profiling of Pht1 phosphate transporters in wheat in controlled environments and in the field
... OsPht1;6 promoter contains also two W-boxes very close to each other (20 nucleotides, data not shown) which are also present in comparable location in the promoter of the B- and D-genome TaPht1;6 genes just ...
16
Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis
... at promoter and non-promoter regions when compared to non- responsive and gene length-matched ...binding regions were found to be nonfunctional in transactivating luciferase reporters ...
17
Clinical Significance of Hepatitis B Virus (HBV) Genotypes and Precore and Core Promoter Mutations Affecting HBV e Antigen Expression in Taiwan
... core promoter regions were determined from sera collected at the last visit for asymptomatic carriers and at the time of liver biopsy for patients with chronic hepatitis and ...
7
Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.
... By using various fragments and deletion constructs, this promoter activity 3269 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest To identify promoter regions which contr[r] ...
11
Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study
... to promoter regions of the CRP gene, down stream of the IL-6 responsive site, is known to be involved in synergistic trans-activation of CRP promoter ...CRP promoter caused by increased ...
6
Characterisation of keratin genes associated with wool traits
... KRT83 promoter and KRT85 Promoter 1 regions investigated, to five variants for the KRT83 exon 3 – 4 ...the regions amplified had two ...in promoter regions or intron ...
123
oa Journal of Applied Science in Southern Africa - Cloning, sequencing and expression of an endo-?-1,4- glucanase gene of a Bacillus subtilis CHZ1
... in promoter regions of Bacillus alkaline endoglucanase ...The promoter elements are, the –35 and –10 regions upstream from the potential transcription start codons, the spacer DNA separating ...
11
Genes implicated in multiple sclerosis pathogenesis from consilience of genotyping and expression profiles in relapse and remission
... sequence: 5'-AGCCTCTGTGCTCCAGAATC-3' and reverse primer sequence: 5'-GGCTGAGGTAGATGTAGTCGTCA- 3'. TGFβ1 (R36467) forward primer sequence: 5'- GGGAGGTGCTCAGTAAAGG-3' and reverse primer sequence: 5'-CTCGCTGTCTGGCTGCTC-3'. ...
12
ADMIRE: analysis and visualization of differential methylation in genomic regions using the Infinium HumanMethylation450 Assay
... genomic regions and gene sets: 2-kB promoter regions and positional gene sets for the rheumatic arthri- tis (RA) data and 5- and 10-kB genomic tiling regions for the atrial fibrillation (AF) ...
10
Crimean-Congo Hemorrhagic Fever Virus-Encoded Ovarian Tumor Protease Activity Is Dispensable for Virus RNA Polymerase Function
... Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonosis. Human infections are associated with a rapidly progressive acute febrile illness with high case fatality (10). CCHF outbreaks occur on a frequent ...
11
Multiplex PCR and next generation sequencing for the non invasive detection of bladder cancer
... analyse FGFR3 mutations in urinary DNA [16] and to analyse TERT promoter mutations in urinary DNA [17], we have now developed a method enabling a single analysis to measure both urinary biomarkers and others. It ...
12
Clinical application of next-generation sequencing for Mendelian diseases
... multiple regions of the genome in one single reaction and has been shown to be a cost-effective and efficient tool in investigating patients with Mendelian ...of genetics in everyday ...
6
Genomic association study for age at first calving and calving interval in Romosinuano and Costeño con Cuernos cattle
... In ROMO, a total of 17 SNP windows that explained 0.13% of the genetic variance for AFC as a whole were identified in chromosomes BTA1, BTA2, BTA5, BTA10, BTA14, BTA15, BTA16, BTA17, BTA21, BTA22, BTA24, and BTA29 ...
13
Efficient Rescue of Recombinant Lassa Virus Reveals the Influence of S Segment Noncoding Regions on Virus Replication and Virulence
... After the successful generation of recombinant wtLASV (rLASV), we utilized this robust system to study the role of the 5 ⬘ and 3 ⬘ NCRs in the virus replication cycle. The composition of the minimum promoter ...
5
Identification of a Movement Protein of the Tenuivirus Rice Stripe Virus
... Constructs and procedures for complementation experiments. The move- ment-defective PVX tagged with the -glucuronidase (GUS) gene (pPVX.GUS- Bsp) (27) was used for complementation experiments. Construct pBI-P25, ex- ...
8
Targeted Gene Replacement in Drosophila Goes the Distance
... The two articles in this issue of Genetics take conceptually similar approaches to making gene targeting in Drosophila more efficient. First, by making use of previously integrated sequence-specific recombinase ...
5