Protein Domain
Mutual information and variants for protein domain domain contact prediction
... ring protein-protein interactions across species based on sequence homology has a low level of accuracy, requir- ing a sequence identity of far higher than 70% ...previous protein-protein ...
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Role of Zika Virus Envelope Protein Domain III as a Target of Human Neutralizing Antibodies
... (WNV), and yellow fever virus (1, 2). Decades of research into the immune response that occurs following DENV infection revealed that neutralizing antibodies (Abs) targeting the envelope protein are a critical ...
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Protein domain evolution by comparative genomics
... complete domain combinations contains frequent tandem ly repeated ...identical domain types immediately following one another within a protein se ...repeated domain proteins are made up of ...
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A Tyr Residue in the Reverse Transcriptase Domain Can Mimic the Protein-Priming Tyr Residue in the Terminal Protein Domain of a Hepadnavirus P Protein
... P protein, but the presence of uni- versally conserved motifs (boxes 1/G and 2/F and boxes A to E; see ...P protein RT domain (3, ...P protein, our previous mutational analysis had strongly ...
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Bioinformatic Survey of S Layer Proteins in Bifidobacteria
... of protein secretion across cell membrane. S-layer (domain) protein needs such structural element to direct its ...(domain) protein have trans-membrane (TM) helices in both N-terminal ...
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IDDI: integrated domain-domain interaction and protein interaction analysis system
... includes protein, domain, PPI and DDI search system (see Figure ...in protein search, user can check the information of query protein such as protein function referring from Gene ...
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Phosphotyrosine recognition domains: the typical, the atypical and the versatile
... other protein domain families that can, at least with some of their members, also recognise pTyr residues in a sequence-specific ...HYB domain, the PKC δ and PKC θ C2 domains and RKIP, represents a ...
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Genetic Analysis of brahma: The Drosophila Homolog of the Yeast Chromatin Remodeling Factor SWI2/SNF2
... BRM protein with an ...BRM protein caused peripheral nervous system defects, homeotic transforma- tions, and decreased ...BRM protein is expressed at relatively high levels in nuclei throughout the ...
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Calculating the statistical significance of rare variants causal for Mendelian and complex disorders
... While there are gene-ranking methods based on other parameters [4], recently several gene-level ranking sys- tems have emerged based on measures for intolerance to mutations in the general population. The Residual Vari- ...
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Predictors of Treatment Adherence in Adolescents with Inflammatory Bowel Disease: The Role of Age, Body Satisfaction and Prospective Memory in Medication and Diet Behavior
... years, protein scientists have been accumulating data in an exponential ...analyze protein data in clear and efficient ways is becoming more and more ...genomics domain, there is no further research ...
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Support vector machines for predicting protein-protein interactions using domains and hydrophobicity features
... study protein-protein interactions to understand proteins ...of protein-protein interactions based on sequence information are becoming increasingly ...of protein-protein ...
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XIAP RING domain mediates miR-4295 expression and subsequently inhibiting p63 aprotein translation and promoting transformation of bladder epithelial cells
... a protein with three BIR domains and a RING- finger domain ...functional domain(s) responsible for XIAP regulation of human bladder carcinogenesis has not been ...RING domain specifically ...
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Sec-facilitated Protein Translocation and Membrane Integration
... nascent protein exists in either an off-state, in which nonbonding interactions between each residue and the rest of the system are excluded, or an on-state, in which all interactions are ...nascent protein ...
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S1 domain of the porcine epidemic diarrhea virus spike protein as a vaccine antigen
... All the animal experiments were performed in the ani- mal containment level 3 laboratories of VIDO-InterVac. All pigs were maintained and euthanized as per the protocol, approved by the University of Saskatchewan’s ...
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The PAS Domain Containing Protein HeuR Regulates Heme Uptake in Campylobacter jejuni
... IMPORTANCE Annually, Campylobacter jejuni causes millions of gastrointestinal infections in the United States, due primarily to its ability to reside within the gastrointestinal tracts of poultry, where it can be ...
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RiceAntherNet: a gene co expression network for identifying anther and pollen development genes
... OsCP1 (Oryza sativa Cysteine Protease1) encodes a cys- teine protease activated by TDR, which is required for tape- tum PCD (Lee et al., 2004; Li et al., 2006). A putative ortholog in Arabidopsis is reported for PCD ...
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Modified substrate specificity of a methyltransferase domain by protein insertion into an adenylation domain of the bassianolide synthetase
... A domain of BSLS is promiscuous and can activate both L-Leu and ...MT domain showed a preference for L- Phe-SNAC over L-Leu-SNAC ...A domain. Embedding the MT tunes the activity of the MT ...
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Identification of a membrane fusion domain and an oligomerization domain in the baculovirus GP64 envelope fusion protein.
... phobic amino acids. Amino acid substitutions that neutralized or altered the hydrophobicity of region I did not prevent oli- gomerization or surface localization of GP64 EFP but abol- ished acid-induced membrane fusion ...
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An Aptamer against the Matrix Binding Domain on the Hepatitis B Virus Capsid Impairs Virion Formation
... core protein lacking the 35 C-terminal arginine-rich amino acids, because this domain is dis- pensable for particle formation but able to bind unspecifically to nucleic acids ...binding domain and is ...
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Structural domains of the avian erythroblastosis virus erbB protein required for fibroblast transformation: dissection by in-frame insertional mutagenesis.
... In-frame insertions in the extracellular domain of the v-erbB protein, between the transmembrane domain and the kinase region, and in the extreme C terminus of this polypeptide did not a[r] ...
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