Prostate cancer stem cell
1 Roles of Extracellular Vesicles (EVs) carrying HSPs in
... Secreted heat shock protein 90 promotes prostate cancer stem cell 545. heterogeneity[r] ...
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The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem–like compartment
... Metastatic prostate cancer represents a yet unsolved clinical problem due to the high frequency of relapse and treatment ...to prostate cancer progression is an important task to prevent this ...
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Role of cancer stem cells in breast and prostate cancer
... that cancer cells did not fully rely on exogenous supply of growth factors for proliferation as these produce a vast amount of peptide growth factors and participate in autocrine secretion (Sporn and Roberts ...
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Enrichment of Prostate Cancer Stem-Like Cells from Human Prostate Cancer Cell Lines by Culture in Serum-Free Medium and Chemoradiotherapy
... The cancer stem cells (CSCs) hypothesis postu- lates that a small subpopulation of cancer cells drive tumor growth and metastasis, and that CSCs are more resistant to toxic injuries and ...
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An Artificial Niche for Circulating Endothelial Cells During Tumor Angiogenesis Mediated by Prostate Cancer Stem Cells
... above cell population, CD133- positive and VEGFR2-positive cells were obtained by positive selection with CD133 and VEGFR2 immunomagnetic microbeads using an auto– magnetic cell sorting cell ...
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Insights into Chemoresistance of Prostate Cancer
... CRPC cell origin are incom- pletely understood, which partially explains why the CSC concept has attracted much ...First, cell surface markers on PCSCs may be co-expressed by non-cancer stem ...
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Mesenchymal stem cell-mediated delivery of therapeutic adenoviral vectors to prostate cancer
... and cell-based vectors have engi- neered, but most have shown low practical efficiency ...Mesenchymal stem cells are attractive vehicles for gene therapy due to their outstanding ability to migrate towards ...
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Dual-Modality ImmunoPET/Fluorescence Imaging of Prostate Cancer with an Anti-PSCA Cys-Minibody
... for prostate cancer lead to over- and undertreatment, and the inability to intraoperatively visualize positive margins may limit the success of surgical ...resection. Prostate cancer ...
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CD54-NOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer
... Cancer stem cells (CSCs) are considered one of the key contributors to chemoresistance and tumor ...to cancer biology. Here, we implemented a novel chemoresistant prostate cancer ...
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Original Article Gli1, a potential cancer stem cell marker, is strongly associated with prognosis in prostate cancer
... of cancer stem-like cells (CSCs) in prostate cancer (PCa) is ...with cancer stemness genes, cell cycle markers, epithelial-mesenchymal transition (EMT), and signaling pathway ...
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Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer
... T cell activation and transducts signals through src-like tyrosine kinases ...in cell- cell adhesion [23-25]. Cell-cell or cell-matrix interaction is critical for local tumor ...
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The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer
... of prostate cancer and osteoblasts as DTCs compete for the occupancy of the osteoblastic niche [2], although certainly other components of the HSC niche are also ...direct cell- to-cell ...
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Quantification of Mesenchymal Stem Cells (MSCs) at Sites of Human Prostate Cancer
... Mesenchymal Stem Cells (BM-MSCs) have an innate tropism for tumor tissue in response to the inflammatory microenvironment present in malignant ...The prostate is bombarded by numerous infectious & ...
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Steroidogenic Enzymes and Stem Cell Markers Are Upregulated during Androgen Deprivation in Prostate Cancer
... We thank Gerald Verhaegh for proof- reading the manuscript with valuable scientific criticism, Maureen Völler for excellent laboratory support, Eugène Verwiel (department of human genetics) for Affymetrix GeneChip gene ...
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RETRACTED ARTICLE: Umbilical cord tissue-derived mesenchymal stem cells induce apoptosis in PC-3 prostate cancer cells through activation of JNK and downregulation of PI3K/AKT signaling
... Next, we investigated the homing of hUCMSCs to PC-3 cells in mice. PC-3 cells were injected subcutaneously into the left flank of the Balb-c/ nu-nude mice. Two weeks later, PKH26-labeled hUCMSCs were transplanted into ...
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<p>Bruton’s Tyrosine Kinase (BTK) Inhibitor (Ibrutinib)-Suppressed Migration and Invasion of Prostate Cancer</p>
... of prostate cancer, especially in the cancers with bone ...of prostate cancer cells and suggested that BTK could serve as not only a potential biomarker for diagnosis and prognosis but also a ...
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Original Article Silencing of CCR7 inhibits the growth, invasion and migration of prostate cancer cells induced by VEGFC
... PC-3 prostate cancer cell proliferation in the presence of VEGFC, the MTT assay was used and cell proliferation was determined by count- ing the number of viable ...PC-3 prostate ...
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Inhibition of Prostate Cancer Cell Colony Formation by the Flavonoid Quercetin Correlates with Modulation of Specific Regulatory Genes
... Propolis, a resinous, alternative medicine derived from pop- lar trees and collected from bees, has been proposed to have antimicrobial and anti-inflammatory activities. In a clinical study, Suzuki and coworkers (33) ...
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EVALUATION OF ANTICANCER PROPERTY OF GOSSYPOL USING HeLa CELL LINE
... the cell line is transferred drop wise into the centrifuge tube containing the thawed ...cells. Cell suspension is centrifuged for 5–10 ...the cell pellet was re- suspended in complete growth medium, ...
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Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function
... B cell lymphoma, and in some human malignancies low TTP expression correlates with reduced ...human prostate cancer. First, gene expression analysis of prostate tumors revealed low TTP ...
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