PYRAZOLE DERIVATIVES
A short review of some pyrazole derivatives and their applications
... One of the major concerns is to exhibit simple routes for the synthesis of pyrazole derivatives. The other important area of research in synthetic organic chemistry is “Green Chemistry’’. The Green ...
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SYNTHESIS AND SPECTRAL ANALYSIS OF SOME PYRAZOLE DERIVATIVES
... Synthetic pyrazole derivatives (5a-f) have been synthesized using conventional method producing good yield in ethanol with hydrazine in presence of ...(4a-f) derivatives these synthesized compounds ...
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Synthesis, Characterization and Biological evaluation of substituted Pyrazole derivatives
... substituted pyrazole derivatives. Pyrazole derivatives have been shown to have wide variety of pharmacological activities like antimicrobial, antiviral, antihistaminic, antitumor, antipyretic, ...
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Synthesis, characterization and biological activity of certain Pyrazole derivatives
... The present study describes the synthesis, characterization and antibacterial evaluation of certain pyrazole derivatives 3a – 3g. Assignment of selected characteristic IR bands[16,17] provides significant ...
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MICROWAVE ASSISTED SYNTHESIS OF INDOLE BASED 4 DIMETHYLAMINO PHENYL N METHYL/PHENYL PYRAZOLIDINE PYRAZOLE DERIVATIVES AND STUDY OF THEIR ANTIINFLAMMATORY ACTIVITY
... 3-methyl-5-phenylpyrazolesulfonylurea derivatives and studied their antidiabetic activity while synthesis of some new pyrazoles and triazoles bearing a 6,8- dibromo-2-methylquinazoline moiety and their analgesic ...
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SYNTHESIS, IN VITRO ANTIBACTERIAL ACTIVITY AND DOCKING STUDIES OF NEWER PYRAZOLE DERIVATIVES
... In summary, we have developed and synthesized efficient newer pyrazole derivatives for use in antibacterial activity. The present synthetic protocols should, in principle, be applicable in synthesizing ...
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In vitro Anti Leukemia Cancer Activity of Some Novel Pyrazole Derivatives and Pyrazoles Containing Thiazole Moiety
... novel pyrazole derivatives (2, 5, 6 and 7) and pyrazole derivatives (3 and 4) containing thiazole moiety via by ethyl β-(p-chlorophenyl)–α-cyanoacrylate (1) and thiosemicarbazide as starting ...
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SYNTHESIS, CHARACTERIZATION, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SOME SUBSTITUTED PYRAZOLE DERIVATIVES
... INTRODUCTION: Pyrazole derivatives have attracted the attention of research scholars on account of their wide range of applications in ...that pyrazole is used directly in the synthesis of the amino ...
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SYNTHESIS OF PYRAZOLE DERIVATIVES AND THEIR ANTIMICROBIAL ACTIVITIES
... term Pyrazole was given by Ludwig Knorr in ...natural pyrazole, 1-pyrazolyl-alanine, was isolated from seeds of ...watermelons. Pyrazole is a five member heterocyclic ring which is a multipurpose ...
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SYNTHESIS, CHARACTERIZATION, AND BIOLOGICAL EVALUATION OF PYRAZOLE DERIVATIVES
... novel pyrazole derivatives as possible antimicrobial ...trisubstituted pyrazole derivatives have been synthesized by the reaction of substituted chalconeswith hydrazine ...
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FACILE SYNTHESIS AND ANTIMICROBIAL SCREENING OF PYRAZOLE DERIVATIVES
... containing pyrazole derivatives have been synthesized from base catalyzed reaction between N-acetyl-3-4-diphenylpyrazole and substituted benzaldehydes by grinding technique afforded 1-benzoaceto-3-5- ...
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GREENER APPROACH OF SYNTHESIS OF AZO DERIVATIVES AND BIS PYRAZOLE DERIVATIVES ALONG WITH ANTIMICROBIAL SCREENING
... Azo derivatives 7a-f and bis-pyrazole derivatives 13a-f were screened for their antibacterial activity against gram positive bacteria Staphylococcus aureus (NCIM 2079), Bacillus subtilis (NCIM 2250) ...
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Synthetic and Medicinal Importance of Pyrazole Derivatives
... its derivatives play an important role in synthetic as well as medicinal chemistry as these constitute the framework of numerous drugs, dyes and hence prompted the organic chemist to evolve several synthetic ...
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SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SOME NEW PYRAZOLE DERIVATIVES
... test pyrazole derivatives given by oral route at 50mg/kg did not significantly alter the reestablishment time; all animals performed normal reestablishment immediately ...
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Coordination chemistry of pyrazole derivatives
... Azole is the suffix used for five-membered ring containing two or more hetero-atoms, at least one of which is nitrogen for example pyrazoles and pyrazole derivatives such as 5- pyrazalones which were formed ...
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Synthesis and Antimicrobial Activity of Novel Pyrazole Derivatives
... its derivatives in ethanol in the presence of piperidine as a catalyst under reflux via elimination of water was afforded the corresponding [(5-chloro-3-methyl- 1-phenyl-1H-pyrazol-4-yl)methylene]-2-imino-2H- ...
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Synthesis and antimicrobial activities of some new pyrazole derivatives
... pyrazoline derivatives have been synthesised by the condensation of pyrazoline derivatives (obtained by the reaction of various chalcones with hydrazine hydrate) with chloroacetyl chloride and glacial ...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NEW PYRAZOLE DERIVATIVES
... INTRODUCTION: Pyrazole symbolizes a class of simple aromatic ring organic compounds of the heterocyclic series which is a 5-membered ring skeleton composed of three carbon and two nitrogen ...term pyrazole ...
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In silico predictive for modification of chalcone with pyrazole derivatives as a novel therapeutic compound for targeted breast cancer treatment
... Both synthesis and natural products chalcones have been proven in the various studies for important pathway or molecular targets in cancers. Chalcone has the advantages of being inexpensive, easily available, and less ...
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Synthesis Of Novel Pyrazole Derivatives Of Chalcones
... chalcone derivatives exhibit diverse pharmacological activities, such as potential Cytotoxic agents, antimicrobial agents, antiviral, anti-inflammatory, anesthetic, ...heterocyclic derivatives of chalcone ...
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