Protein–protein interactions (PPIs)
In silico study of SARS-CoV-2 Nucleocapsid Protein-Protein Interactions and Potential Candidates for their Stabilization
... non-native Protein-Protein Interactions (PPIs) of the nucleocapsid protein of MERS coronavirus is a valid strategy to inhibit viral replication, but no study up to date has been done in ...
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SIGNET: A Neural Network Architecture for Predicting Protein-Protein Interactions
... of protein-protein interactions (PPI) is critically important within the field of Molecular Biology, as proteins facilitate key organismal functions including the main- tenance of both cellular ...
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A bayesian kernel for the prediction of protein-protein interactions
... The Bayesian kernel was developed based on the Bayes’ Rule. The performance results of the Bayesian kernel outperformed most of the cited related work with ROC score of 0.8670. However, the comparison with some other ...
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Bioluminescence Resonance Energy Transfer System for Measuring Dynamic Protein Protein Interactions in Bacteria
... measuring interactions in pro- karyotic ...fluorescent protein (eYFP) ...rescent protein from Discosoma ...observed interactions between FlgM and FliA, two proteins in the flagellar regulon; ...
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DAPPER: a data-mining resource for protein-protein interactions
... DAPPER is content-rich and carefully curated with high-resolution experiments per- formed using affinity purifications followed by mass spectrometry. DAPPER is pre- sented through widely accepted and interoperable web ...
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Extracting Protein-Protein Interactions with Language Modelling
... In this paper we have presented and experimented several systems, that can be easily implemented, to extract directed Protein-Protein Interactions in bio-medical texts. We have shown that modeling ...
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Protein-protein interactions
... Protein-Protein Interactions: Chapter 1 ________________________________________ Introduction This is the phase problem in ...new protein structures, multiple isomorphous replacement (MIR) is ...
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Computational Design Of Protein–ligand And Protein–protein Interactions
... of protein-protein interactions allows for the potential development of symmetric assemblies of homomeric protein complexes with spherical shapes and hollow ...of protein cages for ...
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The interactome: Predicting the protein-protein interactions in cells
... of interactions that also contain the stable protein complexes ...on protein sequences, structures and their interactions are available ...confirmed protein-protein pairings ...
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Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)
... The main objective of this review is to present a detailed description of protein-protein interactions using photo- affinity labeling. In this review, we try to cover most of the recently developed ...
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Protein coadaptation and the design of novel approaches to identify protein protein interactions
... novel protein–protein interactions that are vital for the cell and the organism ...abundant interactions among nervous system CSS described to date, however, there is a vast number of orphan ...
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Prediction of crystal packing and biological protein-protein interactions with Linear Dimensionality Reduction-SVD
... In pattern recognition feature extraction is a special form of dimensionality reduction meth- ods. When the input features for a classification is too large to be processed and consists of redundant data then the input ...
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Computational redesign of protein-protein interactions
... Computational protein modeling predicts and manipulates the biophysical properties of proteins based on their amino acid ...Computational protein modeling has been applied to protein-protein ...
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Protein-protein interactions of transcription factor CREB 1
... CREB interactions appear to occur with nuclear factors only, that there is one or more strongly interacting factor(s) of approximately 97 kD in size which appears to be less abundant in D F9 cells than in UF9 ...
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A Meta-Heuristic Approach to Predict Protein-Protein Interaction Network
... functional organization of the cell. Understanding biological processes thus relies on a comprehensive knowledge of different types of protein–protein interactions (PPIs) and interaction ...
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The regulation of CFTR by protein-protein interactions
... Filamins are structural proteins which regulate cellular organization. Composed of two N-terminal actin binding domains and 24 Ig-like filamin repeats (the most C-terminal which mediates dimerization), filamin dimers are ...
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Integrated multifactor analysis explores core dysfunctional modules in autism spectrum disorder
... data, protein-protein interactions (PPIs), RNA-associated interactions and co-expression analysis, we first identified gene co-expression modules, observing that genes in these modules ...
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In silico prediction of protein protein interactions in human macrophages
... tissue-specific interactions; similarly, Rachlin and colleagues [27] provided networks dedicated to particular biological processes by con- textualizing them with Gene Ontology ...expression, protein ...
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Analysis and prediction of protein-protein interactions
... the protein interior (Lo Conte et a l, 1999; Janin & Chothia 1990), these atoms should be more constrained and restricted in their motion than those on the rest of the protein ...the protein to ...
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Protein-protein interactions in an alphavirus membrane.
... To further define protein interactions in the Sindbis virus membrane, we investigated the stability of the oligomers by exposing the virus to progressively increasing concentrations of T[r] ...
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