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Rat Heart

Antioxidant Activity of Ascorbic Acid on Ischemic and Reperfused Rat Heart

Antioxidant Activity of Ascorbic Acid on Ischemic and Reperfused Rat Heart

... Oxidative stress plays a major role in the biochemical and pathological changes associated with myocardial ischemic-reperfusion injury (IRI). The need to identify agents with a potential for preventing such damage has ...

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Hypercholesterolemia downregulates autophagy in the rat heart

Hypercholesterolemia downregulates autophagy in the rat heart

... Insufficient autophagy can promote programmed cell death, apoptosis [26], which results in cardiac damage [27]. Necroptosis (programmed necrosis) is another type of programmed cell death which occurs upon stimula- tion ...

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Effect of parathyroid hormone on rat heart cells

Effect of parathyroid hormone on rat heart cells

... into heart cells and exert deleterious effects on the ...on rat heart cells grown in ...in heart beats, but the effect of 1-84 PTH was significantly greater than that of 1-34 ...effect ...

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EPICARDIAL AUTOFLUORESCENCE NAD(P)H KINETICS IN THE ISCHEMICALLY PRECONDITIONED LANGERDORFF RAT HEART. EFFECTS OF CAPSAICIN. PART 1

EPICARDIAL AUTOFLUORESCENCE NAD(P)H KINETICS IN THE ISCHEMICALLY PRECONDITIONED LANGERDORFF RAT HEART. EFFECTS OF CAPSAICIN. PART 1

... [34] Li Y, Kloner RA. Does protein kinase C play a role in ischemic preconditioning in rat hearts ?. Am J Physiol 1995; 268: H426-H431. [35] Lundmark JL, Ramasamy R, Vulliet PR, Schaefer S. Chelerythrine increases ...

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Preferential oxidation of glycogen in isolated working rat heart

Preferential oxidation of glycogen in isolated working rat heart

... is an estimate of the content of nonradioactive glycogen ex- trapolated back to 20 min of the protocol, at the time when glycogen resynthesis was initiated. We previously found a value of 8263 mmol/gram dry wt for ...

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Effects of interleukin 2 on cardiac function in the isolated rat heart

Effects of interleukin 2 on cardiac function in the isolated rat heart

... Adoptive immunotherapy with IL 2 is associated with severe cardiovascular toxicities including peripheral and pulmonary edema, hypotension decreased systemic vascular resistance, increased heart rate, and an ...

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Micro Computed Tomography Provides Accurate Measurement for Cardiac Function in Infarcted Rat Heart

Micro Computed Tomography Provides Accurate Measurement for Cardiac Function in Infarcted Rat Heart

... the heart is one of the most important information to be evaluated when de- termining the benefit of the ...the heart, as it is nearly to be clinically ...

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Fibronectin expression in the normal and hypertrophic rat heart

Fibronectin expression in the normal and hypertrophic rat heart

... We examined changes in the expression of fibronectin during the induction of cardiac hypertrophy by L-triiodothyronine administration and by mineralocorticoid- and salt-induced experimental hypertension. By use of ...

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Regulation of procollagen metabolism in the pressure overloaded rat heart

Regulation of procollagen metabolism in the pressure overloaded rat heart

... To determine the molecular events responsible for the disproportionate accumulation of myocardial fibrillar collagens during sustained hypertension, we examined the in vivo rate of proco[r] ...

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Cardiac effects of induction agents in the septic rat heart

Cardiac effects of induction agents in the septic rat heart

... isolated heart preparation study is the possible influence of a force-fre- quency ...in heart rate for midazolam, which are not accompanied by a sig- nificant change in +dLVP/dt (Figure 3) at 10 -5 M, the ...

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Evidence of primary cilia in the developing rat heart

Evidence of primary cilia in the developing rat heart

... Results showed primary cilia labelling was not associ- ated with either endothelial cells (RECA-1 labelling, Fig. 4a) or fibroblasts (vimentin labelling, Fig. 4b, h and i) as shown in representative confocal images. ...

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Differential effects of curcumin on vasoactive factors in the diabetic rat heart

Differential effects of curcumin on vasoactive factors in the diabetic rat heart

... in alterations of the cofactors required for several impor- tant antioxidant enzymes. Another mechanisms is an increased flux through the mitochondrial electron trans- port chain; thus, leading to the production of a ...

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THE EFFECT OF FASTING ON THE LIPOPROTEIN LIPASE ACTIVITY OF RAT HEART AND DIAPHRAGM

THE EFFECT OF FASTING ON THE LIPOPROTEIN LIPASE ACTIVITY OF RAT HEART AND DIAPHRAGM

... The greater effect of heparin when heart tissue from fasted animals was used suggests that the increase in lipolytic activity of heart homogenates with fasting is due mainly to an increa[r] ...

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Hypertensive cardiomyopathy  Myocyte nuclei hyperplasia in the mammalian rat heart

Hypertensive cardiomyopathy Myocyte nuclei hyperplasia in the mammalian rat heart

... To determine whether long-term hypertension leads to hyperplasia of myocyte nuclei in the heart, a phenomenon suspected to occur in humans, renal hypertension was produced in rats and the animals were killed 8 mo ...

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Assessing the translatability of In vivo cardiotoxicity mechanisms to In vitro models using causal reasoning

Assessing the translatability of In vivo cardiotoxicity mechanisms to In vitro models using causal reasoning

... One of the proposed advantages in this study is the abil- ity of the causal reasoning approach to abstract similar molecular events from microarray experiments from dif- ferent sources, models and chips, thus overcoming ...

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Moderate exercise training attenuates aging-induced cardiac inflammation, hypertrophy and fibrosis injuries of rat hearts

Moderate exercise training attenuates aging-induced cardiac inflammation, hypertrophy and fibrosis injuries of rat hearts

... of heart failure includes stress-induced cardiac remodeling, cardiac apoptosis, cardiac fibrosis and heart ...the rat heart [11, ...for heart disease ...

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COMPUTER DATABASES FOR TWO DIMENSIONAL ELECTROPHORESIS pdf

COMPUTER DATABASES FOR TWO DIMENSIONAL ELECTROPHORESIS pdf

... University of Siena, Italy 2-DE maps at LSB Corp Human and mouse 2-D PAGE databases: Danish Centre for Human Genome Research RAT HEART-2DPAGE German Heart Institute, Berlin HEART-2DPAGE [r] ...

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Natriuretic peptide receptor mRNAs in the rat and human heart

Natriuretic peptide receptor mRNAs in the rat and human heart

... the heart have yielded conflicting ...in rat and human cardiac tissue. In the rat heart, the distribution of the A and B receptor transcripts appears to be relatively homogeneous; in contrast, ...

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Cardiovascular activity of Labdane Diterpenes from andrographis paniculata in isolated rat hearts

Cardiovascular activity of Labdane Diterpenes from andrographis paniculata in isolated rat hearts

... Many studies have been reported on the cardiovascular activity of A. paniculata [20–28] and on other pharmacolog- ical aspects [3–19]. However, no cardiovascular activity study involving a direct effect on the isolated ...

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EVALUATION OF CARDIOTONIC EFFECT OF HYDROALCOHOLIC LEAF EXTRACT OF NERIUM INDICUM: AN ANIMAL STUDY

EVALUATION OF CARDIOTONIC EFFECT OF HYDROALCOHOLIC LEAF EXTRACT OF NERIUM INDICUM: AN ANIMAL STUDY

... Frog heart & isolated rat, rabbit heart were ...frog heart & isolated rabbit heart while on rat heart no effect was found Conclusion:The result obtained in this ...

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