Protein S
High density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C
... final), protein S ...I protein adsorbed by the AI-11 MAB/Sepharose, 4%–15% gradi- ent SDS-PAGE was used to analyze 10 µl of each of the adsorbed ...fractions. Protein bands were stained with ...
10
Dissociation of activated protein C functions by elimination of protein S cofactor enhancement
... cofactor, protein S (27). Protein S may enhance APC anticoagulant activity by increasing its affinity for nega- tively charged phospholipid surfaces (27), re-positioning the APC active site ...
9
Inhibition of the anticoagulant activity of protein S by prothrombin
... of protein S overcame the inhibition by prothrombin and kinetic analysis of the interaction demonstrated that prothrombin acted as a competitive inhibitor to protein ...
7
Cleavage of protein S by a platelet membrane protease
... of protein S was associated with complete loss of cofactor anticoagulant ...that protein S binds to platelets and is inactivated by a novel Ca++-dependent membrane ...
7
Familial protein S deficiency is associated with recurrent thrombosis
... that protein C deficiency is associated with recurrent familial ...activated protein C functions as an ...plasma protein cofactor, referred to as protein ...activated protein C is ...
8
TAM receptor ligands in lupus: Protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus
... Samples from 107 SLE patients, participating in the Okla- homa Cohort for Rheumatic Disease, were studied. All patients satisfied at least four of the 1982 revised Ameri- can College of Rheumatology (ACR) criteria for ...
9
The Role of Protein C, Protein S, and Resistance to Activated Protein C in Legg-Perthes Disease
... of protein S deficiency were excluded from the ...the protein C and protein S assays from 4 cases and 3 controls was not obtained, and for the same reason, the APC-R assay was not done ...
8
Protein S as an in vivo cofactor to activated protein C in prevention of microarterial thrombosis in rabbits
... APC-protein S interaction, bovine APC expresses potent anticoagulant activity in rabbit plasma only when bovine protein S is also ...bovine protein S to the antithrombotic effect ...
8
Protein C and protein S deficiencies may be related to survival among hemodialysis patients
... [11]; however, the mechanism remains unclear. Throm- bosis involves various genetic and environmental factors [12, 13]. Under normal physiological conditions, the mechanism of coagulation control works in a multilevel ...
5
Anticoagulant Treatment With Rivaroxaban in Severe Protein S Deficiency
... severe protein S de fi ciency due to a homozygous mutation and recurrent episodes of skin necro- ...of protein C, other than severe protein S de fi ciency, outweighed the anticoagulant ef ...
7
Assessment of Protein C and Protein S of Pregnancy Loss Victims
... Those excluded from this study included subjects who were reactive to HIV 1 and II, HbsAg, HCV as well as smokers, patients with co-morbidities like hypertension, pelvic inflammatory disease, known thrombotic illness and ...
7
Enhancement of rabbit protein S anticoagulant cofactor activity in vivo by modulation of the protein S C4B binding protein interaction
... of protein S has been recently been observed to be involved in the interaction between protein S and C4b-binding protein (Walker, ...of protein S has been used to ...
9
Acquired deficiencies of protein S Protein S activity during oral anticoagulation, in liver disease, and in disseminated intravascular coagulation
... Protein S is a vitamin K-dependent plasma protein which serves as the cofactor for activated protein ...C. Protein S circulates in both an active, free form and in an inactive ...
11
Global, site-specific analysis of neuronal protein S-acylation
... protein sorting to lipid rafts. As well as allowing questions to be asked about the exact positioning of palmi- toylation sites, ssABE permitted the identification of peptides co-modified by both palmitoylation ...
14
The physiology of protein S-acylation
... also S-acylated but at a cysteine residue (C178) in the C-terminus that is more proximal than the cysteine residues of H- and N-RAS that are located adjacent to the prenylated –CAAX box ...(176). ...
91
Severe Protein S Deficiency in a Newborn
... Its therapy is similar to that for protein C deficiency with thrombotic episodes controlled by administration of plasma products containing the. missing protein[r] ...
5
Original Article Pathological features of mammary analogue secretory carcinoma of the salivary gland
... Mammaglobin protein, Gata3 protein, S-100 protein, DOG1 protein, and break-apart ETV6 fluorescence in situ hybridization (FISH) in forty salivary gland ...Mammaglobin protein, ...
6
Molecular genetics of palmitoyl protein thioesterase deficiency in the U S
... The current paper greatly expands the spectrum of PPT gene mutations, for a total of 21 to date. 19 different mutations were observed in our U.S. cohort, 14 of which have not been described previously. One nonsense ...
11
Oxidative stress and S-100B protein in children with bacterial meningitis
... A positive correlation was found between NO-index and CSF-WBCs. Another interesting result in this study is that the serum-NO level was higher in patients with gram pos- itive CSF culture compared to negative culture ...
9
3 Protein Structure-S
... Proteins accomplish many cellular tasks such as facilitating chemical reactions, providing structure, and carrying information from one cell to another. How a protein chain coils up and folds determines its ...
10