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randomized controlled trials (RCTs)

Randomized controlled trials – a matter of design

Randomized controlled trials – a matter of design

... Abstract: Randomized controlled trials (RCTs) are the hallmark of evidence-based medicine and form the basis for translating research data into clinical ...clinical trials using the databases ...

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A Meta-analysis of Randomized Controlled Trials. Review

A Meta-analysis of Randomized Controlled Trials. Review

... Several randomized controlled trials (RCTs) have com- pared the combination of LET and ACLR with isolated ACLR, 1,4,8,18,19,45,46,51 but many of these trials contained relatively small cohorts ...

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The quality of reporting of randomized controlled trials of electroacupuncture for stroke

The quality of reporting of randomized controlled trials of electroacupuncture for stroke

... high-quality randomized controlled trials (RCTs) and RCT itself, especially those with double-blind placebo controls, are commonly regarded the highest level of evidence in judging the treatment ...

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Randomized controlled trials of malaria intervention trials in Africa, 1948 to 2007: a descriptive analysis

Randomized controlled trials of malaria intervention trials in Africa, 1948 to 2007: a descriptive analysis

... Africa. Randomized controlled trials (RCTs) are universally considered the best study type to rigorously assess whether an intervention is ...

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A systematic appraisal of allegiance effect in randomized controlled trials of psychotherapy

A systematic appraisal of allegiance effect in randomized controlled trials of psychotherapy

... Conclusions In this study, we show that experimenter’s allegiance effect inflates the reported effect sizes in randomized controlled trials in psychotherapy by 30 %. This treat- ment effect could be ...

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Twins as Participants in Randomized Controlled Trials: A Review of Published Literature

Twins as Participants in Randomized Controlled Trials: A Review of Published Literature

... PRISMA diagram to illustrate the literature search process and the resulting number of reviewed articles found in the Medline, Psych INFO and EMBASE databases. Zygosity and twin assignment across the randomized ...

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Methodological review: quality of randomized controlled trials in health literacy

Methodological review: quality of randomized controlled trials in health literacy

... improvement in actual patient health). Ioannidis [50] concluded that too many RCTs are problematic in exe- cution, stating that many “…simply represent wasted effort because the questions they ask and the comparisons and ...

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Inadequate description of educational interventions in ongoing randomized controlled trials

Inadequate description of educational interventions in ongoing randomized controlled trials

... clinical trials has been promoted to prevent publication bias and increase research ...ongoing randomized controlled trials (RCTs) of patient ...

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Towards Understanding of Medical Randomized Controlled Trials by Conclusion Generation

Towards Understanding of Medical Randomized Controlled Trials by Conclusion Generation

... Randomized controlled trials (RCTs) rep- resent the paramount evidence of clinical medicine. Using machines to interpret the massive amount of RCTs has the poten- tial of aiding clinical ...

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OVERVIEW OF RANDOMIZED CONTROLLED TRIALS

OVERVIEW OF RANDOMIZED CONTROLLED TRIALS

... ABSTRACT Randomized controlled trials are considered to be the gold standard in clinical studies to establish level of evidence in medical ...groups. Randomized control trial (RCT) is most ...

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Diagnostic randomized controlled trials: the final frontier

Diagnostic randomized controlled trials: the final frontier

... conducted, randomized controlled trials are the gold standard for assessing the effectiveness and safety of interventions, yet are rarely conducted in the assessment of diagnostic ...diagnostic ...

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Evidence Type Classification in Randomized Controlled Trials

Evidence Type Classification in Randomized Controlled Trials

... e.g., Randomized Controlled Trials or other observational studies, and they usually re- quire transforming the unstructured textual infor- mation into structured information as input of the reasoning ...

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Randomized controlled trials in frontotemporal dementia: cognitive and behavioral outcomes

Randomized controlled trials in frontotemporal dementia: cognitive and behavioral outcomes

... a controlled trial, selection of appropriate measures is crucial, and there are multiple factors to consider in addition to FDA or EMA require- ...in randomized controlled trials in ...

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Randomized Controlled Trials:

Randomized Controlled Trials:

... Finally, conducting RCTs require the collaboration of partner countries and implementing units (NGOs or consultancy firms). This may require collaborative training ef[r] ...

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Bias in randomized controlled trials

Bias in randomized controlled trials

... of trials purporting beneficial effects of a new interven- tion for incurable diseases, while they ignore the results of previ- ous (or concurrent) trials in which the same intervention showed no ...

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How necessary are randomized controlled trials?

How necessary are randomized controlled trials?

... Of course, well designed RCTs try their best to counter these difficulties. And poorly conducted historical studies will also be vulnerable to many of them. The point is only that conducting an RCT is no guarantee – they ...

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Randomized Controlled Trials of Add-On Antidepressants in Schizophrenia

Randomized Controlled Trials of Add-On Antidepressants in Schizophrenia

... Antidepressants seem to have no desirable effect on positive symptoms of schizophrenia, as almost all RCTs were disap- pointing in this respect. The only exception was a study by Joffe and coauthors (2009), in which ...

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Sentence retrieval for abstracts of randomized controlled trials

Sentence retrieval for abstracts of randomized controlled trials

... Address: Centre for Health Informatics, University of New South Wales, Sydney, NSW 2052, Australia Email: Grace Y Chung - [email protected] Abstract Background: The practice of evidence-based medicine (EBM) requires ...

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Registration of randomized controlled trials in nursing journals

Registration of randomized controlled trials in nursing journals

... 1) trials. The majority (83/135, 62%) of trials were not reg- ...of trials were prospectively registered (n = 13/135) and eight percent were prospectively registered with the trial identification ...

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Characteristics of randomized controlled trials of yoga: a bibliometric analysis

Characteristics of randomized controlled trials of yoga: a bibliometric analysis

... the randomized controlled yoga trials published to date, and can serve to inform patients, therapists, and researchers on the available yoga research ...such trials in recent years; based on ...

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