Pyrrolidine dithiocarbamate
Antiviral Effects of Pyrrolidine Dithiocarbamate on Human Rhinoviruses
... Human rhinoviruses (HRVs) are the predominant cause of the common cold. The frequency of HRV infections in industrial countries and the lack of effective therapeutical treatment underline the importance of research for ...
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SYNTHESIS, CHARECTERISATION AND ANTIBACTERIAL STUDIES OF COPPER(II) MIXED-LIGAND COMPLEXES OF PYRROLIDINE DITHIOCARBAMATE AND SCHIFF BASE
... Schiff Base and the mixed ligand complexes of copper- pyrrolidine dithiocarbamate were analysed. All the complexes were stable in air and soluble in DMF, DMSO and insoluble in acetone, chloroform, and ...
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Pyrrolidine Dithiocarbamate Alleviated Anxiety in Diabetic Mice
... of pyrrolidine dithiocarbamate on anxiety of streptozotocin-induced diabetic mouse using the open field and the elevated plus maze ...with pyrrolidine dithiocarbamate or ...After ...
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Pyrrolidine Dithiocarbamate Inhibits Herpes Simplex Virus 1 and 2 Replication, and Its Activity May Be Mediated through Dysregulation of the Ubiquitin-Proteasome System
... Pyrrolidine dithiocarbamate (PDTC), a stable pyrrolidine de- rivative of dithiocarbamates, is well suited for modifying the in- tracellular redox status of a given gene under defined tissue culture ...
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Extraction of Trace Copper(II) in Water Samples using Ammonium Pyrrolidine Dithiocarbamate(APDC) Modified Carbon Nanotubes to Measurement by FAAS
... Fig.1. show the morphology and size of Multi walled carbon nanotubes (MWCNTs) modified by Ammonium Pyrrolidine Dithiocarbamate(APDC) sorbent as shown in Fig. 1. sorbent retained a homogenous distribution in ...
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Short-term pyrrolidine dithiocarbamate administration attenuates cachexia-induced alterations to muscle and liver in Apc Min/+ mice
... tissues. Pyrrolidine dithiocarbamate (PDTC) is a thiol compound having anti-inflammatory and antioxidant properties which can inhibit STAT3 and nuclear factor κB (NF-κB) signaling in ...
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Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells
... and pyrrolidine dithiocarbamate (PDTC), a known copper- binding compound and antioxidant, can interact with copper to form cancer-specific proteasome inhibitors and apoptosis inducers in human breast cancer ...
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Therapeutic effects of pyrrolidine dithiocarbamate on acute lung injury in rabbits
... The present study is aimed at evaluating the effects of pyrrolidine dithiocarbamate PDTC, an inhibitor of NFB, on alveolar-capillary barrier dysfunction, lung tissue edema and compromise[r] ...
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Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes
... Pyrrolidine dithiocarbamate (PDTC) is a blood-brain barrier permeant metal-chelating compound possessing antioxidant and anti-inflammatory properties. Many studies have reported induction of endogenous ...
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Inhibition of Polyprotein Processing and RNA Replication of Human Rhinovirus by Pyrrolidine Dithiocarbamate Involves Metal Ions
... Pyrrolidine dithiocarbamate (PDTC) is an antiviral compound that was shown to inhibit the replication of human rhinoviruses (HRVs), poliovirus, and influenza ...
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An experimental study on effects of pyrrolidine dithiocarbamate on ischemia reperfusion injury in testis
... Pyrrolidine dithiocarbamate is a low-molecular weight thiol compound used as an antioxidant against the toxic impacts of free radicals. This beneficial effect of PDTC is linked with its thiol group, which ...
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Pyrrolidine Dithiocarbamate (PDTC) Attenuates Luteolin Induced Apoptosis in Human Leukemia HL 60 Cells
... Studies have indicated that flavonoid luteolin is a potential inhibitor of tumor cell proliferation and may function as an anticarcinogenic agent. Pyrrolidine dithiocarbamate (PDTC), a synthetic compound, ...
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Pyrrolidine Dithiocarbamate Reduces Coxsackievirus B3 Replication through Inhibition of the Ubiquitin-Proteasome Pathway
... Coxsackievirus B3 (CVB3) is one of the most common pathogens for viral myocarditis. The lack of effective therapeutics for CVB3-caused viral diseases underscores the importance of searching for antiviral compounds. ...
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Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-κB activity in autosomal dominant polycystic kidney disease cells
... Methods: Immortalized autosomal dominant PKD (ADPKD) cells that are heterozygous (WT9-7) and homozygous (WT-9-12) for a truncating Pkd1 mutation, and immortalized normal human tubular ce[r] ...
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Crystal structure of 1 [(4 methylbenzene)sulfonyl]pyrrolidine
... The title compound was prepared by the dropwise addition of p-toluenesulfonyl chloride (1.00 g, 5.25 mmol) to a stirring mixture of pyrrolidine (0.48 ml, 5.90 mmol) and 10 ml of tetrahydrofuran. This was followed ...
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Electrochemical Sensor for the Determination of Hydrazine Using MWCNT/Dopamine Dithiocarbamate Modified Electrode
... carcinogenic hydrazine has been reported [9]. From our laboratory also we have reported CMEs for the determination of Hydrazine. Nickel hexacynoferrate modified electrode was used for hydrazine determination [21]. ...
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Triphenyl(pyrrolidine 1 carbodithioato κS)tin(IV)
... intramolecular Sn S contact [3.0270 (9) A ˚ ] occurs and two intramolecular C—H S interactions help to establish the conformation. Three of the methylene groups of the pyrrolidine-1-carbodithioate ligand are ...
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Spectrochemical Investigation of di methoxy Aniline Dithiocarbamate metal complexes-Biological activity
... 0.05 mol of amine was dissolved in 30 ml of absolute alcohol in a clean beaker which was placed in ice bath. To this cold solution add 5 ml of Sodium hydroxide (10N) solution, and then add Pure carbon disulphide (0.05ml) ...
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1 [(2 Naphthylsulfonyl)oxy]pyrrolidine 2,5 dione
... organic papers Data collection: CrysAlisCCD Oxford Diffraction, 2003; cell refinement: CrysAlisRED Oxford Diffraction, 2003; data reduction: CrysAlisRED; programs used to solve structure[r] ...
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1 Phenyl 4 (triphenylphosphanylidene)pyrrolidine 2,3,5 trione
... Data collection: CAD-4 Software Enraf–Nonius, 1989; cell refinement: CAD-4 Software; data reduction: XCAD4 Harms & Wocadlo, 1995; programs used to solve structure: SHELXTL Sheldrick, 200[r] ...
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