Prostate cancer stem cells
Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression
... define prostate stem cells (PSCs) as the cells capable of differentiating into single (unipotent) or multiple cell types (multipotent) that form the prostate ...the cancer- ...
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Role of EZH2 in the Growth of Prostate Cancer Stem Cells Isolated from LNCaP Cells
... somatic stem cells for their proliferation and ...in prostate cancer stem cells (PCSCs) remain ...human prostate cancer cell line LNcap by fluorescence activated ...
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Original Article miR-199a and miR-34c enhance the migration of prostate cancer stem cells but inhibit migration of PC3 prostate cancer cells
... Abstract: Cancer stem cells (CSCs) have been identified in several cancers, including prostate cancer ...though prostate cancer stem cells (PCSCs) may ...
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An Artificial Niche for Circulating Endothelial Cells During Tumor Angiogenesis Mediated by Prostate Cancer Stem Cells
... To do so, the CEPs were isolated from human peripheral blood and expanded in an artificial niche using in a transwell plate. The migration, adhesion, homing and differentiation of CEPs towards prostate ...
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Novel regulators of prostate cancer stem cells and tumor aggressiveness
... human prostate cancer ...human prostate cancer ...human prostate cancer cells suggesting a paracrine effect of stroma- derived BMP9 on tumor ...human prostate ...
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Original Article Enrichment of prostate cancer stem cells from primary prostate cancer cultures of biopsy samples
... Most prostate cell line is adherent in vitro, such as PC3, DU145, 22Rv1 and LNCaP, and certain amount of fetal bovine serum is essential for the cells ...epithelial cells, most cells grew big- ...
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Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow
... Recent studies suggest that GAS6 and Mer receptor signaling regulate the cell cycle status of cells as well as the induction of a stem cell phenotype in normal and cancer cells [14–19]. In ...
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Enrichment of Prostate Cancer Stem-Like Cells from Human Prostate Cancer Cell Lines by Culture in Serum-Free Medium and Chemoradiotherapy
... Although once or twice weekly radiation doses of 2 Gy, 4 Gy, 6 Gy, 8 Gy, and 10 Gy were trialed, 4 Gy twice a week was chosen as this approach rendered the surviving cells suitable for flow cytometric analy- sis. ...
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Role of cancer stem cells in breast and prostate cancer
... CSCs. Prostate and breast cancer cell lines cultured in 2D and 3D were treated with a novel withanolide derivative (LG-02) and Withanilode E to determine if these compounds were more effective at inducing ...
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Role of cancer stem cells in breast and prostate cancer
... of cancer largely depend on a succession of mutations and alterations within the genome to facilitate the progression of a neoplastic cell to a malignant tumour, although some may be triggered by non-mutational ...
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Stem cells in prostate cancer initiation and progression
... investigate prostate cancer initiation using mouse models of the ...tate cancer, disease in the Pten prostate-specific knockout mouse model progresses from PIN to invasive adenocarcinoma and ...
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MicroRNA Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development
... tumor-initiating cells (106), let-7 also exhibits tumor suppressive function in PCa ...modulating prostate tumor ...PCa cells compared to ...vs. prostate (Du145 and LAPC9) cancer ...
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Fibroblast Growth Factor Signaling in Prostate Stem Cells and Prostate Cancer
... for prostate cancer is on the rise. Prostate- specific antigen, or PSA, is a protein produced by cells of the prostate ...for prostate cancer, in conjunction with urine ...
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Wnt signalling in prostate cancer stem-like cells
... 77 et al., 2010). The microscope was set at x20 objective; zoom x1; 512x512. Gain was appropriately adjusted so as the signal would have scope to potentially increase or decrease in intensity before being saturated or ...
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Quantification of Mesenchymal Stem Cells (MSCs) at Sites of Human Prostate Cancer
... plastic-adhering cells characterized by the expression of CD90, CD73, and CD105 in the absence of hematopoietic markers, which can differentiate into osteoblasts, chondrocytes, and ...total cells present in ...
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TOP2A high is the phenotype of recurrence and metastasis whereas TOP2A neg cells represent cancer stem cells in prostate cancer
... words: prostate cancer, cancer stem cells, TOP2A, recurrence and metastasis Received: June 18, 2014 Accepted: August 28, 2014 Published: September 08, 2014 ABSTRACT Recurrence and ...
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Concise review: cancer cells, cancer stem cells, and mesenchymal stem cells: influence in cancer development
... breast cancer cells positive to ALDH by secretion of CXCR2 ligands inducing expression of Oct4 and ...breast cancer cells increase the release of TGFb1, VEGF, and PDGF-BB, which activate the ...
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Concise Review : Cancer Cells, Cancer Stem Cells, and Mesenchymal Stem Cells: Influence in Cancer Development
... ovarian cancer, the number of CSCs can be increased by MSCs iso- lated from human ovarian tumor ascites via BMP2 and BMP4 ...ovarian cancer cells with potential mediation in resist- ance to ...
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DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis
... in cells [13–15] ...in cancer cells [15,16] ...colorectal cancer cells in vivo [17,18] and in other cancer cells [19,20] ...3T3 cells but is highly induced at the G ...
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Cancer stem cells and angiogenesis
... of cells endowed with unique self-renewal capacity, tumorigenesis, and radio- and chemotherapy resistance, defined as cancer stem cells (CSCs) or tumor initiating ...These cells are ...
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