Pulmonary microvascular endothelial cells
miR-34a is involved in CSE-induced apoptosis of human pulmonary microvascular endothelial cells by targeting Notch-1 receptor protein
... human pulmonary microvascular endothelial cells (HPMEC), miR-34a expression was sig- nificantly increased ...malignant cells by directly targeting mRNA [16, ...as endothelial ...
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adrenoceptor protects human pulmonary microvascular endothelial cells from TNF-α induced hyper-permeability
... human pulmonary microvascular endothelial cells (HPMECs) upon TNF-α-induced endothelial dysfunction, including apoptosis, hyperpermeability, and increased leukocyte ...induced ...
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VEGF isoforms have differential effects on permeability of human pulmonary microvascular endothelial cells
... EC: Endothelial cell; ECIS: Electrical cell impedance system; eNOS: Endothelial nitric oxide synthase; EVOM: Epithelial voltohmmeter; FITC: Fluorescein isothiocyanate; HPMEC: Human pulmonary ...
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Isolation and characterisation of human pulmonary microvascular endothelial cells from patients with severe emphysema
... of cells to injury, thus limiting their relevance ...monary microvascular endothelial cells, which form the luminal barrier of intra-acinar arterioles and venules and the alveolar capillary ...
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Hyperoxic sheep pulmonary microvascular endothelial cells generate free radicals via mitochondrial electron transport
... suggesting that the observed radicals were derived from O2-.. Studies with deferoxamine suggested that the generation of .R occurred secondary to the formation of .OH from O2-. via an iron-mediated Fenton reaction. ...
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Original Article Lipopolysaccharides increase Kir2.1 expression in lung endothelial cells
... Pulmonary microvascular endothelial cells were grown on poly-L-lysine-coated coverslips in serum-free DMEM, for 24 hours at 37°C, in an incubator with 5% CO 2 ...Then, pulmonary micro- ...
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Annexin A1 protein regulates the expression of PMVEC cytoskeletal proteins in CBDL rat serum induced pulmonary microvascular remodeling
... of pulmonary microvascular endothelial cells (PMVECs) in IPVD of HPS; the change in cytoskeletal proteins and their molecular mechanism play an essential role in the proliferation, phenotype ...
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Lipopolysaccharide-induced caveolin-1 phosphorylation-dependent increase in transcellular permeability precedes the increase in paracellular permeability
... in endothelial cells; however, the mechanisms regarding this response and the con- sequences on caveolae-mediated transcellular transport have not been completely ...in pulmonary microvascular ...
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Dexmedetomidine attenuates lung apoptosis induced by renal ischemia–reperfusion injury through α2AR/PI3K/Akt pathway
... mice pulmonary microvascular endothelial cells were treated with serum from mice obtained following sham or ...in cells, alone or with atipamezole or ...
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Extracellular Superoxide Dismutase Overexpression Can Reverse the Course of Hypoxia-Induced Pulmonary Hypertension
... of pulmonary hypertension ...using pulmonary microvascular endothelial cells showed that cells transfected with EC-SOD had signifi- cantly less accumulation of xanthine oxidase ...
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Role of iNOS in septic pulmonary microvascular endothelial cell activation
... iNOS plays an important role in disrupting cellular junctional proteins. As mentioned earlier that disrupted F actin formation has potentiated LPS induced iNOS expression. Moreover, iNOS induction followed by cytokines ...
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Prostaglandin D 2strengthens human endothelial
... barrier disruption in primary human pulmonary and dermal microvascular endothelial cells as well 85.. as in pulmonary artery endothelial cells by activating EP4 and only to a small exte[r] ...
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Hypoxia Induces Permeability and Giant Cell Responses of Andes Virus-Infected Pulmonary Endothelial Cells by Activating the mTOR-S6K Signaling Pathway
... hantavirus pulmonary syndrome (HPS) charac- terized by hypoxia, thrombocytopenia, and vascular leakage leading to acute pulmonary ...nary microvascular and lymphatic endothelial cells ...
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Stickel, Diana (2017): Cytosolic and mitochondrial Ca2+ handling in pulmonary arterial smooth muscle and endothelial cells. Dissertation, LMU München: Medizinische Fakultät
... the endothelial layer can be analyzed using the Electrical Cell-Substrate Impedance Sensing ...the endothelial barrier function has been in- vestigated by Shinde et ...vein endothelial cells ...
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Effects of Lipopolysaccharide and Mannheimia haemolytica Leukotoxin on Bovine Lung Microvascular Endothelial Cells and Alveolar Epithelial Cells
... bovine pulmonary epithelial (BPE) cell and bovine lung microvascular endothelial cell monolayer permeability, as measured by trans-well endothelial and epithelial cell electrical resistance ...
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The Metalloproteinase-Dependent Role of TIMPs in Regulation of Pulmonary Microvascular Endothelial Cell Barrier Function During Sepsis
... maintaining pulmonary microvascular barrier function following septic lung injury, murine PMVEC were isolated from the lungs of healthy male WT and Timp3 -/- mice and cultured for use in all in vitro ...
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Purine Transport and Metabolism in Microvascular Endothelial Cells
... vein endothelial cells showed that PKC inhibition led to increased nitric oxide (NO) production (40), perhaps a similar mechanism occurs in MVECs and is responsible for the [ 3 H]hypoxanthine uptake ...
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A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier
... BBB microvascular endothelial cells and to apply this model to the study of RNA ...brain microvascular endothelial cells (HBMEC) (9), an immortalized human BBB ...
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Ebola Virus Glycoprotein: Proteolytic Processing, Acylation, Cell Tropism, and Detection of Neutralizing Antibodies
... other cells (30); however, the cells normally used for in vitro propagation of filoviruses ...kidney cells such as Vero cells) were not included in the test ...human endothelial ...
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ENT1 and ENT1 mice during both normoxic and hypoxic conditions. Gene expression was
... Another hypoxia induced factor is nitric oxide (NO) which is the active moiety of the endothelium-derived relaxing factor (EDRF) [40]. As a key regulator of vascular homeostasis, under basal conditions, low levels of NO ...
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