protein synthesis initiation factor 2
Regulation of protein synthesis in vesicular stomatitis virus-infected mouse L-929 cells by decreased protein synthesis initiation factor 2 activity.
... 3 0022-538X/82/030781-11$02.00/0 Regulation of Protein Synthesis in Vesicular Stomatitis VirusInfected Mouse L-929 Cells by Decreased Protein Synthesis Initiation Factor 2 Activity MICHA[r] ...
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A kinase able to phosphorylate exogenous protein synthesis initiation factor eIF-2 alpha is present in lysates of mengovirus-infected L cells.
... 3 0022-538X/86/121012-06$02.00/0 Copyright C 1986, American Society for Microbiology A Kinase Able To Phosphorylate Exogenous Protein Synthesis Initiation Factor eIF-2x Is Present in Lys[r] ...
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Eukaryotic Initiation Factor 4GII (eIF4GII), but Not eIF4GI, Cleavage Correlates with Inhibition of Host Cell Protein Synthesis after Human Rhinovirus Infection
... containing an extra sequence of 46 aa from the pBlueBacHis2 C baculovirus vector (Invitrogen) (16, 20). The ECL signal of the HeLa S10 corresponded to that elicited by 34 ng of eIF4GI. We calculated that eIF4GI ...
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Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2
... for protein synthesis ...(Figure 2) and Gcn2p (Dever et ...elongation factor eEF1A (previously eEF1␣), were pass eIF2B in vivo ...demonstrated factor, eEF1B, when provided on a ...
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Differential regulation of protein synthesis in skeletal muscle and liver of neonatal pigs by leucine through an mTORC1-dependent pathway
... of protein synthesis, and ribosomal protein S6 kinase 1 (S6K1) and eukaryotic initiation factor (eIF) 4E-binding protein-1 (4E-BP1) phosphorylation in gastrocnemius and masseter ...
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Double-stranded RNA-dependent protein kinase and 2-5A system are both activated in interferon-treated, encephalomyocarditis virus-infected HeLa cells.
... The extent of phosphorylation in the intact cell of the a-subunit of eucaryotic protein synthesis initiation factor eIF2 by the kinase was determined for the first time in this type of s[r] ...
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Herpes Simplex Virus 1 Infection Activates the Endoplasmic Reticulum Resident Kinase PERK and Mediates eIF-2α Dephosphorylation by the γ134.5 Protein
... dent protein kinase (PKR), which is a critical player of the interferon system ...translation initiation factor eIF-2 (eIF-2 ␣ ...exchange factor eIF-2B, thus seques- tering ...
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Protein Synthesis and Endoplasmic Reticulum Stress Can Be Modulated by the Hepatitis C Virus Envelope Protein E2 through the Eukaryotic Initiation Factor 2α Kinase PERK
... envelope protein, E2, is an endoplasmic reticulum (ER)-bound protein that contains a region of sequence homology with the double-stranded RNA-activated protein kinase PKR and its substrate, the ...
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Proteostatic Signaling & Control of Protein Synthesis
... ribosomal initiation complex subunit eIF2a (eukaryotic initiation factor 2 ...ribosomal initiation complex on mRNA resulting in attenuated rates of translation (~80% decrease) and ATP ...
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<p>eIF2α promotes vascular remodeling via autophagy in monocrotaline-induced pulmonary arterial hypertension rats</p>
... translation initiation factor 2, which is a key protein that catalyzes the initiation of protein ...translation initiation factor family, plays a key role in the ...
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Adenovirus virus-associated RNA and translation control.
... Translational control by adenovirus: lack of virus-associated RNA, during adenovirus infection results in phosphorylation of initiation factor eIF-2 and inhibition of protein synthesis..[r] ...
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Outgrowth of Bacillus cereus Spores Harboring Bacteriophage CP-51 DNA I. Initiation of Bacteriophage Development
... Initiation of Bacteriophage Development Received for publication 28 December 1972 Time of initiation of bacteriophage CP-51 RNA synthesis, inhibition of host DNA synthesis, initiation of[r] ...
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Presence of the cap-binding protein in initiation factor preparations from poliovirus-infected HeLa cells.
... 2 Presence of the Cap-Binding Protein in Initiation Factor Preparations from Poliovirus-Infected HeLa Cells JOANNA HANSEN' AND ELLIE EHRENFELD1 2* Departments of Cellular, Viral and Mole[r] ...
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Rifampin inhibition of bacteriophage phiX174 parental replicative-form DNA synthesis in an Escherichia coli dnaC mutant.
... DISCUSSION These data show that the host dnaC protein is required for OX174 parental RF DNA synthesis, presumably in the initiation of the synthesis of the complementary DNA strand, when[r] ...
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PubMedCentral-PMC4848592.pdf
... 200 protein coding regions ...near-cognate initiation codon drives translation from previously unrecognized ORFs, although the majority of the novel coding regions initiate with an AUG start ...a ...
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Human rhinovirus 14 infection of HeLa cells results in the proteolytic cleavage of the p220 cap-binding complex subunit and inactivates globin mRNA translation in vitro.
... The effect of p220 cleavage correlates with the inhibition of cellular protein synthesis by poliovirus or HRV-14 infection and with the inability of the initiation factors to function on[r] ...
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Association of cap-binding protein with eucaryotic initiation factor 3 in initiation factor preparations from uninfected and poliovirus-infected HeLa cells.
... 1982, p, 200-207 0022-538X/82/040200-08$02.00/0 Association of Cap-Binding Protein with Eucaryotic Initiation Factor 3 in Initiation Factor Preparations from Uninfected and Poliovirus-In[r] ...
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Effect of Pactamycin on Synthesis of Poliovirus Proteins: a Method for Genetic Mapping
... In uninfected HeLa cells, at 10-7 M pactamycin, the time course of breakdown of polyribosomes paralleled the inhibition of protein synthesis, suggesting that initiation of protein synthe[r] ...
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The IE180 Protein of Pseudorabies Virus Suppresses Phosphorylation of Translation Initiation Factor eIF2α
... translation initiation factor eIF2 ␣ ...viral protein(s) is required for interference with eIF2␣ phos- ...within 2 h after PRV inocu- lation. PRV encodes only one immediate-early ...
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A Dominant Mutation in the Chlamydomonas reinhardtii Nuclear Gene SIM30 Suppresses Translational Defects Caused by Initiation Codon Mutations in Chloroplast Genes
... would not be surprising if SIM30 encodes a ribosomal protein o r initiation factor.. proportion to the basal level for each initiation codon mutant tested, it probab[r] ...
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