RANTES/CCL5
Aseptic-avascular osteonecrosis: local “silent inflammation” in the jawbone and RANTES/CCL5 overexpression
... Abstract: Of the definitions listed in the International Statistical Classification of Diseases and Related Health Problems, tenth revision (ICD-10), two disease descriptions can be found together: “idiopathic aseptic ...
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Herpes Simplex Virus Selectively Induces Expression of the CC Chemokine RANTES/CCL5 in Macrophages through a Mechanism Dependent on PKR and ICP0
... chemokine RANTES/CCL5 in murine macrophage cell lines and perito- neal ...of RANTES mRNA was detectable after 5 h of infection, was sensitive to UV irradiation of the virus, and was preceded by ...
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Osteoimmunology of tumor necrosis factor-alpha, IL-6, and RANTES/CCL5: a review of known and poorly understood inflammatory patterns in osteonecrosis
... Objective: Are there bone resorptive processes wherein chronic inflammatory conditions are not linked to TNF- α and IL-6 expression, but rather to the expression of other cytokines? Materials and methods: A comprehensive ...
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<p>Ultrasound Sonography to Detect Focal Osteoporotic Jawbone Marrow Defects: Clinical Comparative Study with Corresponding Hounsfield Units and RANTES/CCL5 Expression</p>
... Patients and Methods: TAU-n consists of a two-part handpiece with an extraoral ultra- sound transmitter and an intraoral ultrasound receiver. The TAU-n computer display shows the different jawbone densities with ...
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Role of CCL5 (RANTES) in Viral Lung Disease
... of CCL5 in viral lung disease, we measured its production during primary respiratory syncytial virus (RSV) infection and during secondary infection after sensitizing vaccination that induces Th2-mediated ...of ...
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Frink, Michael (2003): Zur Funktion des CC-Chemokins CCL5/RANTES bei der Immunkomplex-Glomerulonephritis. Dissertation, LMU München: Medizinische Fakultät
... Nach Auswertung aller Ergebnisse haben die verwendeten Chemokinrezeptorantagonisten jedoch das Ziel, eine Verbesserung der Erkrankung herbeizuführen, verfehlt. Obwohl die leukozytäre Infiltration reduziert werden konnte, ...
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Induction of IL 6 and CCL5 (RANTES) in human respiratory epithelial (A549) cells by clinical isolates of respiratory syncytial virus is strain specific
... documented. Several studies suggest that sole investiga- tion of laboratory strains may not be ideal to define and characterize RSV pathogenesis. For example, Line 19, a potential vaccine strain derived from a subgroup A ...
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Effects of chemokines on proliferation and apoptosis of human mesangial cells
... In the kidney expression of chemokines and chemokine receptors are important for the initiation and regulation of inflammatory glomerular diseases [8]. Expression of the chemokines monocyte chemoattractant protein-1 ...
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RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration
... of RANTES/CCL5 thereby limiting tumor macrophage infiltration and inhibition of ...chemokine CCL5 in vitro. We also show that the expression levels of RKIP and CCL5 are inversely correlated ...
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Huppertz, Jérôme (2009): Modulation inflammatorischer Prozesse mittels GPI-verankerter Chemokin-Analoga. Dissertation, LMU München: Medizinische Fakultät
... mutierte RANTES/CCL5 dank seines C-terminalen GPI-Ankers in „leere“ Oberflächenmembranen wieder reintegrieren ...GPI-gekoppelten RANTES-Analoga ein konzentrationsabhängiger Schritt ...
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Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA
... Total RNA was extracted using the RNAeasy kit (Qiagen, Valencia, CA) according to the manufacturer ’ s specifica- tions. Residual genomic DNA was eliminated using on- column DNase digestion with the RNase-free DNase set ...
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Gene Regulation and Functional Alterations Induced by Kaposi's Sarcoma-Associated Herpesvirus-Encoded ORFK13/vFLIP in Endothelial Cells
... mRNAs strongly increased in K13/vFLIP-HUVEC compared to control HUVEC log ratio ⱖ 4 Category and gene abbreviation Chemokines CCL3/MIP1␣ CCL5/RANTES CCL20/MIP3␣ CCL8/MCP2 CXCL2/MIP2␣ CXC[r] ...
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Vα14iNKT Cells Promote Liver Pathology during Adenovirus Infection by Inducing CCL5 Production: Implications for Gene Therapy
... of CCL5-CCR5 blockade on hepatic inflammation and injury during AdLacZ ...with CCL5 antibody (Ab) or Met-RANTES (as described in Materials and Methods) and then infected with AdLacZ for 6 ...
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ASIC1a induces synovial inflammation via the Ca2+/NFATc3/ RANTES pathway
... concentration; CCL5: chemokine C-C motif ligand 5; CFA: Complete Freund’s adjuvant; DAPI: 4′,6-Diamidino-2-phenylindole dihydrochloride; EGTA: ethylene glycol tetraacetic acid; Fluo 3-AM: Fluo 3 acetoxymethyl ...
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Systemic inflammatory response syndrome in a patient diagnosed with high grade inflammatory triple negative breast cancer: a case report of a potentially rare paraneoplastic syndrome
... 1‑alpha; CCL5/RANTES: chemokine (C–C motif ) ligand 5/regulated on activation, normal T cell expressed and secreted; CD14+: cluster of differentia‑ tion 14+; CRP: C‑reactive protein; CT: computer ...
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Met-CCL5 represents an immunotherapy strategy to ameliorate rabies virus infection
... receptors. CCL5 (also termed as RANTES) is a β chemokine and induces leukocyte mi- gration by binding to CCR1, CCR3 or CCR5 ...of CCL5 has been associated with a variety of inflammatory disorders ...
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Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice
... chemokine CCL5 (also known as RANTES), which is induced in murine and human liver after injury, as a central mediator of this ...that CCL5 haplotypes and intrahepatic CCL5 mRNA expression were ...
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Molecular characterization of subcutaneous panniculitis-like T-cell lymphoma reveals upregulation of immunosuppression- and autoimmunity-associated genes
... of CCL5 (known as RANTES), a chemokine mediating the trafficking and homing of T cells [33], in the SPTL samples refers to a Th1 type inflammatory response ...
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Original Article Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation
... chemokine CCL5/RANTES plays an important role in the progression of hepatic in- flammation and ...dose-dependent RANTES induction in ...hepatic RANTES expression in a dietary model of NAFLD, ...
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Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells Role of the angiotensin type 2 receptor
... of RANTES occurs later in this model and may not Figure ...of RANTES mRNA was significantly higher in ANG II–infused animals compared to control-infused ...No RANTES transcripts were de- tectable in ...
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