Prostaglandin production
Hydrogen peroxide stimulates rat colonic prostaglandin production and alters electrolyte transport
... PGI2 production 8- and 15-fold, respectively, inhibited neutral NaCl absorption, and stimulated biphasic electrogenic Cl secretion with little effect on enterocyte lactic dehydrogenase release, epithelial ...
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Captopril induced Changes in Prostaglandin Production: RELATIONSHIP TO VASCULAR RESPONSES IN NORMAL MAN
... on prostaglandin production, because changes in neither the renin-angiotensin nor the kallikrein-kinin systems appear adequate to account for the fall in arterial ...
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Phospholipase A2 regulation of bovine endometrial (BEND) cell prostaglandin production
... Cells were grown in 6-well plates, washed three times with HBSS and cultured for 6 h in unsupplemented Ham's F- 12/MEM with the following treatments: vehicle control, PDBu (100 ng/ml), IFNT (50 ng/ml), the PLA2G6 inhibi- ...
9
Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production
... fibroblast prostaglandin E(PGE) synthesis (20- to ...of prostaglandin synthesis (indomethacin, meclofenamate, and eicostaetraynoic acid), and (c) was reproduced by addition of exogenous PGE2 to fibroblast ...
13
Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation
... cycloheximide abolished the release of NO2- and attenuated the exaggerated BK-induced PGE2 production. This supports the existence of iNOS and COX-2 in the HNK. In the CLK, BK elicited release of both NO2- and ...
9
Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors
... We have recently put forward the hypothesis that the dual inhibition of proinflammatory nitric oxide (NO) and prostaglandins (PG) may contribute to the antiinflammatory properties of nitric oxide synthase (NOS) ...
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Increased prostaglandin production by glomeruli isolated from rats with streptozotocin induced diabetes mellitus
... whereas production of thromboxane B2 (TXB2) was not significantly greater than ...PG production did not appear to be related directly to the severity of the diabetic state as reflected by the degree of ...
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BVDV alters uterine prostaglandin production during pregnancy recognition in cows
... Bovine uterine endometrial cells isolated from 10 BVDV free cows were 29.. cultured and treated with 0 or 100 ng/ml interferon-tau (IFNT) in the absence or presence of non- 30.[r] ...
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Adenovirus Triggers Reorganization of Vimentin-Containing Intermediate Filaments Resulting in the Perinuclear Movement of cPLA2 and Suppression of Prostaglandin Production
... Overall, the additional early region gene products assist in viral replication and modulation of the host immune response. The E1B-19kDa and E1B-55kDa proteins are expressed following E1A and are responsible for ...
173
Effect of hydrogen peroxide on prostaglandin production and cellular integrity in cultured porcine aortic endothelial cells
... The effects on cyclooxygenase and PG12 synthase activity were determined by incubating cells with either arachidonic acid, ionophore A23187, or prostaglandin cyclic endoperoxide PGH2 and[r] ...
9
Indomethacin is a Placental Vasodilator in the Dog: THE EFFECT OF PROSTAGLANDIN INHIBITION
... The effect of 8 mg/kg of indomethacin on uterine blood flow, prostaglandin production, and intraamniotic fluid pressure was examined in late pregnant dogs. Uterine blood flow was measured with 15 µm ...
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<p>Prostaglandins as the Agents That Modulate the Course of Brain Disorders</p>
... the production of PGs cyclooxygenase is a necessary enzyme that has two isoforms, that are named COX-1 and ...of prostaglandin production may confer the alleviation of some brain ...
13
Cardiotonic agent milrinone stimulates resorption in rodent bone organ culture
... because prostaglandin production was crucial for the effects of both agents in calvaria but not in limb bones, and neither agent exhibited escape from calcitonin ...
6
Suppression of lymphocyte responses by tuberculous plasma and mycobacterial arabinogalactan Monocyte dependence and indomethacin reversibility
... Indomethacin reversibility of the effect of AG on stimulated DNA synthesis and monocyte adherence to plastic suggested that increased monocyte prostaglandin production mediated the effec[r] ...
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Impacts of Cytosolic Phospholipase A2, 15 Prostaglandin Dehydrogenase, and Cyclooxygenase 2 Expressions on Tumor Progression in Colorectal Cancer
... Purpose: In addition to cyclooxygenase-2 COX-2 which is related to prostaglandin E2 synthesis, other enzymes such as cytosolic phospholipase A2 cPLA2, microsomal prostaglandin E2 synthas[r] ...
8
Statins stimulate arachidonic acid release and prostaglandin I2 production in rat liver cells
... Mevastatin, lovastatin, simvastatin and atorvastatin stim- ulate the release of AA from rat liver cells. They do so even after preincubation with actinomycin. Mevalonate, the product of HMG-CoA reductase, does not ...
9
Interferon gamma induces prostaglandin G/H synthase 2 through an autocrine loop via the epidermal growth factor receptor in human bronchial epithelial cells
... of prostaglandin E2 (PGE2) released in response to stimulation with exogenous arachidonic acid (5 ...enhanced production of PGE2 reflected the upregulation of PGHS-2 as indicated by enhanced expression of ...
8
Effective NSAID treatment indicates that hyperprostaglandinism is affecting the clinical severity of childhood hypophosphatasia
... the prostaglandin synthesis occurring in normal as well as in HP fibroblasts exposed to pyridoxal phosphate and/or calcium pyrophosphate, two of the metabolic products that accumulate in ...
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The effects of 1α,25 dihydroxyvitamin D3 on matrix metalloproteinase and prostaglandin E2 production by cells of the rheumatoid lesion
... MMP production by some cell cultures ...2 production by RSFs, but the enhanced PGE 2 production observed following IL-1 β stimulation of these cells was markedly suppressed by the concomitant ...
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Effects of Litchi chinensis fruit isolates on prostaglandin E2 and nitric oxide production in J774 murine macrophage cells
... NO production in a dose-dependent manner without affecting cell ...NO production was at the range of ...NO production were at the range of ...
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