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Proteins with multiple roles

Multiple roles of the cytoskeleton in autophagy

Multiple roles of the cytoskeleton in autophagy

... has multiple roles in the regulation of the actin ...monomer-binding proteins inhibit poly- merization by sequestering away free actin subunits, whereas others stimulate the same process by ...

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The multiple roles of histidine in protein interactions

The multiple roles of histidine in protein interactions

... The calculated values of PCM may be not very accurate, but the qualitative order is meaningful. In aqueous solu- tion the cation-π interactions between protonated amino acids and aromatic amino acids may be more ...

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The Multiple Roles of Waters in Protein Solvation

The Multiple Roles of Waters in Protein Solvation

... Finally, to complete our study we analyzed the solvent environment in one of the few proteins for which the unfolded ensemble has been characterized by a combination of NMR and MD simulations: Ubiquitin 28 . We ...

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Multiple Roles of Mitochondria in Aging Processes

Multiple Roles of Mitochondria in Aging Processes

... initiate multiple processes leading to age-associated deterioration of the cellular functions and become targets of reactions leading to increased ROS generation, mtDNA mutations, oxidation of mitochondrial ...

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Multiple roles and effects of a novel Trichoderma hydrophobin

Multiple roles and effects of a novel Trichoderma hydrophobin

... The direct antifungal activity of HYTLO1 seems to be a peculiar characteristic of this hydrophobin produced by T. longi- brachiatum, because similar proteins isolated, for instance, from two strains of T. ...

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The multiple roles of sucrase-isomaltase in the intestinal physiology

The multiple roles of sucrase-isomaltase in the intestinal physiology

... gene leading to single amino acid exchanges in the pro- tein. These mutations can affect each of the SI domains but do not per se lead to complete lack of SI or its ac- tivities in the BBM essentially. Requirements for ...

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Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles

Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles

... Yeast Atg8 and its homologs are involved in autophagosome biogenesis in all eukaryotes. These are the most widely used markers for autophagy thanks to the association of their lipidated forms with autophagic membranes. ...

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Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles

Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles

... during autophagy. The Atg8 protein is bound to the phagophore through lipidation of its C-terminal glycine residue. This process is mediated by a complex that is analogous with the ubiquitylation complex as the Atg8 ...

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Emerging roles for HOX proteins in synaptogenesis

Emerging roles for HOX proteins in synaptogenesis

... project onto the brainstem cochlear nuclear complex. Tonotopic organization is maintained at the different relays of the auditory pathway, in brainstem cochlear nuclei, midbrain, thalamus, and cortex (Kandler et al., ...

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Roles of neuro-exocytotic proteins at the neuromuscular junction

Roles of neuro-exocytotic proteins at the neuromuscular junction

... or multiple isoforms of α-neurexin is ...modulatory roles, Munc18-1 might be a presynaptic target of the retrograde signals involved in transsynaptic homeostatic upregulation of transmitter release ...

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Heat shock proteins in multiple myeloma

Heat shock proteins in multiple myeloma

... these proteins in ...shock proteins are still not fully understood, with multiple isoforms of the same heat shock protein playing distinct or compensatory ...the roles of individual heat shock ...

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Understanding the physiological roles of the neuronal calcium sensor proteins

Understanding the physiological roles of the neuronal calcium sensor proteins

... why multiple GCAPs are required for light ...of multiple GCAPs appears to be related to a need for sensors with differing Ca 2+ sensitivities to allow responses to occur over a wide range of Ca 2+ ...

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Peroxisome membrane proteins: Multiple trafficking routes and multiple functions?

Peroxisome membrane proteins: Multiple trafficking routes and multiple functions?

... The multiple functions of Pex19p raise the question of how the roles of this protein relate to its structural ...with multiple PMPs, including Pex3, 11, 12, 13, 16 and 26 and various transporters ...

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Complementary Roles of Multiple Nuclear Targeting Signals in the Capsid Proteins of the Parvovirus Minute Virus of Mice during Assembly and Onset of Infection

Complementary Roles of Multiple Nuclear Targeting Signals in the Capsid Proteins of the Parvovirus Minute Virus of Mice during Assembly and Onset of Infection

... two proteins (VP1, 82 kDa; VP2, 63 kDa) forming the T ⴝ 1 icosahedral capsid of the parvovirus minute virus of mice (MVM) and their functions in viral biogenesis and the onset of ...VP1 proteins mutated at ...

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Developing roles for Hox proteins in hindbrain gene regulatory networks

Developing roles for Hox proteins in hindbrain gene regulatory networks

... The r4 regulatory network is very robust From the previous discussion it emerges that hoxb1b and RA are jointly required for r4 formation, while multiple factors (at least hnf1ba, MafB/valentino, egr2/krox20, RA ...

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The Roles of Moonlighting Proteins in Bacteria

The Roles of Moonlighting Proteins in Bacteria

... of proteins in bacteria are adhesion to host epithelia, host components, such as extracellular matrices (ECMs) and plasminogen, and the modulation of host immune ...moonlighting proteins share functional ...

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The Multiple Roles of Medicaid

The Multiple Roles of Medicaid

... Muskie School of Public Service Performance & Quality Utilization Management Financial Management Systems Change Payment Models Collaboration Stakeholder Engagement Social Se[r] ...

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Nuclear roles for cilia-associated proteins

Nuclear roles for cilia-associated proteins

... ciliogenesis‑associated proteins are found within nuclei where they play roles in the regulation of gene expression, DNA repair, and nuclear import and ...

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Structural Roles of Polyoma Virus Proteins

Structural Roles of Polyoma Virus Proteins

... The superhelical, closed circular form of polyoma deoxyribonucleic acid (DNA) (Co 1) is bound in a 25S DNA-protein complex to the viral histone-like proteins after alkaline disruption of[r] ...

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Multiple Roles of Adult Learners

Multiple Roles of Adult Learners

... Common Problems Once adults have made the decision to enter higher education, threats to success caused by multiple role demands and institutional barriers form a web of perception, constraint, and role demands. ...

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