Prostaglandin E1
Stimulation of osmotic water flow in toad bladder by prostaglandin E1 Evidence for different compartments of cyclic AMP
... of prostaglandin E1 (PGE1) on osmotic water flow across toad bladder and cyclic AMP content of the mucosal epithelial cells has been determined under basal conditions and in the presence of either ...
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Examining Endothelial Dysfunction and The Effect of Topical Treatment with Prostaglandin E1 In Diabetics Suffering from Erectile Dysfunction
... The active ingredient is alprostadil 300 µg, the pharmaceuti- cal equivalent of endogenous prostaglandin E1 (PGE1). Alprosta- dil acts independently of the psychological and neurological com- ponents of the ...
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Vasodilative effects of prostaglandin E1 derivate on arteries of nerve roots in a canine model of a chronically compressed cauda equina
... One week after this procedure, 3 μg/kg with 10 ml normal saline OP-1206 OP-1206α-CD cyclodextrin clathrate (OP-1206α-CD), a prostaglandin E1 derivative, was administrated orally and the studies described ...
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Effect of prostaglandin E1 on the permeability response of the isolated collecting tubule to vasopressin, adenosine 3′,5′ monophosphate, and theophylline
... The effect of prostaglandin E1 PGE1 on the water permeability response to vasopressin, theophylline, and cyclic adenosine 3¢,5¢-monophosphate C-AMP of isolated, perfused collecting tubul[r] ...
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To Intubate or Not to Intubate? Transporting Infants on Prostaglandin E1
... 15. Browning Carmo KA, Barr P, West M, Hopper NW, White JP, Badawi N. Transporting newborn infants with suspected duct dependent congenital heart disease on low-dose prostaglandin E1 without routine ...
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Chloride secretory mechanism induced by prostaglandin E1 in a colonic epithelial cell line
... M prostaglandin E1; the increase in serosal to mucosal Cl- flux exceeded the increase in mucosal to serosal flux, resulting in net Cl- ...of prostaglandin E1 on ion fluxes was tested in the ...
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Original Article Protective effects of ulinastatin combined with nitric oxide and prostaglandin E1 on lung injuries and coagulation in infants undergoing cardiopulmonary bypass
... en recognized as major contributors to bleed- ing after the operation. Granule membrane pro- tein 140 (GMP-140) has been identified as a platelet glycoprotein, mainly located on the membrane of blood platelet [41]. When ...
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Therapeutic Effects of Carbogen Inhalation and Lipo Prostaglandin E1 in Sudden Hearing Loss
... Purpose: Vascular disorders and viral infections are considered the main causes of sudden hearing loss (SHL), although its pathogenesis remain unclear. Treatments include carbogen inhalation and lipo-prostaglandin ...
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Enhanced Effects of Prostaglandin E1 and Dibutyryl Cyclic AMP upon Human Lymphocytes in the Presence of Cortisol
... Incubation with prostaglandin E1 PGE1, dibutyryl cyclic AMP, or cortisol results in a concentration-dependent inhibition of [3H]-thymidine incorporation by both unstimulated and phytohem[r] ...
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Original Article Effect of prostaglandin E1 in patients with advanced lung cancer treated with chemotherapy
... Abstract: To examine potential VTE risk reducing effect of prostaglandin E1 (PGE1) as supplemental therapy in patients with advanced lung cancer treated by chemotherapy.68 patients were recruited in this ...
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Effects of prostaglandin E1 on callus formation in rabbits
... Prostaglandin E1 (PGE1) has general vasodilatory, anti- thrombotic and endothelium-stabilizing properties. This is thought to be due to the activation of neutrophil leu- kocytes and thrombocytes, inhibition ...
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Prostaglandin E1 inhibits effector T cell induction and tissue damage in experimental murine interstitial nephritis
... underlying prostaglandin E1 (PGE1)-associated immunosuppression in autoimmunity, we treated SJL mice immunized to produce immune-mediated interstitial nephritis with PGE1, PGF2 alpha, or vehicle ...
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Prostaglandin E1 abrogates early reductive stress and zone specific paradoxical oxidative injury in hypoperfused rat liver
... with prostaglandin E1 not only abrogated an early increase in pyridine nucleotide fluorescence and mitochondrial dysfunction induced by hypoperfusion but also diminished the subsequent midzonal oxidative ...
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Prostaglandin E1 Combined with Chitosan Conduit Improves Sciatic Nerve Regeneration in Rats
... Forty-five male white Wistar rats weighing approximately 290 g and 3 months age were divided into four experimental groups (n=15), randomly: Sham- operation (SHAM), control (CHIT) and prostaglandin treated ...
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Effects of vasopressin and prostaglandin E1 on the adenyl cyclase—cyclic 3′,5′ adenosine monophosphate system of the renal medulla of the rat
... In the inner medulla 10-' M PGE1, which alone had no effect on cyclic AMP concentration, decreased the effect of submaximal vasopressin, 10- U/ml, to increase tissue cyclic AMP concentra[r] ...
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Prolonged Prostaglandin E1 Infusion in an Infant With Cyanotic Congenital Heart Disease
... venous sites had been used during the previous month, infiltration of the ductus arteriosus with 10% buffered. formalin was undertaken[r] ...
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Prolonged Prostaglandin E1 Infusion: Histologic Effects on the Patent Ductus Arteriosus
... Histologic examination of the normally closing ductus in patients with untreated ductus-dependent heart disease and of ductus from normally devel- oped hearts has been reported to show t[r] ...
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Effects of Ca++ and Prostaglandin E1 on Vasopressin Activation of Renal Adenyl Cyclase
... Adenyl cyclase activity was assayed in crude homogenates of the renal cortex, medulla, and papilla of the golden hamster. The specific activity (moles C-AMP/unit of time per mg protein of tissue) of the enzyme under ...
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Mechanism of the Lower Esophageal Sphincter Relaxation ACTION OF PROSTAGLANDIN E1 AND THEOPHYLLINE
... The intravenous injection of prostaglandin E 1 (PGE 1 ) causes a dose-dependent relaxation of the lower esophageal sphincter (LES) in the intact, lightly anesthetized opossum. The action of PGE 1 is not inhibited ...
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Ductus Arteriosus Dilatation by Prostaglandin E1 in Infants With Pulmonary Atresia
... vasodilatation.I@2 We were concerned that systeiiiic vasodilatation in these infants with severe cyanotic congenital heart disease may result in a significant fall in systemic arterial b[r] ...
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