Protoporphyrin IX (PpIX)
Carbon dot-protoporphyrin IX conjugates for improved drug delivery and bioimaging
... as protoporphyrin IX (PpIX) to tar- get tumours via the release of toxic singlet oxygen when ...improve PpIX cellular uptake and ...to PpIX. PpIX-containing CDs showed a ...
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Light harvesting in silicon(111) surfaces using covalently attached protoporphyrin IX dyes
... paper, Protoporphyrin IX was chosen due to the commercial availability, ease of functionalisation and shifting of the absorption and emission maxima by coordination with metal ...a PpIX molecule ...
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Apoptosis of THP-1 macrophages induced by protoporphyrin IX-mediated sonodynamic therapy
... sonosensitizer, protoporphyrin IX (PpIX), had been ...of PpIX- mediated SDT on macrophages, which are the main culprit in progression of ...with PpIX. Fluorescence microscopy showed ...
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Enhancement of Cancer-Specific Protoporphyrin IX Fluorescence by Targeting Oncogenic Ras/MEK Pathway
... to protoporphyrin IX (PpIX), an endogenous fluoropho- re that exhibits red fluorescence (630 nm) under blue light (405 nm) excitation ...[7]. PpIX can be preferential- lly accumulated in ...
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Modelling topical photodynamic therapy treatment including the continuous production of Protoporphyrin IX
... molecule, Protoporphyrin IX ...of PpIX, especially after short incubation times, prior to light ...the PpIX distribution depends on the incubation time and the treatment modality is ...the ...
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Light harvesting in silicon(111) surfaces using covalently attached protoporphyrin IX dyes
... of protoporphyrin IX attachment on the silicon ...the PpIX terminated silicon surface with a 1,4 butanediol linker is shown in ...the PpIX molecules were attached on the surface in accordance ...
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A quantitative study of in vivo protoporphyrin IX fluorescence build up during occlusive treatment phases
... molecule protoporphyrin IX (PpIX) is activated, resulting in the production of sin- glet oxygen, which subsequently leads to cell ...death. PpIX is metabolised from a topically applied ...
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In-vivo kinetics of inhaled 5-Aminolevulinic acid-Induced Protoporphyrin IX fluorescence in bronchial tissue
... The detection of premalignant and early-malignant endo- bronchial alterations is growing increasingly important in the diagnosis of lung cancer, since an acceptable progno- sis is strictly confined to the early stage of ...
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μ Oxo bis[(protoporphyrin IX dimethyl ester)iron(III)]
... The -oxo dimer of iron protoporphyrin IX (FePPIX) is relevant in biology. For example, the black pigment of Porphyromonas gingivalis, a principal agent in adult perio- dontitis, has been identi®ed as the ...
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Zinc Protoporphyrin IX Binds Heme Crystals to Inhibit the Process of Crystallization in Plasmodium falciparum
... zinc protoporphyrin IX, normally present at ...zinc protoporphyrin IX inhibition of heme crystallization similar to the antimalarial ...Zinc protoporphyrin IX neither forms ...
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Protoporphyrin IX photobleaching of subcellular distributed sites of leukemic HL60 cells based on ALA PDT in vitro
... induced Protoporphyrin IX photobleaching exhi- bited a complex series of photophysical and photoche- mical reactions and the bleaching kinetics are much more complicated ...the Protoporphyrin ...
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Klein, Susanne (2005): Einfluss verschiedener Faktoren auf die durch 5-Aminolävulinsäure und ihre Ester induzierte Protoporphyrin IX - Fluoreszenz in Zervixkarzinomzelllinien. Dissertation, LMU München: Medizinische Fakultät
... Der PpIX-Anstieg resultiert aber nicht nur daraus, dass PpIX nicht weiter zu Häm umgewandelt wird, sondern auch daraus, dass die negative Rückkopplung der nun in geringerer Menge gebildeten Hämmoleküle auf ...
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Development of a handheld fluorescence imaging device to investigate the characteristics of protoporphyrin IX fluorescence in healthy and diseased skin
... on PpIX accumulation during three hours of incubation from the application of the pro-drugs and discuss the limitations and clinical relevance of PpIX fluorescence ...studying PpIX formation in NMSC ...
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Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells
... Recently, a detailed analysis of the oligomeric state of TAp73 alpha by Melino’s and Dötsch’s labs revealed a high structure homology between p53 and p73 tetram- ers [29]. The study thus implies that p73 can be phar- ...
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Factors affecting amninolaevulinic acid-induced generation of protoporphyrin IX
... The aims of this study are: 1 to investigate whether there is production and accumulation of PPIX by vascular endothelial and smooth muscle cells on exposure to ALA and whether this lead[r] ...
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Action of protoporphyrin IX (PP IX) in the lifespan of Drosophila melanogaster deficient in endogenous antioxidants, Sod and Cat
... According to the effect of PP-IX on both the wild type CS and the Cat strain, we suggest three possible mechanisms of action: a as inductor of the antioxidant enzymes to achieve normal l[r] ...
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Synthetic Porphyrinic Macrocycles for Photodynamic Therapy and Other Biological Applications
... Protoporphyrin IX and its metal derivatives have been used as photosensitizers in photodynamic therapy (PDT) for the treatment of ...cancer. PPIX after penetration into human red blood cells can ...
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In Vitro Culture of Shell Gland Epithelial Cells in Japanese Quail (Coturnix coturnix japonica)
... of protoporphyrin IX (PpIX), superficial eggshell pigment, from shell gland cells of Japanese quail, the epithelial cells of the gland were collected and isolated for cultivation in vitro ...for ...
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Intermolecular Bonding of Hemin in Solution and in Solid State Probed by N K-edge X-ray Spectroscopies
... iron protoporphyrin IX chloride (FePPIX-Cl, or hemin, Figure 1a) forms monomer species when dissolved in dimethyl sulfoxide (DMSO), while dimer structures are present in aqueous ...
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Inhibition of Hepadnavirus Reverse Transcriptase-ε RNA Interaction by Porphyrin Compounds
... Hemin is a cyclic compound formed by the linkage of four pyrrole rings with a central iron ion (Fig. 1). We excluded the requirement for iron by demonstrating that two iron-free he- min analogs, protoporphyrin ...
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